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Plant sorbents in combination anthelmintic therapy

DOI: https://doi.org/10.29296/25877305-2020-06-08
Issue: 
6
Year: 
2020

E. Chernysheva(1), Candidate of Medical Sciences; E. Babaeva(2), Candidate of Biological Sciences; A. Yuryeva(3); S. Nikolaeva(4); D. Vychuzhanin(5), Candidate of Medical Sciences (1)Ivanteevka Central Town Hospital, Ivanteevka, Moscow Region (2)All-Russian Research Institute of Medicinal and Aromatic Plants, Moscow (3)RZhD-Meditsina Central Clinical Hospital, Moscow (4)Akademiya Zdoroviya (Academy of Health) Medical Center, Yaroslavl (5)I.M. Sechenov First Moscow State Medical University (Sechenov University)

The task has been completed by choosing and using sorbents in the dehelmintization pro-cess. Objective: to determine the efficiency of detoxification in patients diagnosed with helmin-thiases. To study the combined use of anthelmintic agents and plant sorbents for endotoxemia elimination and in the dehelmintization process. Subjects and methods. There were a total of 180 patients, including 41% with skin allergy and 59% with gastrointestinal tract diseases. The patients took nemozole tablets for dehelmintiza-tion. They used in parallel plant enterosorbents, such as bran, zosterin-ultra, beet root powder. En-terosgel was used as a control. Fecal changes were monitored by histological and coprological sur-veys. Results and discussion. Pectins have a fairly potent sorption activity and, unlike the con-trol (enterosgel), antibacterial, therapeutic, and nutritional effects. The use of enterosorbents is mandatory in all patients before and during dehelmintization. Patients with a family history of al-lergy should additionally take antihistamines.

Keywords: 
gastroenterology
plant sorbents
dehelmintization
allergic reactions
gastrointestinal tract diseases



References: 
  1. Nikolaev V.G., Mihalovskij S.V., Gurina N.M. Sovremennye enterosorbenty i mehanizmy ih dejstvija. Obzor. Efferentnaja terapija. 2005; 11 (4): 3–17 [Nikolayev V.G., Mikhalovsky S.V., Gurina N.M. Modern enterosorbents and mechanisms of their action. Efferentnaya terapiya. 2005; 11 (4): 3–17 (in Russ.)].
  2. Kosova I.V., Terehova L.V. Sovremennaja enterosorbtsija – fundament ratsional'noj farmakoterapii. Uchebno-metodicheskoe posobie po klinicheskoj farmakologii. M.: RUDN, 2014; 40 s. [Kosova I.V., Terekhova L.V. Sovremennaya enterosorbtsiya – fundament ratsional’noi farmakoterapii. Uchebno-metodicheskoe posobie po klinicheskoi farmakologii. M.: RUDN, 2014; 40 s. (in Russ.)].
  3. Atlas lekarstvennyh rastenij Rossii. Pod red. V.A. Bykova. M., 2006; s. 333–4 [Atlas lekarstvennykh rastenii Rossii. Pod red. V.A. Bykova. M., 2006; s. 333–4 (in Russ.)].
  4. Astaf'ev B.A. Ocherki po obschej patologii gel'mintozov u cheloveka. M.: Meditsina, 1975; 205 s. [Astaf’ev B.A. Ocherki po obshchei patologii gel’mintozov u cheloveka. M.: Meditsina, 1975; 205 s. (in Russ.)].
  5. Chebyshev N.V., Bogojavlenskij Ju.K., Grishina E.A. Gel'mintozy: organo-sistemnye protsessy v ih patogeneze. M.: Meditsina, 1998; 236 s. [Chebyshev N.V., Bogoyavlenskii Yu.K., Grishina E.A. Gel’mintozy: organo-sistemnye protsessy v ikh patogeneze. M.: Meditsina, 1998; 236 s. (in Russ.)].
  6. Arhipov I.A. Antigel'mintiki: farmakologija i primenenie. M., 2009 [Arkhipov I.A. Antigel’mintiki: farmakologiya i primenenie. M., 2009 (in Russ.)].
  7. Kosova I.V., Milehina N.V., Terehova L.V. i dr. Ratsional'naja farmakoterapija zabolevanij organov pischevarenija: uchebno-metodicheskoe posobie po klinicheskoj farmakologii. M: RUDN, 2015; 62 s. [Kosova I.V., Milekhina N.V., Terekhova L.V. et al. Ratsional’naya farmakoterapiya zabolevanii organov pishchevareniya: uchebno-metodicheskoe posobie po klinicheskoi farmakologii. M: RUDN, 2015; 62 s. (in Russ.)].
  8. Turkina M.Ja., Pecherina T.V. Zosterin – novyj sorbent dlja efferentnoj terapii. Efferentnaja terapija. 2007; 13 (4): 39–44 [Turkina M.Ya., Pecherina T.V. Zosterin – a new sorbent for efferent therapy. Efferentnaya terapiya. 2007; 13 (4): 39–44 (in Russ.)].
  9. Khasina E.I., Kolenchenko E.A., Sgrebneva M.N. et al. Antioxidant Activities of a Low Etherified Pectin from the Seagrass Zostera marina. Russian Journal of Marine Biology. 2003; 29 (4): 259–61.
  10. Chernysheva E.S., Tselykovskij V.A. Mohov A.V. i dr. Gel'mintozy v hirurgicheskoj gastroenterologii. Vestnik hirurgicheskoj gastroenterologii. 2012; 4: 76–9 [Chernysheva E.S., Ctelykovsky V.A., Mohov A.V. et al. Helminthosis in the surgical gastroenterology. Vestnik khirurgicheskoi gastroenterologii. 2012; 4: 76–9 (in Russ.)].
  11. Makedonskaja T.P. Sochetannoe primenenie glutamina i pektina v lechenii sindroma kishechnoj nedostatochnosti pri peritonite. Avtoref. dis. ... kand. med. nauk. M., 2003; 157 s. [Makedonskaya T.P. Sochetannoe primenenie glutamina i pektina v lechenii sindroma kishechnoi nedostatochnosti pri peritonite. Avtoref. dis. ... kand. med. nauk. M., 2003; 157 s. (in Russ.)].
  12. Kirkovskij V.V. Detoksikatsionnaja terapija pri peritonite. Minsk: Polifakt-Al'fa, 1997; s. 68–70 [Kirkovskii V.V. Detoksikatsionnaya terapiya pri peritonite. Minsk: Polifakt-Al’fa, 1997; s. 68–70 (in Russ.)].
  13. Briskin B.S., Demidov D.A. Evoljutsija enterosorbtsii v lechenii hirurgicheskogo endotoksikoza. Mezhdunarodnyj meditsinskij zhurnal. 2004; 4: 86–8 [Briskin B.S., Demidov D.A. Evolution of enterosorption in treatment of endotoxicosis. Mezhdunarodnyi meditsinskii zhurnal. 2004; 4: 86–8 (in Russ.)].
  14. Patent №218636 RF ot 27.07. 2002 [Patent №218636 RF ot 27.07. 2002 (in Russ.)].
  15. Registr lekarstvennyh sredstv Rossii RLS [Data obraschenija 20.01.2020] [Registr lekarstvennykh sredstv Rossii RLS (in Russ.)]. URL: https://www.rlsnet.ru/tn_index_id_24865.htm
  16. Registr lekarstvennyh sredstv Rossii RLS [Data obraschenija 20.01.2020] [Registr lekarstvennykh sredstv Rossii RLS (in Russ.)]. URL: https://www.rlsnet.ru/tn_index_id_5646.htm