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THE FEATURES OF ACID PRODUCTION AND THE PATHOGENESIS OF ASSOCIATED COMPLICATIONS IN PATIENTS WITH PYLORIC AND PREPYLORIC ULCERS

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Issue: 
7
Year: 
2017

A. Cherepanin (2), MD; Professor O. Antonov (1), MD; Professor M. Negrebov (1), MD; A. Rybalchenko (1); R. Sherov (1) 1-I.M. Sechenov First Moscow State Medical University (Sechenov University) 2-ZAO MEDSI Companies Group, Moscow

Acid production was comparatively analyzed in 150 patients with peptic disease with type III duodenal and gastric ulcers according to the classification developed by H. Johnson. Patients with duodenal ulcers were found to have a definite individual rhythm of daily intragastric acidity with its maximum during nocturnal hours. The features of gastric juice secretion were established depending on the location of ulcerative substrate. The paper shows a pathogenetic rationale for the use of antisecretory drugs in the treatment of duodenal ulcers and the need for the further improvement of a management algorithm for pyloric and prepyloric ulcers.

Keywords: 
gastroenterology
pyloric ulcers
prepyloric ulcers
acid production



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References: 
  1. Leonova M.V., Belousov Ju.B. N2-blokatory v gastroenterologicheskoj praktike / M., 1996; s. 62.
  2. Naumov B.A., Kotaev A.Ju. Hirurgicheskoe lechenie oslozhnennyh piloricheskih i prepiloricheskih jazv zheludka / M., 1994; 143 s.
  3. Pantsyrev Ju.M., Mihalev A.I., Fedorov E.D. Hirurgicheskoe lechenie probodnyh i krovotochaschih piloroduodenal'nyh jazv // Hirurgija. – 2003; 3: 43–9.
  4. Pantsyrev Ju.M., Mihalev A.I., Fedorov E.D. i dr. Hirurgicheskoe lechenie jazvennyh gastroduodenal'nyh krovotechenij. 1-j Kongress moskovskih hirurgov «Neotlozhnaja i spetsializirovannaja hirurgicheskaja pomosch'». Tezisy dokladov. M., 19–21.05.2005; s. 27–8.
  5. Pantsyrev Ju.M., Chernjakevich S.N., Mihalev A.I. Hirurgicheskoe lechenie jazvennogo piloroduodenal'nogo stenoza // Hirurgija. – 2003; 2: 18–21.
  6. Tolstokorov A.S., Strelkov A.S., Dergunova S.A. Hirurgicheskaja taktika pri gastroduodenal'nyh krovotechenijah, sochetannyh s drugimi oslozhnenijami jazvennoj bolezni. 1-j Kongress moskovskih hirurgov «Neotlozhnaja i spetsializirovannaja hirurgicheskaja pomosch'». Tezisy dokladov. M., 19–21.05.2005; s. 33–4.
  7. Shalomitskaja A.I. Individual'naja antisekretornaja terapija duodenal'nyh jazv pri monitoringe vnutrizheludochnogo rN // Eksperim. i klin. gastroenterol. – 2003; 1: 119–20.
  8. Muller C., Martinoli S. Die Proximal-Selektive Vagotomie in der Behandlung der Gastroduodenalen UlcusKrankheit / Berlin, Heidelberg, New-York: Springel-Vergal, 1985.
  9. Taylor T., Mac Leod D., Gunn A. et al. Anterior lesser curve seromyotomy and posterior truncal vagotomy in the treatment of chronic duodenal ulcer // Lancet. – 1982; 16: 846–8.