Role of the intestinal microbiota in the development of alopecia areata in celiac disease

DOI: https://doi.org/10.29296/25877305-2023-07-10
Issue: 
7
Year: 
2023

S. Ledentsova(1); Associate Professor P. Seliverstov(2), Candidate of Medical Sciences; E. Ivanyuk(2), Candidate of Medical Sciences; Professor L. Oreshko(2), MD; Professor Yu. Kravchuk(2), MD
1-Consultative and Diagnostic Center of Saint Petersburg State Medical University, Ministry of Health of Russia
2-S.M. Kirov Military Medical Academy, Saint Petersburg

To date, the study of comorbidity from the skin and gastrointestinal tract is a very important task. In recent years, there have been more and more works confirming the role of intestinal microflora in the development of various diseases of the human body, including skin diseases. Thus, the "gut–skin" axis reflects the influence of the intestinal microbiota on the functionality and composition of the innate and adaptive immune system, and vice versa. The mechanisms by which the gut microbiome affects skin health are still not fully understood. To find new ways to treat human skin diseases, it is necessary to deepen our understanding of the relationship between the skin and gut microbiome. Our work is dedicated to this global task.
Keywords: 
dermatology
gastroenterology
skin
microbiota
celiac disease
nest alopecia
gluten.

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