Novel coronavirus infection (COVID-19): epidemiology, clinical characteristics of patients, risk of complications, prevention, use of selenium-containing drugs

DOI: https://doi.org/10.29296/25877305-2022-05-12
Issue: 
5
Year: 
2022

Professor D. Dedov, MD
Tver State Medical University
Tver Regional Clinical Cardiology Dispensary

The article presents an analysis of Russian and foreign publications. The authors reflected the epidemiology, clinical characteristics of patients and risk of complications in patients with novel coronavirus infection (COVID-19). They noted correlations of selenium (Se) deficiency and severity of the course of the said disease. Se deficiency was associated with oxidative stress, hyperinflammation, complications of COVID-19. Showed the need for sufficient serum Se for proper functioning of the immune, reproductive systems, thyroid gland, brain. Recognized that the organic form of Se (selenocystin) had high bioavailability. Concluded that the severity of the course of COVID-19, along with other risk factors, may be related to the low serum Se content of patients. Additional prescription of selenium-containing drugs requires an individual approach, considering the data of complex clinical and instrumental examination, comorbid diseases existing in patients. Administration of SELENBIO for women may be recommended for complex prophylaxis of COVID-19, increasing of body adaptation potential and maintenance of healthy immune system.
Keywords: 
novel coronavirus infection
epidemiology
clinical characteristics
patients
complications
selenium-containing drugs
SELENBIO for women
selenocysteine
Astragalus dasyanthus Pall

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