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Peptide bioregulators applying perspectives for skin structure restoration in middle aged women

DOI: https://doi.org/10.29296/25877305-2020-09-11
Issue: 
9
Year: 
2020

N. Fridman(1, 2), L. Bojko(2), Professor S. Trofimova(1), MD (1)Saint Petersburg Institute of
Bioregulation and Gerontology (2)ArtMediJa LTD, Saint Petersburg

The decreasing of skin cells regeneration in middle-aged women do the priority the investigation minimally invasive procedures for restoration of this process. The perspective substances for skin aging slowing is peptides. The goal of the work is to investigate peptide bioregulators influence on the structure of face skin of middle-aged women. Material and methods. The investigation of face skin was realized on 30 women of 44–59 years old by ultrasound diagnostic. Patients of the control group had electrophoresis with physiological solution. Women in the 1st base group had electrophoresis with KED, EDR, EDP and EDG peptides. Patients in the 2nd base group had the same as in the 1st group and per os applying polypeptide complexes of pineal gland, cartilage and ovary. Subjective effect was analyzed by enquirer. Results. Short peptides and short peptides with polypeptides complexes increased the subjective quantity of patient’s life. The applying of short peptides with polypeptides complexes increased thickness index of epidermis on 50% and derma – on 33%. Short peptides with polypeptides complexes increased hypoechogenic of derma by the data of ultrasound investigation. It shown the peptides ability to stimulate collagen synthesis by skin fibroblasts. Conclusion. Combined applying of KED, EDR, EDP, EDG short peptides by electrophoresis with per os applying of polypeptides complexes of pineal gland, cartilage and ovary decreased skin aging in middle-aged women.

Keywords: 
dermatology
short peptides
polypeptide complexes
ultrasound investigation
electrophoresis
skin
aging



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