Hypertrophic cardiomyopathy and pregnancy
DOI: https://doi.org/10.29296/25877305-2021-08-04
Issue:
8
Year:
2021
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease. Owing to achievements
in medicine over recent decades, the number of pregnancies in women with HCM is increasing and will continue
to grow in the future. In most women with HCM, pregnancy proceeds without complications; however, during
gestation, the risk of adverse cardiovascular events is increased, especially in symptomatic patients who
had a high left ventricular outflow tract gradient, heart failure (HF), or arrhythmias before conception. A
high functional class of HF prior to pregnancy is statistically significantly associated with an increased
risk of cardiovascular complications during pregnancy or in the postpartum period. In this connection, a
detailed cardiovascular system assessment in a patient with HCM is needed to determine the potential risks
associated with pregnancy and childbirth and to develop an appropriate therapeutic strategy. The review
presents the latest national and international guidelines for the diagnosis and management of pregnant women
with HCM. It is emphasized that the clinical manifestations and diagnosis of HCM during pregnancy have a
number of features and when prescribing medications, it is necessary to take into account their possible
negative impact on the health of the mother and fetus.
Keywords:
cardiology
obstetrics and gynecology
hypertrophic cardiomyopathy
pregnancy
left ventricular hypertrophy
cardiovascular diseases
heart failure
arrhythmias
atrial fibrillation
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