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A. Melerzanov (1), MD, PhD; Professor A. Penaev (3), MD; A. Mishra (1); S. Toski (2), MD 1-Moscow Institute of Physics and Technology 2-Dell’ Angelo Hospital, Mestre, Italy 3-Doctor Penaev Clinic, Moscow

The specific feature of a new liposuction technology for small adipose tissue volumes is its cytopreserving effect. No pronounced destructive action of low-frequency ultrasound on adipose tissue mesenchymal stem cells allows the use of this technology not only for liposculpture, but also for obtaining viable stem cells.

cytopreserving liposuction
mesenchymal stem cells
low-frequency ultrasound

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  1. Zhu M., Mizuno H. et al. Multilineage cells from human adipose tissue: implications for cell-based therapies // Tissue Eng. – 2001; 7 (2): 211–28.
  4. Gaur M., Dobke M., Lunyak V. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging // Int. J. Mol. Sci. – 2017; 18 (1): E208. DOI: 10.3390/ijms18010208.
  7. Mizuno H., Itoi Y., Kawahara S. et al. In vivo adipose tissue regeneration by adipose-derived stromal cells isolated from GFP transgenic mice // Cells Tissues Organs. – 2008; 187: 177–85. DOI: 10.1159/000110805.
  8. Chen C. Replacing Like with Like: Clarifying Fat Grafting’s Role in Breast Reconstruction. Published on September 29, 2014.
  9. Luan A., Duscher D., Whittam A. et al. Cell-Assisted Lipotransfer Improves Volume Retention in Irradiated Recipient Sites and Rescues Radiation-Induced Skin Changes // Stem Cells. – 2016; 34 (3): 668–73.
  10. Sheng Huang, Weiliang Zhao, Zihua Wang et al. PMCID: Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review) // Mol. Med. Rep. – 2016; 13 (2): 1063–9. DOI: 10.3892/mmr.2015.4682.
  11. Bian Y., Deng C., Li W. et al. A Comparative Study on the Biological Characteristics of Human Adipose-Derived Stem Cells from Lipectomy and Liposuction // PLoS One. – 2016; 11 (9): e0162343. DOI: 10.1371/journal.pone.0162343.
  12. Muscari C., Bonafè F., Fiumana E. et al. Comparison between stem cells harvested from wet and dry lipoaspirates // Connect. Tissue Res. – 2013; 54 (1): 34–40. DOI: 10.3109/03008207.2012.717130.
  13. Keck M., Kober J., Riedl O. et al. Power assisted liposuction to obtain adipose-derived stem cells: impact on viability and differentiation to adipocytes in comparison to manual aspiration // Plast. Reconstr. Aesthet. Surg. – 2014; 67 (1): e1–8. DOI: 10.1016/j.bjps.2013.08.019.
  14. Yildiz K., Taşli P., Şahin F. et al. Comparison of Cellular Alterations in Fat Cells Harvested With Laser-Assisted Liposuction and Suction-Assisted Liposuction // J. Craniofac. Surg. – 2016; 27 (3): 631–5. DOI: 10.1097/SCS.0000000000002589.
  15. Shim Y., Zhang R. Literature Review to Optimize the Autologous Fat Transplantation Procedure and Recent Technologies to Improve Graft Viability and Overall Outcome: A Systematic and Retrospective Analytic Approach // Aesthetic. Plast. Surg. – 2017; DOI: 10.1007/s00266-017-0793-3.
  16. Duscher D., Atashroo D., Maan Z. et al. Ultrasound-Assisted Liposuction Does Not Compromise the Regenerative Potential of Adipose-Derived Stem Cells // Stem Cells Transl. Med. – 2016; 5 (2): 248–57. DOI: 10.5966/sctm.2015-0064.
  17. Palumbo P., Cinque B., Miconi G. et al. Biological effects of low frequency high intensity ultrasound application on ex vivo human adipose tissue // Int. J. Immunopathol. Pharmacol. – 2011; 24 (2): 411–22.
  18. Yagi H., Soto-Gutierrez A., Navarro-Alvarez N. et al. Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1 // Mol. Ther. – 2010; 18 (10): 1857–64.