Comparative characteristics of social risk factors for local forms of tuberculosis in children: at the peak of the incidence rate and during the period of improving the epidemiological situation

DOI: https://doi.org/10.29296/25877305-2022-09-16
Issue: 
9
Year: 
2022

E. Amosova(1), Candidate of Medical Sciences; G. Poretskova(1), MD; Professor
G. Santalova(1), MD; D. Kudlay(2, 3), Corresponding Member of RAS, MD;
E. Eremenko(1), Candidate of Medical Sciences
1-Samara State Medical University, Ministry of Health of Russia
2-I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
3-NRC Institute of Immunology FMBA of Russia, Moscow

Amosova E., Poretskova G., Santalova G. , Kudlay D., Eremenko E., A social risk factor (RF) is one of the main RFs for tuberculosis (TB). The incidence of TB in children depends on that in adults. TB is a social disease, one of whose signs is a direct association with living conditions. Objective. To compare social RFs for local forms of TB in children over time at the incidence peak (2006–2007) and during the period of improving the epidemiological situation (2020–2021). Subjects and methods. To identify social RFs for TB, medical records were analyzed and questionnaire survey was done in children aged 12–17 years and adolescents in varying educational establishments who were treated for respiratory TB (60 patients in 2006–2007 and 32 in 2020–2021). The questionnaire contained 37 questions concerning the general characteristics of a child, his/her family composition, and economic, living, and nutritional conditions. The findings were comparatively assessed. Results. The analysis showed that living in a single parent family remained one of the social RFs for TB. At the same time, social and living conditions had substantially improved: the number of families living in comfortable apartments had grown; and the number of children having a separate room had increased. There was the persistent stress influence on children, which was associated with bad parenting habits, unbalanced diet, and an unsatisfactory way of life, which causes psychological problems in the family.

Keywords: 
phthisiology
tuberculosis
adolescents
social risk factors
Mycobacterium tuberculosis infection
local forms of tuberculosis



References: 
  1. Borodulina E.V., Borodulina E.A., Gladunova E.P. et al. Medico-social characteristics of newly diagnosed patients with tuberculosis. Meditsinskii al’yans. 2018; 3: 41–6 (in Russ.).
  2. Aksenova V.A., Sterlikov S.A., Belilovskiy E.M. et al. Epidemiology of tuberculosis in children. Current problems of health care and medical statistics. 2019; 1: 8–43 (in Russ.). DOI: 10.24411/2312-2935-2019-10002
  3. Borodulina Ye.A., Amosova Ye.A., Borodulin B.Ye. et al. Risk factors for tuberculosis in children. RMJ. 2009; 1: 15–6 (in Russ.).
  4. Amosova E.A., Borodulina E.А., Uraksina M.V. Peculiarities of early diagnosis of tuberculosis infection and indicators of children’s health during adaptation to school. Pediatria n.a. G.N. Speransky. 2020; 99 (3): 130–3 (in Russ.). DOI: 10.24110/0031-403X-2020-99-3-130-133
  5. Nechaeva O.B. Tuberculosis in children in Russia. Tuberculosis and Lung Diseases. 2020; 98 (11): 12–20 (in Russ.). DOI: 10.21292/2075-1230-2020-98-11-12-20
  6. Aksenova V.A., Levi D.T., Aleksandrova N.V. et al. Pediatric TB: Modern Methods for Prevention and Early Diagnostics. Doctor.Ru. 2017; 15 (144): 9–15 (in Russ.).
  7. Starshinova А.А., Kudlay D.A., Dovgalyuk I.F. et al. Efficacy of new methods of tuberculosis infection immunodiagnostics in the Russian Federation. Pediatria n.a. G.N. Speransky. 2019; 98 (4): 229–35 (in Russ.). DOI: 10.24110/0031-403X-2019-98-4-229-235
  8. Kudlay D.A., Starshinova A.A., Dovgalyuk I.F. Recombinant tuberculosis allergen: 10 years of experience with the test in children and adolescents in the Russian Federation (meta analysis data). Pediatria n.a. G.N. Speransky. 2020; 99 (3): 121–9 (in Russ.). DOI: 10.24110/0031-403X-2020-99-3-121-129
  9. Eremenko E.P., Borodulina E.A., Sergeeva I.A. et al. Recombinant in vitro test T-SPOT.TB as a screening method for early diagnosis of tuberculosis infection. Tuberculosis and Lung Diseases. 2020; 98 (4): 48–52 (in Russ.). DOI: 10.21292/2075-1230-2020-98-4-48-52
  10. Borodulina E., Amosova E., Borodulin B. et al. Diagnostics with tuberculin in children in modern conditions. Current Pediatrics. 2010; 9 (1): 70–4 (in Russ.).
  11. Borodulina E.A., Akhmerova T.E., Yeremenko E.S. et al. Features of diagnostics of tuberculosis in children using Diaskintest. Epidemiology and Vaccinal Prevention. 2014; 6 (79): 51–5 (in Russ.).
  12. Aksenova V.A., Klevno N.I., Baryshnikova L.A. et al. Vyyavlenie tuberkuleza i taktika dispansernogo nablyudeniya za litsami iz grupp riska s ispol’zovaniem rekombinantnogo tuberkuleznogo allergena – Diaskintest®. Metodicheskie rekomendatsii. M.: Pervyi MGMU im. I.M. Sechenova, 2011; 12 р. (in Russ.).
  13. Shubina A.T., Borodulina E.A., Kudlay D.A. et al. Test with recombinant tuberculosis allergen (Diaskintest®) in the diagnosis of pulmonary tuberculosis in pulmonological practice. Pulmonologiya. 2022; 32 (4): 576–84 (in Russ.). DOI: 10.18093/0869-0189-2022-32-4-576-584
  14. Borodulina E.A., Borodulin B.E. Differential diagnosis of postvaccinal and infectious tuberculin allergy in children with atopic diseases. Problemy tuberkuleza i boleznei legkikh. 2006; 1: 9 (in Russ.).
  15. Eremenko E.P., Borodulina E.A., Amosova E.A. HIV infection as a risk factor of tuberculosis in children. Tuberculosis and Lung Diseases. 2017; 95 (1): 18–21 (in Russ.). DOI: 10.21292/2075-1230-2017-95-1-18-21
  16. Golovanova M.N., Chelnokova O.G. Assessment of the epidemiological hazard of tb infection nidi in the territory using the original computer programme. CTRI Bulletin. 2021; 4: 15–25 (in Russ.). DOI: 10.7868/S2587667821040026
  17. Borodulina E.A., Amosova E.A., Gribova V.V. et al. «Avtomatizirovannaya programma formirovaniya grupp riska po tuberkulezu v praktike pediatra». Svidetel’stvo o gosudarstvennoi registratsii programmy dlya EVM No2022665907 ot 23.08.2022 (in Russ.).