ETIOLOGICAL DIAGNOSIS OF DIET-INDUCED OBESITY IN ADOLESCENTS

Download full text PDF
Issue: 
12
Year: 
2016

Professor V. Popova, MD; Professor A. Kozhin, MD; Yu. Megid; E. Romanova, Candidate of Medical Sciences Rostov Research Institute of Obstetrics and Pediatrics, Rostov-on-Don

The paper presents the results of examining 2 groups of boys with varying degrees of diet-induced obesity and with signs of functionally delayed sexual development (FDSD). A correlation was found between the morning urine levels of chromium and manganese and the degree of obesity. Furthermore, children with deficiency of the above chemical elements had signs of hypoinsulinemia and hyperglycemia besides obesity. In the absence of signs of microelementosis, elevated leptin levels may trigger obesity concurrent with FDSD. These findings provide a rationale for the modification of an algorithm for diagnostic screening of young obese people and for etiotropic therapy.

Keywords: 
endocrinology
obesity
microelementosis
diagnosis



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Verbitskaja O.G., Popova V.A., Afonin A.A. i dr. Kliniko-diagnosticheskoe znachenie opredelenija leptina i androgenov u mal'chikov i podrostkov s ozhireniem // Med. vestn. juga Rossii. – 2013; 2: 37–43.
  2. Kozhin A.A. Popova V.A. Daurbekova M.A. Mikroelementozy kak prediktory zaderzhki polovogo razvitija u mal'chikov-podrostkov // Mezhdunar. zhurn. eksperim. obrazovanija. – 2014; 3: 49–55.
  3. Verbitskaja O.G., Kozhin A.A., Popova V.A. Zaderzhka polovogo razvitija u mal'chikov-podrostkov: mehanizmy i etiologicheskaja diagnostika // Vrach. – 2014; 12: 78–83.
  4. Oberlis D., Harland B., Skal'nyj A.V. Biologicheskaja rol' makro i mikroelementov u cheloveka i zhivotnyh / SPb: Nauka, 2008; 544 s.
  5. Popova V., Kozhin A., Daurbekova M. Etiological diagnostics of the boy's functional retenshion of sexual development. 5th Congress of the European academy of Paediatric Societies, Spain, Barselona, October 17–20, 2014; A 256.
  6. Dedov I.I., Mel'nichenko G.A. Ozhirenie. Rukovodstvo dlja vrachej / M., 2006; 456 s.
  7. Chagaj N.B. Tumilovich L.G. Gevorkjan M.A. Leptin i reproduktivnye organy – misheni // Problemy reproduktsii. – 2008; 3: 7–13.
  8. Griffin D., Oheda S. Fiziologija endokrinnoj sistemy / M.: Binom. Laboratornaja diagnostika, 2008; 496 s.
  9. Smirnov A.N. Endokrinnaja reguljatsija. Biohimicheskie i fiziologicheskie aspekty: ucheb.posobie. Pod red. V.A.Tkachuka / M.: GEOTAR-Media, 2009; 368 s.
  10. Prasad A. Discovery of human zinc deficiency: 50 years later // Trace Elem. Med. Biol. – 2012; 206: 66–9.
  11. Skal'nyj A.V. Himicheskie elementy v fiziologii i ekologii cheloveka / M.: ONIKS 21 vek, 2004; 218 s.
  12. Mistry H., Broughtan P., Patson I. Selenium in reproductive health // Am. J. Obstet. Gynecol. – 2012; 206 (1): 21–30.
  13. Vinsent J. Elucidating a biological role for chromium a molecular level // Acc. Chem. Res. – 2000; 33: 503–10.