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Professor O. Tkacheva (1), MD; E. Mkhitaryan (1, 2), Candidate of Medical Sciences; T. Manevich (1), Candidate of Medical Sciences 1-Russian Gerontology Research and Clinical Center, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow 2-I.M. Sechenov First Moscow State Medical University

Cognitive impairment (CI) is one of the most common disorders among elderly and senile people. The prevalence of all CIs no dementia in people aged over 80 years is as high as 40 to 80% according to some data. The paper gives an algorithm for the diagnosis of CI and for the management of these patients.

cognitive functions
cognitive impairment no dementia
basic and symptomatic therapy

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  1. Zaharov V.V. Kognitivnye rasstrojstva bez dementsii: klassifikatsija, osnovnye prichiny i lechenie // Effektivnaja farmakoterapija. Nevrologija. – 2016; 1 (1): 22–30.
  2. Zaharov V.V. Vozrastnye kognitivnye narushenija. Pod red. N.N. Jahno / M.: Servier, 2004; 12 s.
  3. Zaharov V.V., Voznesenskaja T.G. Nervno-psihicheskie narushenija: Diagnosticheskie testy / M.: MEDprecs-inform, 2014; 320 s.
  4. Levin O.S. Diagnostika i lechenie dementsii v klinicheskoj praktike / M.: MEDpress-inform, 2010; 256 s.
  5. Jahno N.N. Kognitivnye rasstrojstva v nevrologicheskoj klinike // Nevrol. zhurn. –2006; 11 (Pril. 1): 4–12.
  6. Jahno N.N., Zaharov V.V., Lokshina A.B. i dr. Dementsii: Rukovodstvo dlja vrachej. 3-e izd. / M.: MEDprecs-inform, 2011; 264 s.
  7. Jahno N.N., Zaharov V.V., Lokshina A.B. Narushenija pamjati i vnimanija v pozhilom vozraste // Zhurn. nevrol. i psihiat. – 2006; 106 (2): 58–62.
  8. Jessen F., Amariglio R., van Boxtel M. et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease // Alzheimer’s Dement. – 2014; 10 (6): 844–52.
  9. Petersen R., Touchon J. Consensus on mild cognitive impairment. Research and practice in Alzheimer's disease // E.A.D.C./A.D.C.S. Joint meetihg. – 2005; 10: 24–32.
  10. Dementia: a public health priority / WHO Library Cataloguing-in-Publication Data, 2012.
  11. Zaharov V.V. Vserossijskaja programma issledovanij epidemiologii i terapii kognitivnyh rasstrojstv v pozhilom vozraste (PROMETEJ) // Nevrol. zhurn. – 2006; 11 (2): 27–32.
  12. Luck T., Riedel-Heller S., Kaduszkiewicz H. et al Mild Cognitive Impairment in General Rractice: Age-Specific Prevalence and Correlate Results from the German Study on Ageing, Cognition and dementia in Primary Care Patients (AgeCoDe) // Dement. Geriatr. Cogn. Disord. – 2007; 24: 307–16.
  13. Moatassema A., Mousa S., Khater M. et al. Prevalence of mild cognitive impairment among older adults living in Mansoura city // Egypt Middle East Current Psychiatry. – 2012; 19 (1): 3–7.
  14. Huntzinger J., Rosse R., Schwartz B. et al. Clock drawing in the screening assessment of cognitive impairment in an ambulatory care setting: a preliminary report // Gen Hosp. Psychiatry. – 1992; 14 (2): 142–4.
  15. Borson S., Scanlan J., Chen P. et al. The Mini-Cog as a screen for dementia: Validation in a population-based sample // J. Am. Geriatr. Soc. – 2003; 51: 1451–4.
  16. Folstein M., Folstein S., McHugh P. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician // J. Psychiatr. Res. – 1975; 12: 189–98.
  17. Nasreddine Z., Phillips N., Bédirian V. et al. Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment // J. Am. Geriatr. Soc. – 2005; 53: 695–9.
  18. Matsunaga S., Kishi T., Iwata N. Memantine Monotherapy for Alzheimer’s Disease: A Systematic Review and Meta-Analysis // PLoS One. – 2015; 10 (4): e0123289.