SKIN TOXICITY OF CHEMOTHERAPY AND CUTANEOUS MANIFESTATIONS OF CHRONIC GRAFT VERSUS HOST REACTION. THE PRINCIPLES OF NON-DRUG CORRECTION OF SKIN LESIONS

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Issue: 
8
Year: 
2017

Professor N. Potekaev (2), MD; P. Trakhtman(1), MD; O. Passokhina (2); E. Shuginina (3), Candidate of Medical Sciences; L. Ivanova (4), PhD 1-Dmitry Rogachev National Research-and-Clinical Center for Pediatric Hematology, Oncology, and Immunology, Moscow 2-N.I. Pirogov Russian National Research Medical University, Moscow 3-Peoples’ Friendship University of Russia, Moscow 4-ZAO «Oberon», Moscow

The paper considers the specific features of changes in chronic graft versus host reaction and the toxic effects of chemotherapeutic agents used to treat hematological cancer and hematological patients prior to hematopoietic stem cell transplantation during conditioning and before. Methods for correcting the detected changes are proposed.

Keywords: 
skin toxicity
chronic graft versus host reaction (cGVHR)
cutaneous manifestations of cGVHR
diagnosis of cGVHR
extensive cGVHR
circumscribed cGVHR
dermatoscopy
capillaroscopy
correction of skin manifestations of cGVHR
skin toxicity



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