Anemic syndrome and its features in patients with disseminated pulmonary tuberculosis and HIV infection
DOI: https://doi.org/10.29296/25877305-2021-02-12
Issue:
2
Year:
2021
Currently, the incidence of HIV infection and pulmonary tuberculosis (PT) comorbidity is
increasing, with disseminated PT making up a major proportion in the pattern of clinical forms of PT. Anemic
syndrome is one of the possible complications of both tuberculosis and HIV infection. Objective: to
investigate the features of anemic syndrome in patients with disseminated PT/HIV infection comorbidity.
Subjects and methods. The investigation enrolled 42 patients with HIV infection and disseminated PT. The
patients’ clinical and social characteristics were studied; the values of a general blood test were
analyzed. Serum iron, ferritin, and hepcidin levels were additionally determined. Statistical data were
processed using the MedCalc 19.2.6 statistical software program. Results. The patients with HIV infection
and disseminated PT were found to have anemia, mainly hypo- or normochromic moderate anemia, in half of the
cases. There was a preponderance of anemia of chronic disease (47.6%), mixed anemia (38.1%), whereas true
iron deficiency anemia was rare (4.8%). Conclusion. The findings may further contribute to the choice of
tactics for the correction of anemic syndrome in patients with HIV infection and disseminated PT.
Keywords:
phthisiology
infectious diseases
disseminated pulmonary tuberculosis
HIV infection
anemia
serum iron
ferritin
hepcidin
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