The Journal is included in Russian and International Library and Abstract Databases
Russain Science Index (Russia)
EBSCO
DOI Registration Agency (USA)

TREATMENT OF MILD AND MODERATE MAJOR DEPRESSIVE DISORDER WITH VALDOXANE (AGOMELATINE) IN PATIENTS WITH CARDIOVASCULAR DISORDERS: RESULTS OF THE NATIONAL OBSERVATIONAL MULTICENTER STUDY «PULSE»

Download full text PDF
Issue: 
3
Year: 
2015

V. Medvedev, Candidate of Medical Sciences People’s Friendship University of Russia

The results of National observational multicenter study «PULSE» show that cardiologists can successfully detect such depressive symptoms as hypothymia, anhedonia, asthenia, sleep disturbances, cognitive impairments. High therapeutic efficacy and tolerability of Valdoxane (Agomelatine) has been shown in standard dosing in treatment of mild and moderate depressive disorders in cardiovascular patients in Russian Federation. On the top of combined therapy main hemodynamic indices improve or stay stable.

Keywords: 
cardiovascular disorders
depression
agomelatine



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Avedisova A.S., Zaharova K.V., Marachev M.P. Rezul'taty observatsionnoj programmy DZhAZ: Effektivnost' preparata agomelatin (Val'doksan)pri lechenii patsientov s trevozhnoj depressiej v ramkah bol'shogo depressivnogo rasstrojstva // Psihiat. i psihofarmakoter. – 2013; 6: 14–22.
  2. Bochkarev M.V., Ragozin O.N., Frosin S.A. Primenenie Val'doksana ubol'nyh serdechno-sosudistymi zabolevanijami s narushenijami sna i depressiej v uslovijah Severnogo regiona Rossii // Psihich. rasstrojstva v obschejmeditsine. – 2013; 4: 69–73.
  3. Zlokazova M.V. Opyt primenenija Val'doksana pri lechenii umerennyhi tjazhelyh depressivnyh rasstrojstv nepsihoticheskogo urovnja u ambulatornyh patsientov // Psihiat. i psihofarmakoter. – 2009; 4: 39–41.
  4. Ivanov S.V. Val'doksan (agomelatin) pri terapii umerennyh i tjazhelyh form depressii nepsihoticheskogo urovnja v ambulatornoj i gospital'noj praktike (rezul'taty Rossijskogo mul'titsentrovogo issledovanijaHronos) // Psihiat. i psihofarmakoter. – 2009; 6: 14–7.
  5. Medvedev V.E. Primenenie Val'doksana (agomelatin) v kombiniro-vannoj terapii umerenno vyrazhennyh i tjazhelyh depressij nepsihoticheskogo urovnja. // Zhurn. nevrol. i psihiat. im. S.S. Korsakova. – 2012; 5 (1):37–40.
  6. Medvedev V.E., Epifanov A.V. Innovatsionnyj metod terapii depressij u patsientov s ishemicheskoj bolezn'ju serdtsa // Obozrenie psihiat. i med.psihol. im. V.M. Behtereva. – 2010; 3: 31–6.
  7. Medvedev V.E., Martynov S.E., Zverev K.V. i dr. Psihosomaticheskiezabolevanija v kardiologii (tipologija i kliniko-dinamicheskie harakteristiki) // Psihiat. i psihofarmakoter. – 2012; 4: 34–41.
  8. Medvedev V.E., Chobanu I.K., Frolova V.I. i dr. Effektivnost' psihofarmakoterapii i psihoterapii u patsientov s serdechno-sosudistymi zabolevanijami // Arhiv' vnutrennej meditsiny. – 2013; 5: 61–6.
  9. Oganov R.G., Ol'binskaja L.I., Smulevich A.B. i dr. Depressija v obschesomaticheskoj praktike: rezul'taty programmy KOMPAS/Serv'e, 2004.
  10. Samushija M.A., Mjasnikova L.K. Val'doksan (agomelatin) v terapiidepressivnyh rasstrojstv u patsientov s onkologicheskimi zabolevanijamiorganov zhenskoj reproduktivnoj sistemy // Psihich. rasstrojstva v obschejmeditsine. – 2012; 3: 21–5.
  11. Statsenko M.E., Shilina N.N., Turkina S.V. Effektivnost' primenenijaVal'doksana v vosstanovitel'nyj periode infarkta miokarda u patsientov ssaharnym diabetom tipa 2 i trevozhno-depressivnymi rasstrojstvami //Psihiat. i psihofarmakoter. – 2012; 6: 8–13.
  12. Tsygankov B.D., Jaltonskaja A.V., Filippskih S.V. Val'doksan (agomelatin) v terapii tjazhelyh i umerennyh depressij nepsihoticheskogo urovnja(rezul'taty observatsionnogo issledovanija) // Obozrenie psihiat. i med.psihol. im. V.M. Behtereva. – 2011; 1: 37–40.
  13. Jahno N.N., Voznesenskaja T.G. Effektivnost' i perenosimost'Val'doksana (agomelatin) pri terapii legkih i umerennyh depressivnyhrasstrojstv v nevrologicheskoj praktike. Rezul'taty Rossijskogo mul'titsentrovogo issledovanija KAMERTON) // Nevrol. zhurn. – 2012; 1: 43–9.
  14. Stahl St. Valdoxan (agomelatine): a novel antidepressant. The Role ofcircadian rhythms in the treatment of depression / Arbor Scientia, 2011.