The use of an Internet resource in young people to identify female students at risk for polycystic ovary syndrome

DOI: https://doi.org/10.29296/25877305-2023-04-06
Issue: 
4
Year: 
2023

Professor T. Pestrikova, MD; E. Yurasova, MD; T. Kovaleva, Candidate of Medical Sciences; O. Shcherbakova, Candidate of Medical Sciences; T. Enginoeva;
T. Yurasova
Far Eastern State Medical University, Ministry of Health of Russia, Khabarovsk

Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder caused by both genetic and epigenetic factors. Depending on the period of a woman’s life, the clinical picture, diagnosis, and treatment tactics of the disease are different. The syndrome has a set of reproductive, metabolic, and psychological features. Objective. To study the prevalence of PCOS among female students and to evaluate the effectiveness of using Internet platforms in identifying the manifestations that characterize reproductive health disorders. Subjects and methods. A total of 330 respondents studying in the higher educational establishments of Khabarovsk were interviewed using the Google Forms platform in October to December 2021 in order to identify whether they had irregular menstruation, hyperandrogenism, which was followed by an examination and verification of the diagnosis of PCOS in an outpatient setting. Results. According to the survey results, 87.58% of the respondents did not plan pregnancy in the next 2 years, so infertility as one of the PCOS symptoms did not cause anxiety in them. According to the survey among the female students with an irregular menstrual cycle, the incidence rate of PCOS was 24.7%. Conclusion. In our opinion, the active detection of PCOS in patients with an irregular menstrual cycle among young people using Internet resources allows them to focus their attention on reproductive health disorders and on the need to consult a gynecologist.
Keywords: 
gynecology
polycystic ovary syndrome
irregular menstruation
hyperandrogenism
infertility
reproductive health
young people.

References: 
  1. Синдром поликистозных яичников. Клинические рекомендации. Минздрав России, 2021; 61 с. [Polycystic ovary syndrome. Clinical guidelines. Ministry of Health of the Russian Federation, 2021; 61 p. (in Russ.)].
  2. Teede H.J., Misso M.L., Costello M.F. et al. International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018; 110 (3): 364–79. DOI: 10.1016/j.fertnstert.2018.05.004
  3. Rocha A.L., Oliveira F.R., Azevedo R.C. et al. Recent advances in the understanding and management of polycystic ovary syndrome. F1000Res. 2019; 8: F1000 Faculty Rev-565. DOI: 10.12688/f1000research.15318.1
  4. Долгов В.В., Меньшиков В.В. Клиническая лабораторная диагностика: национальное руководство. Т. I. М.: ГЭОТАР-Медиа, 2012; 928 с. [Dolgov V.V., Menshikov V.V. Clinical laboratory diagnostics: national guidelines. T. I. M.: GEOTAR-Media, 2012; 928 p. (in Russ.)].
  5. Gayoso-Diz P., Otero-González A., Rodriguez-Alvarez M.X. et al. Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocr Disord. 2013; 13: 47. DOI: 10.1186/1472-6823-13-47
  6. Mossmann M., Wainstein M.V., Gonçalves S.C. et al. HOMA-IR is associated with significant angiographic coronary artery disease in non-diabetic, non-obese individuals: a cross-sectional study. Diabetol Metab Syndr. 2015; 7: 100. DOI: 10.1186/s13098-015-0085-5
  7. Международной статистической классификацией болезней и проблем (МКБ-10), связанных со здоровьем (10-й пересмотр). Женева: ВОЗ, 2005 [International Statistical Classification of Diseases and Related Health Problems (10th Revision). Geneva: WHO, 2005 (in Russ.)].
  8. Гинекология. Фармакотерапия без ошибок. Руководство для врачей. Под ред. Г.Т. Сухих, В.Н. Серова, В.Н. Прилепской, И.И. Баранова. М.: Е-ното, 2020; 544 с. [Ginekologiya. Farmakoterapiya bez oshibok. Rukovodstvo dlya vrachei. Pod red. G.T. Sukhikh, V.N. Serova, V.N. Prilepskoi, I.I. Baranova. M.: E-noto, 2020; 544 s. (in Russ.)].
  9. Пестрикова Т.Ю., Юрасова Е.А., Юрасов И.В. и др. Возможности медикаментозной терапии комбинированным оральным контрацептивом, содержащим эстрадиола валерат и диеногест, при обильных маточных кровотечениях (обзор литературы). Проблемы репродукции. 2017; 23 (6): 34–9 [Pestrikova T.Iu., Iurasova E.A., Iurasov I.V. et al. The possibilities of abundant uterine bleeding therapy with combined oral contraceptive containing estradiol valerate and dienogest (a review). Russian Journal of Human Reproduction. 2017; 23 (6): 34–8 (in Russ.)]. DOI: 10.17116/repro201723634-38
  10. Neven A.C.H., Laven J., Teede H.J. et al. A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines. Semin Reprod Med. 2018; 36 (1): 5–12. DOI: 10.1055/s-0038-1668085
  11. Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004; 19 (1): 41–7. DOI: 10.1093/humrep/deh098
  12. Mulder C.L., Lassi Z.S., Grieger J.A. et al. Cardio-metabolic risk factors among young infertile women: a systematic review and meta-analysis. BJOG. 2020; 127 (8): 930–9. DOI: 10.1111/1471-0528.16171
  13. Delitala A.P., Capobianco G., Delitala G. et al. Polycystic ovary syndrome, adipose tissue and metabolic syndrome. Arch Gynecol Obstet. 2017; 296 (3): 405–19. DOI: 10.1007/s00404-017-4429-2
  14. Damone A.L., Joham A.E., Loxton D. et al. Depression, anxiety and perceived stress in women with and without PCOS: a community-based study. Psychol Med. 2019; 49 (9): 1510–20. DOI: 10.1017/S0033291718002076
  15. Brutocao C., Zaiem F., Alsawas M. et al. Psychiatric disorders in women with polycystic ovary syndrome: a systematic review and meta-analysis. Endocrine. 2018; 62 (2): 318–25. DOI: 10.1007/s12020-018-1692-3
  16. Barrionuevo P., Nabhan M., Altayar O. et al. Treatment Options for Hirsutism: A Systematic Review and Network Meta-Analysis. J Clin Endocrinol Metab. 2018; 103 (4): 1258–64. DOI: 10.1210/jc.2017-02052
  17. Пестрикова Т.Ю., Юрасова Е.А., Сухоносова Е.Л. Оценка психоэмоционального состояния у пациенток с синдромом поликистозных яичников на фоне гормональной контрацепции. Гинекология. 2016; 18 (4): 49–54 [Pestrikova T.Iu., Iurasova E.A., Sukhonosova E.L. Evaluation of mental and emotional state of patients with polycystic ovary syndrome on the background of hormonal contraception. Gynecology. 2016; 18 (4): 49–53 (in Russ.)].