THE ROLE OF MOLECULAR GENETIC METHODS IN THE DETECTION OF TUBERCULOSIS IN THE GENERAL HEALTHCARE NETWORK

DOI: https://doi.org/10.29296/25877305-2022-10-07
Issue: 
10
Year: 
2022

A. Kolesnikova(1), Professor B. Borodulin(1), MD; D. Kudlay(2, 3), Corresponding Member of RAS, MD Associate Professor L. Povalyaeva(1), Candidate of Medical Sciences
1-Samara State Medical University, Ministry of Health of Russia
2-I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
3-NRC Institute of Immunology FMBA of Russia, Moscow

The problem of timely tuberculosis (TB) detection remains relevant even when its epidemic situation improves. Despite a well-organized preventive examination system, many TB cases are detected when a patient visits the general medical network. This problem is most often faced by a pulmonologist especially at the stage of inpatient treatment. The implementation of the diagnostic minimum in the inpatient pulmonology department is a routine practice. When communicating with each pulmonology patient, the physician should be alert to TB when collecting historical data, examining, planning an examination, by obligatorily using the current diagnostic methods. This review considers the role of a pulmonologist in detecting TB when patients visit the general medical network. A rationale is provided for the necessity of including rapid molecular genetic technologies into the standard diagnostic minimum in order to detect Mycobacterium tuberculosis DNA in patients at risk for TB.
Keywords: 
phthisiology
tuberculosis
pulmonologist
Mycobacterium tuberculosis
diagnostic minimum
general medical network
tuberculosis risk groups

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