THE EFFECT OF INFECTIOUS AGENTS ON THE DEVELOPMENT AND COURSE OF CHRONIC IDIOPATHIC URTICARIA

DOI: https://doi.org/10.29296/25877305-2024-07-11
Issue: 
7
Year: 
2024

A. Golovinov(1); Professor V. Gladko(2), MD; Professor E. Sorokina(3, 4), MD;
G. Belyakova(5)
1-Branch No. 8 of N.N. Burdenko Main Military Clinical Hospital, Ministry
of Defense of Russia, Khimki
2-Russian Biotechnical University, Medical Institute of Continuing Education, Moscow
3-I.I. Mechnikov Scientific Research Institute of Vaccines and Serums, Moscow
4-Academy of Postgraduate Education of Federal Scientific and Clinical Center
for Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency, Moscow
5-LLC "Lekar", Krasnogorsk

The article analyzes the infectious load in patients with chronic spontaneous urticaria. The authors analyzed virological and bacteriological laboratory data, assessed the level of infectious load, and identified possible associations with specific types of infections. The results of the study showed that clinical and/or laboratory signs of activity of bacterial agents were observed in 40.66% of patients, signs of activity of viral agents - in 21.43%, combined bacterial-viral pathology - in 23.08%, clinical and laboratory signs of activity of infectious agents were absent in 14.83% of patients. It has been found that certain types of infections, such as herpes simplex virus type 1 and type 2, Epstein-Barr virus, human herpes virus type 6, Helicobacter pylori, can be closely associated with the manifestation of urticaria. The study highlights the importance of studying the infectious load in this nosology in order to develop personalized approaches to the treatment and management of this disease.
Keywords: 
dermatology
chronic idiopathic urticaria
chronic spontaneous urticaria
diagnosis
infection.

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