A phthisiatrician’s report models during pediatric population screening for tuberculosis

DOI: https://doi.org/10.29296/25877305-2023-01-09
Issue: 
1
Year: 
2023

Associate Professor E. Amosova(1), Candidate of Medical Sciences; Professor B. Borodulin(1), MD; O. Khramkova(1), E. Ilyina1(1), Professor D. Kudlay(2, 3), MD
1-Samara State Medical University, Ministry of Health of Russia
2I-.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
3-NRC Institute of Immunology FMBA of Russia, Moscow

For the early detection of tuberculosis infection, children in Russia undergo screening that is based on annual skin tests with tuberculosis allergens (Mantoux test or Diaskintest). To visit children’s educational establishments, one must have an application for admission, which shows the absence of tuberculosis. Alternative methods are used to diagnose tuberculosis infection when people refuse to undergo skin tests. The paper presents various patient models reflected in the clinical practice guidelines to make a phthisiatrician's report and to issue an application for admission, which contains possible recommendations.
Keywords: 
screening
immunodiagnosis
Mantoux test with 2 TE PPD-L
recombinant tuberculosis allergen
MBT infection
risk factors

References: 
  1. Borodulin B.E., Borodulina E.A., Eremenko E.P. Ambulatornaya ftiziatriya. M., 2022 (in Russ.).
  2. Lozovskaya M.E., Zacharova O., Nickiphorenko N. et al. The effect of tuberculosis infection screening with diaskintest on tuberculosis epidemiological situation in child population of Saint-Petersburg. Vestnik Akademii nauk Moldovy. Meditsina. 2019; 3 (63): 92–6 (in Russ.).
  3. Borodulina E., Amosova E., Borodulin B. et al. Diagnostics with tuberculin in children in modern conditions. Current Pediatrics. 2010; 9 (1): 70–4 (in Russ.).
  4. Usacheva N.E., Myakisheva T.V., Novikov V.E. Immunodiagnostics of tuberculosis infection in children. Vestnik Smolenskoi gosudarstvennoi meditsinskoi akademii. 2021; 20 (1): 101–6 (in Russ.). DOI: 10.37903/vsgma.2021.1.15
  5. Slogotskaya L.V., Bogorodskaya E.M., Senchikhina O.Yu. et al. Formation of risk groups for tuberculosis disease in various immunological methods of the examination of children population. Russian Pediatric Journal. 2017; 20 (4): 207–13 (in Russ.). DOI: 10.18821/1560-9561-2017-20-4-207-213
  6. Borodulina E.A., Akhmerova T.E., Yeremenko E.S. et al. Features of diagnostics of tuberculosis in children using Diaskintest. Epidemiology and Vaccinal Prevention. 2014; 6 (79): 51–5 (in Russ.).
  7. Aksenova V.A., Levi D.T., Aleksandrova N.V. et al. Pediatric TB: Modern Methods for Prevention and Early Diagnostics. Doctor.Ru. 2017; 15 (144): 9–15 (in Russ.).
  8. Aksenova V.A., Klevno N.I., Baryshnikova L.A. et al. Vyyavlenie tuberkuleza i taktika dispansernogo nablyudeniya za litsami iz grupp riska s ispol'zovaniem rekombinantnogo tuberkuleznogo allergena – Diaskintest®. Metodicheskie rekomendatsii. M.: Pervyi MGMU im. I.M. Sechenova, 2011; 12 р. (in Russ.).
  9. Lozovskaja M.E., Nikiforenko N.A., Klochkova L.V. et al. Clinical and epidemiological features of tuberculosis in young children in Saint Petersburg. Pediatrician (St. Petersburg). 2018; 9 (5): 5–12 (in Russ.). DOI: 10.17816/PED955-12
  10. Lozovskaya M.E., Kurova A.S., Vasilieva E.B. et al. Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns. Tuberculosis and Lung Diseases. 2019; 97 (9): 22–7 (in Russ.). DOI: 10.21292/2075-1230-2019-97-9-22-27
  11. Borodulina E., Santalova G., Borodulin B. et al. Tuberculosis infection in children under present conditions. Vrach. 2016; 8: 2–5 (in Russ.).
  12. Borodulina E.V., Borodulina E.A., Gladunova E.P. et al. Medico-social characteristics of newly diagnosed patients with tuberculosis. Medical Alliance. 2018; 3: 41–6 (in Russ.).
  13. Lozovskaya M.E., Klochkova L.V., Vasil'eva E.B. et al. Tuberkulez u detei rannego vozrasta v sovremennykh usloviyakh. Tuberkulez i sotsial'no-znachimye zabolevaniya. 2018; 3: 77–8 (in Russ.).
  14. Santalova G.V., Borodulina E.A., Kudlay D.A. et al. Rheumatic diseases and tuberculosis infection in children and adults. Tuberculosis and Lung Diseases. 2019; 97 (2): 50–5 (in Russ.). DOI: 10.21292/2075-1230-2019-97-2-50-55
  15. Borodulina E.A., Santalova G.V., Kudlay D.A. et al. Monitoring of tuberculosis infection in children with juvenile idiopathic arthritis receiving genetically preparations. Pediatria n.a. G.N. Speransky. 2019; 98 (2): 209–13 (in Russ.). DOI: 10.24110/0031-403X-2019-98-2-209-213
  16. Kozlov V.A., Tikhonova E.P., Savchenko A.A. et al. Klinicheskaya immunologiya. Prakticheskoe posobie dlya infektsionistov. Krasnoyarsk: Polikor, 2021; 563 р. (in Russ.). DOI: 10.17513/np.438
  17. Eremenko E.P., Borodulina E.A., Amosova E.A. HIV infection as a risk factor of tuberculosis in children. Tuberculosis and Lung Diseases. 2017; 95 (1): 18–21 (in Russ.). DOI: 10.21292/2075-1230-2017-95-1-18-21
  18. Borodulina E.A., Borodulin B.E., Amosova E.A. et al. Tuberculin tests and their comparative assessment. Tuberculosis and Lung Diseases. 2010; 87 (8): 13–7 (in Russ.).
  19. Lozovskaya M.E., Zakharova O.P., Yarovaya Yu.A. et al. Two-year experience of test with recombinant tuberculosis allergen for detection of tuberculosis in children in St. Petersburg. Vestnik NovSU. Issue: Medical Sciences. 2020; 3 (119): 43–6 (in Russ.). DOI: 10.34680/2076-8052.2020.3(119).43-46
  20. Lozovskaya M.E., Belushkov V.V., Gurina O.P. et al. Comparative evaluation of innovative diagnostic tests for latent and active TВ infection in children. Pediatrician (St. Petersburg). 2014; 5 (3): 46–50 (in Russ.). DOI: 10.17816/PED5346-50
  21. Eremenko E.P., Borodulina E.A., Sergeeva I.A. et al. Recombinant in vitro test T-SPOT.TB as a screening method for early diagnosis of tuberculosis infection. Tuberculosis and Lung Diseases. 2020; 98 (4): 48–52 (in Russ.). DOI: 10.21292/2075-1230-2020-98-4-48-52
  22. Borodulina E., Kudlay D., Vlasova B. et al. Potential use of in vitro tests in the diagnosis of tuberculosis (literature review). Medical Alliance. 2021; 9 (2): 15–21. DOI: 10.36422/23076348-2021-9-2-15-21
  23. Shovkun L.A., Aksenova V.A., Kudlai D.A. et al. The role of immunological tests in the diagnosis of tuberculosis infection in children with juvenile idiopathic arthritis (JIA). Eur Resp J. Suppl. 2018; 52 (S62): PA2733.
  24. Lozovskaya M.E., Gurina O.P., Dementyeva E.A. et al. Features of reaction in vitro tests and skin tests with tubercular allergens depending on variants of the tuberculosis infection in children. Meditsina: teoriya i praktika. 2018; 3 (S): 13–8 (in Russ.). DOI: 10.18821/0869-2084-2016-61-12-838-842
  25. Borodulin B.E., Borodulina E.A., Ftiziatriya.Uchebnoe posobie. M.: OOO «Izdatelstvo KNORUS», 2021; 212 р. (in Russ.).
  26. Gyulumyan V.G. Proportionality of Mass Tuberculin Diagnostics and Public Health Purposes. Meditsinskoe pravo. 2017; 1: 16–20 (in Russ.).
  27. Gyulumyan V.G. Responsibility of Children Failed to Pass Tuberculous Examination. Issues of Juvenile Justice. 2016; 4: 12–4 (in Russ.).
  28. Aksenova V.A., Klevno N.I., Baryshnikova L.A. Vyyavlenie i diagnostika tuberkuleza u detei, postupayushchikh i obuchayushchikhsya v obshcheobrazovatel'nykh organizatsiyakh: Klinicheskie rekomendatsii. M., 2017; 40 р. (in Russ.).