Comorbidity and polypharmacy in the practice of a general practitioner
DOI: https://doi.org/10.29296/25877305-2021-03-06
Issue:
3
Year:
2021
The high prevalence of cardiovascular diseases and their pathophysiological association with
various comorbid conditions contributes to the progressive increase in the number of patients with a
concurrence of several diseases. Combined pathology creates a new clinical situation that requires the
consideration of its features when choosing therapeutic, diagnostic, and preventive strategies. A comorbid
patient is a serious problem for any clinician, since in this case it is necessary to take into account
several components of therapy, which makes it difficult to control treatment efficiency, contributes to an
increase in polypharmacy, the risk of local and systemic side effects of drugs, and reduces adherence to
therapy. Treatment for comorbid disorders requires careful compliance with the requirements of rational
pharmacotherapy, high clinical professionalism, and a wide range of knowledge of related specialties. The
paper describes and discusses the clinical case of a comorbid patient in the practice of a general
practitioner. It gives the steps in the performed diagnostic search, by verifying the clinical diagnosis and
prescribed pharmacotherapy strategies. The presented data show that it is difficult for a physician to avoid
polypharmacy in case of comorbidities. Such difficulties are daily encountered by any clinician regardless
of his/her clinical experience and awareness of medical science.
Keywords:
therapy
comorbidity
polypharmacy
clinical case
diagnosis
treatment
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