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An ideal cardiovascular risk biomarker – what is it?

DOI: https://doi.org/10.29296/25877305-2019-09-04
Issue: 
9
Year: 
2019

Yu. Dyleva(1), Candidate of Medical Sciences; O. Gruzdeva(1, 2), MD; E. Uchasova(1), Candidate of Medical Sciences 1-Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo 2-Kemerovo State Medical University

Cardiovascular diseases remain the main cause of high death rates worldwide. Great attention is paid to the early detection and diagnosis of pathological conditions and to the improvement of treatment policy. The advent of high-sensitivity clinical and laboratory studies have made it possible to identify new biological markers for cardiovascular risk, to assess their physiological and pathogenetic role, and to create evidence-based prognostic risk models in addition to the already existing and well-established prognostic scales, which certainly can contribute to the quality of medical care. Today, there are more than 100 new surrogate cardiovascular disease biomarkers, most of which have yet to be studied in detail. The review presents general principles and approaches to assessing biomarkers, key statistical aspects of their study with an emphasis on clinical relevance before any potential biomarker can be put into practice.

Keywords: 
cardiology
biomarker
cardiovascular risk
cardiovascular diseases



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