THE USE OF VITAMIN D PREPARATIONS TAKING INTO ACCOUNT VITAMIN D-DEFICIENT CONDITIONS

DOI: https://doi.org/10.29296/25877305-2024-04-06
Issue: 
4
Year: 
2024

E. Dontsеva(1, 2), Сandidate of Medical Sciences; T. Potupchik(1), Сandidate
of Medical Sciences; I. Gatskikh(1), Сandidate of Medical Sciences; T. Shalda(1)
1-Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry
of Health of Russia
2-Federal Center of Neurosurgery, Ministry of Health of Russia, Novosibirsk

Currently, much attention is being paid to the status of vitamin D as a biomarker of the general state of human health, since low levels of vitamin D are associated with a wide range of diseases. Vitamin D metabolism is complex. Vitamin D and its containers can have genomic and non-genomic activity. The article presents the most common causes of vitamin D deficiency. Screening for vitamin D deficiency is shown in groups of patients with risk factors for its development. Individual features of vitamin D influence caused by genetic polymorphism of the VDR gene are described. For the prevention and treatment of vitamin D-deficient conditions, the use of the vitamin D preparation colecalciferol is recommended. Drugs with high activity calcitriol and alfacalcidol are necessary in certain groups of patients for strict indications, in particular in the complex therapy of osteoporosis.
Keywords: 
vitamin D
metabolism
risk factors
colecalciferol
calcitriol
alfacalcidol.

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