Possibilities of using the disinfectant Anolyte ANC Super in healthcare facilities

DOI: https://doi.org/10.29296/25877305-2021-05-13
Download full text PDF
Issue: 
5
Year: 
2021

L. Ipatova(1), Doctor of Engineering Sciences; S. Marchenko(2, 3), Candidate of Pharmaceutical
Sciences; T. Potupchik(4), Candidate of Medical Sciences 1«Delfin Aqua», Moscow (2)I.M. Sechenov First
Moscow State Medical University (Sechenov University), Ministry of Health of Russia (3)N.I. Pirogov Russian
National Research University, Moscow (4)Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University,
Ministry of Health of Russia

The paper provides information about the use of electrochemically activated anolyte for disinfection in healthcare facilities. It presents the data of studies that have shown that the agent has a high antimicrobial activity against a broad spectrum of pathogenic microorganisms. The complex of equipment produced by the «Delfin Aqua» for the preparation of the agent Anolyte ANC Super can be recommended for use in the healthcare facilities, which will be able to produce a ready-to-use disinfectant in the required amounts. This agent has a minimum toxicity class and is environmentally friendly, as the product of its natural degradation is fresh water.
Keywords: 
disinfection
healthcare facilities
electrochemical synthesis
Anolyte ANC Super

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Archakov A.I., Karuzina I.I.  Okislenie chuzherodnyh soedinenij i problemy toksikologii. Vestnik AMN SSSR. 1988; 1: 14–28 [Archakov A.I., Karuzina I.I. Oxidization of foreign compounds and problems of toxicology. Vestnik AMN SSSR. 1988; 1: 14–28 (in Russ.)].
  2. Bahir  V.M., Zadorozhnij  Ju.G., Barabash T.B. Ustrojstvo dlja elektrohimicheskoj obrabotki vody. Svidetel'stvo RF na poleznuju model' № 3601. Zajavleno 27.11.1995, opublikovano 16.02.1997 [Bahir V.M., Zadorozhny Yu.G., Barabash T.B. Device for electrochemical water treatment. Certificate of the Russian Federation for utility model No. 3601. Posted on 27.11.1995, published on 16.02.1997 (in Russ.)].
  3. Bahir V. M. Elektrohimicheskaja aktivatsija. Izobretenija, tehnika, tehnologija. M.: Viva-Press, 2014; 500 s. [Bakhir V. M. Elektrokhimicheskaya aktivatsiya. Izobreteniya, tekhnika, tekhnologiya. M.: Viva-Press, 2014; 500 s. (in Russ.)].
  4. Bahir V.M. Effektivnost' i bezopasnost' himicheskih sredstv dlja dezinfektsii predsterilizatsionnoj ochistki i sterilizatsii. Dezinfektsionnoe delo. 2003; 1: 29–36 [Bahir V.M. Efficiency and safety of chemical agents for disinfection of pre-sterilization cleaning and sterilization. Dezinfektsionnoe delo. 2003; 1: 29–36 (in Russ.)].
  5. Vladimirov Ju.A. Svobodnye radikaly v biologicheskih sistemah. Sorosovskij Obrazovatel'nyj Zhurnal. 2000; 6 (12): 13–9 [Vladimirov Yu.A. Svobodnye radikaly v biologicheskikh sistemakh. Sorosovskii Obrazovatel’nyi Zhurnal. 2000; 6 (12): 13–9 (in Russ.)].
  6. Global'nye prakticheskie rekomendatsii Vsemirnoj Gastroenterologicheskoj Organizatsii. Dezinfektsija endoskopa (obnovlenie): Rukovodstvo po resurso-chuvstvitel'noj obrabotke. World Gastroenterology Organisation. Aprel' 2019; 28 s. [Elektronnyj resurs] [Global’nye prakticheskie rekomendatsii Vsemirnoi Gastroenterologicheskoi Organizatsii. Dezinfektsiya endoskopa (obnovlenie): Rukovodstvo po resurso-chuvstvitel’noi obrabotke. World Gastroenterology Organisation. Aprel’ 2019; 28 s. [Elektronnyi resurs] (in Russ.)] URL: https://www.worldgastroenterology.org/UserFiles/file/guidelines/endoscope-disinfection-russian-2019.pdf
  7. Golohvast K.S., Ryzhakov D.S., Chajka V.V. Perspektivy ispol'zovanija elektrohimicheskoj aktivatsii rastvorov. Voda: himija i ekologija. 2011; 2: 23–8 [Golokhvast K.S., Ryzhakov D.S., Chaika V.V. Prospects for the use of electrochemical activation of solutions. Water: chemistry and ecology. 2011; 2: 23–30 (in Russ.)].
  8. Dontsov V.I., Krut'ko V.N., Mrikaev B.M. i dr. Aktivnye formy kisloroda kak sistema: znachenie v fiziologii, patologii i estestvennom starenii. Trudy ISA RAN. 2006; 19: 50–69 [Dontsov V.I., Krut’ko V.N., Mrikaev B.M. et al. Aktivnye formy kisloroda kak sistema: znachenie v fiziologii, patologii i estestvennom starenii. Trudy ISA RAN. 2006; 19: 50–69 (in Russ.)].
  9. Instruktsija № DA 005-13 po primeneniju dezinfitsirujuschego sredstva Anolit ANK SUPER firmy OOO «Delfin Akva» dlja tselej dezinfektsii i sterilizatsii. Moskva. Soglasovano FBUZ «TsNII epidemiologii Rospotrebnadzora». 2013; 19 s. [Instruktsiya № DA 005-13 po primeneniyu dezinfitsiruyushchego sredstva Anolit ANK SUPER firmy OOO «Delfin Akva» dlya tselei dezinfektsii i sterilizatsii. Moskva. Soglasovano FBUZ «TsNII epidemiologii Rospotrebnadzora». 2013; 19 s. (in Russ.)]
  10. Instruktsija № DA 006-14 po primeneniju dezinfitsirujuschego sredstva Anolit ANK SUPER firmy OOO «Delfin Akva» dlja predsterilizatsionnoj ochistki izdelij meditsinskogo naznachenija. Moskva. Soglasovano GUP «Moskovskij gorodskoj tsentr dezinfektsii». 2014; 12 s. [Instruktsiya № DA 006-14 po primeneniyu dezinfitsiruyushchego sredstva Anolit ANK SUPER firmy OOO «Delfin Akva» dlya predsterilizatsionnoi ochistki izdelii meditsinskogo naznacheniya. Moskva. Soglasovano GUP «Moskovskii gorodskoi tsentr dezinfektsii». 2014; 12 s. (in Russ.)]
  11. Mamatkulov I.H., Madaminov M.S. Antimikrobnaja aktivnost' nejtral'nogo anolita v sravnenii s drugimi dezinfektantami i razrabotka ekspress-metoda ee testirovanija. Bakteriologija. 2016; 1 (1): 37–41 [Mamatkulov I.Kh., Madaminov M.S. Antimicrobial activity of neutral anolyte vs some other disinfectans; developing an express-assay to assess it. Bacteriology. 2016; 1 (1): 37–41 (in Russ.)]. DOI: 10.20953/2500-1027-2016-1-37-41
  12. Miklis N.I., Burak I.I., Charnovska I.V. Primenenie elektrohimicheski aktivirovannyh rastvorov v uchrezhdenijah obrazovanija. Vestnik Vitebskogo gosudarstvennogo meditsinskogo universiteta. 2009; 8 (2): 97–105 [Miklis N.I., Burak I.I., Charnovska I.V. Primenenie elektrokhimicheski aktivirovannykh rastvorov v uchrezhdeniyakh obrazovaniya. Vestnik Vitebskogo gosudarstvennogo meditsinskogo universiteta. 2009; 8 (2): 97–105 (in Russ.)].
  13. Panasenko O.M., Gorudko I.V., Sokolov A.V. Hlornovatistaja kislota kak predshestvennik svobodnyh radikalov v zhivyh sistemah. Uspehi biologicheskoj himii. 2013; 53: 195–244 [Panasenko O.M., Gorudko I.V., Sokolov A.V. Khlornovatistaya kislota kak predshestvennik svobodnykh radikalov v zhivykh sistemakh. Uspekhi biologicheskoi khimii. 2013; 53: 195–244 (in Russ.)].
  14. Plutahin G.A., Koschaev A.G., Aider M. Praktika ispol'zovanija elektroaktivirovannyh vodnyh rastvorov v agropromyshlennom komplekse. Politematicheskij setevoj elektronnyj nauchnyj zhurnal Kubanskogo gosudarstvennogo agrarnogo universiteta. 2013; 9 (093): 497–511 [Plutakhin G.A., Koshchaev A.G., Aider M. The practice of using electro-activated water solutions in agroindustrial complex. Politematicheskii setevoi elektronnyi nauchnyi zhurnal Kubanskogo gosudarstvennogo agrarnogo universiteta. 2013; 9 (093): 497–511 (in Russ.)]. URL: http://ej.kubagro.ru/2013/09/pdf/33.pdf
  15. Prilutskij V. I., Dolgopolov V.I., Barabash T. B. Anolity na rynke dezsredstv: ne oshibites' v vybore! Meditsinskij alfavit. Epidemiologija i gigiena. 2013; 3: 52–61 [Prilutsky V.I., Dolgopolov V.I., Barabash T.B. Anolites on the market of dezsredstv: do not make a mistake in the choice! Medical alphabet. Epidemiology and hygiene. 2013; 3: 52–61 (in Russ.)].
  16. Chesnokova N.P., Ponukalina E.V., Bizenkova M.N. Istochniki obrazovanija svobodnyh radikalov i ih znachenie v biologicheskih sistemah v uslovijah normy. Sovremennye naukoemkie tehnologii. 2006; 6: 28–34 [Chesnokova N.P., Ponukalina E.V., Bizenkova M.N. The sources of free radicals formation and their significance in biological systems in normal environment. Modern high technologies. 2006; 6: 28–34 (in Russ.)].
  17. Beilenhoff U., Neumann C.S., Rey J.F. et. al. ESGE+ESGENA guideline: Cleaning and disinfection in gastrointestinal endoscopy Update 2008. Endoscopy. 2008; 40 (11): 939–57. DOI: 10.1055/s-2008-1077722
  18. Block M.S., Rowan B.G. Hypochlorous Acid: A Review, American Association of Oral and Maxillofacial Surgeons. J Oral Maxillofac Surg. 2020; 78: 1461–6. DOI: 10.4236/jwarp.2019.113014. URL: https://www.joms.org/article/S0278-2391(20)30672-8/fulltext
  19. Boyce J.M. Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals. Antimicrobial Resistance and Infection Control. 2016; 5: 10. DOI: 10.1186/s13756-016-0111-x
  20. Deza M.A., Araujo M., Garrido M. Efficacy of Neutral Electrolyzed Water To Inactivate Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, and Staphylococcus aureus on Plastic and Wooden Kitchen Cutting Boards. J Food Prot. 2007; 70 (1): 102–8. DOI: 10.4315/0362-028x-70.1.102
  21. Fertelli D., Jennifer L. Cadnum J.C. et al. Effectiveness of an Electrochemically Activated Saline Solution for Disinfection of Hospital Equipment. Infect Control Hosp Epidemiol. 2013; 34 (5): 543–4. DOI: 10.1086/670226
  22. Hricova D., Stephan R., Zweifel C. Source Electrolyzed Water and Its Application in the Food Industry. J Food Prot. 2008; 71 (9): 1934–47. DOI: 10.4315/0362-028x-71.9.1934
  23. Ignatov I., Gluhchev G.G., Karadzhov S. et al. Preparation of Electrochemically Activated Water Solutions (Catholyte / Anolyte) and Studying Their Physical-Chemical Properties. J Med Physiol Biophys. 2015; 13 URL: https://iiste.org/Journals/index.php/JHMN/article/view/22411
  24. Moorman E., Montazeri N., Jaykus L.-A. Efficacy of neutral electrolyzed water for inactivation of human norovirus. Appl Environ Microbiol. 2017; 83: e00653-17. DOI: 10.1128/AEM.00653-17
  25. Ogunniyi A.D., Dandie C.E., Ferro S. et al. Comparative antibacterial activities of neutral electrolyzed oxidizing water and other chlorine-based sanitizers. Sci Rep. 2019; 9: 19955. DOI: 10.1038/s41598-019-56248-7
  26. Pintaric R. et al. Suitability of electrolyzed oxidizing water for the disinfection of hard surfaces and equipment in radiology. J Environ Health Sci Eng. 2015; 13: 6. DOI 10.1186/s40201-015-0160-8
  27. Rahman S.M., Ding T., Oh D.H. Effectivenes of low concentration electrolyzed water to inartivate foodbozne pathogenes under different environmental conditions. Int J Food Microbiol. 2010; 139 (3): 147–53. DOI: 10.1016/j.ijfoodmicro.2010.03.020
  28. Rogers J.V., Ducatte G.R., Choi Y.W. et al. A preliminary assessment of Bacillus anthracis spore inactivation using an electrochemically activated solution (ECASOLTM). Lett Appl Microbiol. 2006; 43 (5): 482–8. DOI: 10.1111/j.1472-765X.2006.02002.x Samara F., Badran R., Dalibalta S. Are Disinfectants for the Prevention and Control of COVID-19 Safe? Health Security. 2020; 18 (6). DOI: 10.1089/hs.2020.0104. URL: https://www.liebertpub.com/doi/full/10.1089/hs.2020.0104
  29. Stopforth J.D., Mai T., Kottapalli B. et al.  Effect of Acidified Sodium Chlorite, Chlorine, and Acidic Electrolyzed Water on Escherichia coli O157: H7, Salmonella, and Listeria monocytogenes Inoculated onto Leafy Greens. J Food Prot. 2008; 71 (3): 625–8. DOI: 10.4315/0362-028x-71.3.625
  30. Thorn R.M.S., Lee S.W.H., Robinson G.M. et al. Electrochemically activated solutions: evidence for antimicrobial efficacy and applications in healthcare environments. Eur J Clin Microbiol Infect Dis. 2012; 31 (5): 641–53. DOI 10.1007/s10096-011-1369-9.
  31. U.S. Environmental Protection Agency List N Advanced Search Page: Disinfectants for Coronavirus (COVID-19). URL: https://www.epa.gov/coronavirus/list-n-advanced-search-page-disinfectants-coronavirus-covid-19
  32. U.S. Food & Drug Administration. Environmental Assessment for Food Contact Notification FCN 1811; U.S. Food & Drug Administration: Silver Spring, MD, USA, 2017. URL: https://www.fda.gov/food/environmental-decisions/environmental-decision-memo-food-contact-notification-no-1811
  33. Winter J., Ilbert M., Graf P.C.F. et al. Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding. Cell. 2008; 135: 691–701. DOI: 10.1016/j.cell.2008.09.024
  34. Yan P., Daliri E.B., Oh D.-H. New Clinical Applications of Electrolyzed Water: A Review. Microorganisms. 2021; 9: 136. DOI: 10.3390/microorganisms9010136