Occupational asthma (workplace asthma): diagnosis, examination of the association between disease and occupation, as well as treatment

DOI: https://doi.org/10.29296/25877305-2021-07-03
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Issue: 
7
Year: 
2021

Professor S. Babanov(1), MD; Professor L. Strizhakov(2), MD; A. Baikova(1); M.
Vostroknutova(1); A. Agarkova(1); N. Ostryakova(1); T. Kiryushina(1) (1)Samara State Medical University,
Ministry of Health of Russia (2)I.M. Sechenov First Moscow State Medical University (Sechenov University),
Ministry of Health of Russia

The paper is devoted to one of the most common occupational diseases, such as occupational asthma (OA) that occurs under industrial and agricultural production conditions when exposed to high- and low-molecular-weight compounds. It presents the main chemical and biological factors that are etiological factors of OA, as well as the main professions that are susceptible to this disease. The paper formulates the basic principles of the diagnosis of OA, the principles of its treatment, prevention, and examination of the association between disease and occupation, and professional suitability.

Keywords: 
pulmonology
occupational asthma
high- and low-molecular-weight compounds
treatment
prevention
examination of the association between disease and occupation



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References: 
  1. Professional'nye zabolevanija organov dyhanija. Natsional'noe rukovodstvo. Pod red. N.F. Izmerova, A.G. Chuchalina. M.: GEOTAR-Media, 2015; 792 s. [Occupational respiratory diseases. National guidelines. Ed. N.F. Izmerov, A.G. Chuchalin. M.: GEOTAR-Media, 2015; 792 r. (in Russ.)].
  2. Kosarev V.V., Babanov S.A. Professional'nye bolezni. M.: GEOTAR-Media; 2010; 368 s. [Kosarev V.V., Babanov S.A. Occupational diseases. M.: GEOTAR-Media; 2010; 368 r. (in Russ.)].
  3. Professional'naja patologija. Natsional'noe rukovodstvo. Pod red. N.F. Izmerova. M.: GEOTAR-Media, 2011; 784 s. [Occupational pathology. National manual. Ed. N.F. Izmerov. M.: GEOTAR-MEDIA, 2011; 784 p. (in Russ.)].
  4. Saakadze V.P., Stepanov S.A. Professional'naja bronhial'naja astma. Saratov, 1989; s. 17–41 [Saakadze V.P., Stepanov S.A. Occupational asthma. Saratov, 1989; s. 17–41 (in Russ.)].
  5. GINA Report, Global Strategy for Asthma Management and Prevention. URL: http://www.ginasthma.org
  6. Stepanov S.A. K voprosu o prirode tak nazyvaemoj «zernovoj lihoradki». Kazanskij meditsinskij zhurnal. 1968; 8: 8–13 [Stepanov S.A. About the nature of the «grain fever». Kazan Medical Journal. 1968; 8: 8–13 (in Russ.)].
  7. Maestrelli P., Saetta M., Mapp C. et al. Mechanisms of occupational asthma. Clin Exp Allergy. 1997; 27 (suppl. 1): 47–54. DOI: 10.1111/j.1365-2222.1997.tb01826.x
  8. Maestrelli P., del Prete G.F., de Carli M. et al. CD8 Tcell clones producing interleukin5 and interferongamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. Scand J Work Environ Hlth. 1994; 20: 376–81. DOI: 10.5271/sjweh.1383
  9. Makova E.V. Klinicheskie i immunologicheskie aspekty professional'noj allergii k natural'nomu lateksu. Avtoref. diss. ... kand. med. nauk. Samara, 2003; 24 s. [Makova E.V. Klinicheskie i immunologicheskie aspekty professional’noi allergii k natural’nomu lateksu. Avtoref. diss. ... kand. med. nauk. Samara, 2003; 24 s. (in Russ.)].
  10. Klinicheskie rekomendatsii. Bronhial'naja astma. Pod red. A.G. Chuchalina. M.: Izd-vo Atmosfera, 2008; 224 [Clinical guidelines. Bronchial asthma. Ed. A.G. Chuchalin. M .: Atmosfera, 2008; 224 (in Russ.)].
  11. Kosarev V.V., Babanov S.A. Professional'nye zabolevanija meditsinskih rabotnikov. Samara: Ofort, 2009; 232 s. [Kosarev V.V., Babanov S.A. Occupational diseases of medical workers. Samara: Ofort, 2009; 232 r. (in Russ.)].
  12. Kosarev V.V., Babanov S.A. Spravochnik vracha-pul'monologa. Rostov-na-Donu: Feniks, 2011; 446 s. [Kosarev V.V., Babanov S.A. Spravochnik vracha-pul’monologa. Rostov-na-Donu: Feniks, 2011; 446 r. (in Russ.)].
  13. Tilles S.A., Jerath1-Tatum A. Differential diagnosis of occupational asthma. Immunol Allergy Clin N Am. 2003; 23: 167–76. DOI: 10.1016/s0889-8561(02)00089-9
  14. Sastre J., Vandesplas O., Park H.S. Pathogenesis of occupational asthma. Eur Respir J. 2003; 22: 364–67. DOI: 10.1183/09031936.03.00045103
  15. Wan H., Winton H.L., Soeller C. et al. Der p1 facilitates transepithelial allergen delivery by disruption of tight functions. J Clin Invest. 1999; 104: 123–33. DOI: 10.1172/JCI5844
  16. Agius R.M., Nee J., Mc Govern B. et al. Structure activity hypotheses in occupational asthma caused by low molecular weight substances. Ann Occup Hyg. 1991; 35: 129–37. DOI: 10.1093/annhyg/35.2.129
  17. Kozlov V.A., Savchenko A.A., Kudrjavtsev I.V. i dr. Klinicheskaja immunologija. Krasnojarsk: Polikor, 2020; 386 s. [Kozlov V.A., Savchenko A.A., Kudryavtsev I.V. et al. Klinicheskaya immunologiya. Krasnoyarsk: Polikor, 2020; 386 s. (in Russ.)]. DOI: 10.17513/np.438
  18. Saetta M., Di Stefano A., Maestrelli P. et al. Airway mucos al inflammation in occupational asthma induced by toluene diisocyanate. Am Rev Respir Dis. 1992; 145: 160–8. DOI: 10.1164/ajrccm/145.1.160
  19. Frew A.J., Chan H., Lam S. et al. Bronchial inflammation in asthma due to western red cedar. Am J Respir Crit Care Med. 1995; 151: 340–4. DOI: 10.1164/ajrccm.151.2.7842189
  20. Petrovskaja E.V. Kliniko-immunologicheskie osobennosti professional'noj bronhial'noj astmy. Avtoref. diss. … kand. med. nauk. Samara, 2009; 24 s. [Petrovskaya E.V. Kliniko-immunologicheskie osobennosti professional’noi bronkhial’noi astmy. Avtoref. diss. … kand. med. nauk. Samara, 2009; 24 r. (in Russ.)]
  21. Rabe K.F., Atienza T., Magyar P. et al. Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study. Lancet. 2006; 368 (9537): 744–53. DOI: 10.1016/S0140-6736(06)69284-2
  22. Vogelmeier C., D’Urzo A., Pauwels R. et al. Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? Eur Respir J. 2005; 26 (5): 819–28. DOI: 10.1183/09031936.05.00028305
  23. Muhin N.A., Kosarev V.V., Babanov S.A. i dr. Professional'nye bolezni. M.: GEOTAR-Media, 2016; 512 s. [Mukhin N.A., Kosarev V.V., Babanov S.A. et al. Occupational diseases. M.: GEOTAR-Media, 2016; 512 r. (in Russ.)].
  24. Kosarev V.V., Babanov S.A. Professional'nye zabolevanija organov dyhanija. M.: Infra-M, 2013; 110 s. [Kosarev V.V., Babanov S.A. Occupational respiratory diseases. M.: Infra-M, 2013; 110 s. (in Russ.)].
  25. Agafonova O.V., Gritsenko T.A., Bogdanova Ju.V. i dr. Poliklinicheskaja terapija: Uchebnik. Pod red. D.I. Davydkina, Ju.V. Schukina. 2-e izd., pererab. i dop. M.: GEOTAR-Media, 2020; 840 s. [Agafonova O.V., Gritsenko T.A., Bogdanova Yu.V. et al. Poliklinicheskaya terapiya: Uchebnik. Pod red. D.I. Davydkina, Yu.V. Shchukina. 2-e izd., pererab. i dop. M.: GEOTAR-Media, 2020; 840 s. (in Russ.)]. DOI: 10.33029/9704-5545-6-PLT-2020-1-840