Analysis of the efficiency and safety of using the slow-release calcium channel blocker nifedipine as a tocolytic drug in pregnant women with preterm labor
DOI: https://doi.org/10.29296/25877305-2021-01-02
Issue:
1
Year:
2021
Preterm labor (PL) remains one of the major problems of modern obstetrics all over the world, which
is due to the unresolved issues concerning etiology, pathogenesis, clinical presentation, diagnosis, and
rational pharmacotherapy. PL complications are the main cause of neonatal death worldwide; with the
surviving infants facing the risk of serious neonatal complications and long-term disability. In the course
of prioritization work, the WHO has placed PL in the top 10 research priorities for the period up to 2025.
The investigations aimed at preventing PL and reducing perinatal mortality are also a key component of the
UN global strategy for sustainable development until 2030. The development and introduction of technologies
for personalized medicine are ways to optimize tocolytic therapy in pregnant women with PL, which are
regulated in the Russian Strategy for the Development of Medical Science until 2025.
Keywords:
obstetrics and gynecology
preterm labor
tocolysis
nifedipine
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