Multifaceted coronavirus
DOI: https://doi.org/10.29296/25877305-2021-05-01
Issue:
5
Year:
2021
The paper deals with the study and generalization of literature data on the clinical manifestations
of a novel coronavirus infection. SARS-CoV-2 has been identified in most countries, but scientists do not
know much about it. Physicians constantly face the patients who present difficulties in diagnosis and
therapy. The spread of COVID-19 has raised questions for physicians about the definition of the aspects,
diagnosis, and management tactics for patients with this disease. SARS-CoV-2 extends rapidly through the
body, affecting the respiratory system with the development of pneumonia, acute respiratory failure. The
pathogenesis of COVID-19 is mediated by angiotensin converting enzyme-2 receptors. Settling in the body, the
virus affects various human organs and systems. The patients can experience a wide range of symptoms,
including headaches, muscle aches, fatigue, diarrhea, mental confusion, arrhythmias, seizures, loss of
appetite, dyspnea, and many other conditions. However, the disease is asymptomatic or has mild symptoms
(mild malaise and low-grade fever) in many infected people. SARS-CoV-2 begins to destroy the body from the
upper respiratory tract, attacks the lower respiratory tract, subsequently affecting the heart and blood
vessels, gastrointestinal tract, kidneys, skin, central and peripheral nervous systems. Damage to the
internal organs can be so serious that it can lead to death. Currently, information about the epidemiology,
clinical features, prevention and treatment of this disease is formed by specialists from different
countries, but much remains unexplored. Most experts believe that we have seen only the «tip of the
iceberg». This means that the world has faced the poorly understood, dangerous disease that changes its
forms and manifestations.
Keywords:
infectious diseases
coronavirus
lungs
blood vessels
heart
kidneys
nervous system
skin
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