Antenatal prevention of fetal respiratory distress syndrome and surfactant therapy in premature infants: evaluating the course of prenatal steroids in determining respiratory support tactics

DOI: https://doi.org/10.29296/25877305-2022-02-02
Issue: 
2
Year: 
2022

O. Zavyalov(1, 2); Professor I. Pasechnik(1), MD; Professor I. Ignatko(2, 4), Corresponding
Member of the Academy of Medical Sciences, MD; Zh. Chabaidze(3), Candidate of Medical Sciences; A.
Dementyev(2, 3), Candidate of Medical Sciences; V. Marenkov(2). (1)Central State Medical Academy of the
Administrative Department of the President of Russia, Moscow (2)S.S. Yudin City Clinical Hospital, Moscow
(3)Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia, Moscow
(4)I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

The article is devoted to the issues of practical implementation of antenatal prophylaxis of respiratory distress syndrome (RDS) of the fetus, clinical significance and features of surfactant therapy in the syndrome of respiratory distress of the newborn. Clinical and epidemiological parallels of respiratory pathology in preterm labor are considered. Neonatal features of the respiratory system are discussed and the modern resuscitation concept of the «golden hour» in neonatology is consecrated. The presence, percentage of completeness and completeness of the course of prenatal steroid prophylaxis of fetal RDS was assessed. It has been shown that the screening assessment of this course serves as an important clinical and prognostic predictor in determining the optimal tactics of starting respiratory support in premature infants with extremely low body weight in the neonatal intensive care unit in the early neonatal period.
Keywords: 
respiratory failure
premature infants
perinatology
early neonatal period
resuscitation
respiratory distress of the fetal syndrome
respiratory distress syndrome of the newborn
surfactant therapy
extremely low body weight

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