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A method for pharmacological correction of coronary circulatory disorders in the presence of the myocardial bridge in the coronary artery

DOI: https://doi.org/10.29296/25877305-2021-09-12

Yu. Kostyamin, Candidate of Medical Sciences; T. Tverdokhleb; O. Naletova, MD M. Gorky Donetsk
National Medical University, Donetsk, Donetsk People’s Republic/Ukraine

A myocardial bridge is a congenital anomaly in which a segment of the coronary artery tunnels under the bridge of the overlapping myocardium. This causes the vessel to contract during systole, resulting in hemodynamic changes that can be associated with angina pectoris, myocardial ischemia, acute coronary syndrome, left ventricular dysfunction, arrhythmias, and sudden cardiac death. Beta-adrenoblockers and calcium channel blockers are the first-line therapy to eliminate the symptoms of a tunneled coronary artery. Surgical tactics (myotomy, intracoronary stenting, or aortocoronary bypass surgery) is indicated for refractory symptoms. A method for pharmacological correction of a verified myocardial bridge in the coronary artery is presented in our clinical case.

myocardial bridge
angina pectoris
intramyocardial coronary artery segment

  1. Rogers I.S., Tremmel J.A., Schnittger I. Myocardial bridges: Overview of diagnosis and management. Congenit Heart Dis. 2017; 12 (5): 619–23. DOI: 10.1111/chd.12499
  2. Corban M.T., Hung O.Y., Eshtehardi P. et al. Myocardial bridging: contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies. J Am Coll Cardiol. 2014; 10; 63 (22): 2346–55. DOI: 10.1016/j.jacc.2014.01.049
  3. Tarantini G., Migliore F., Cademartiri F. et al. Left anterior descending artery myocardial bridging a clinical approach. J Am Coll Cardiol. 2016; 68 (25): 2887–99. DOI: 10.1016/j.jacc.2016.09.973
  4. Teragawa H., Oshita C., Ueda T. The myocardial bridge: potential influenceson the coronary artery vasculature. Clin Med Insights Cardiol. 2019; 13: Published online. DOI: 10.1177/1179546819846493
  5. Mok S., Majdalany D., Pettersson G.B. et al. Extensive unroofing of myocardial bridge: A case report and literature review. SAGE Open Med Case Rep. 2019; 7: Published online. DOI: 10.1177/2050313X18823380
  6. Rovai D., Di Bella G., Pingitore A. Myocardial bridging: a review with emphasis on electrocardiographic findings. Ann Noninvasive Electrocardiol. 2015; 20 (2): 103–7. DOI: 10.1111/anec.12242
  7. Murtaza G., Mukherjee D., Gharacholou S.M. An Updated Review on Myocardial Bridging. Cardiovasc Revasc Med. 2020; 21 (9): 1169–79. DOI: 10.1016/j.carrev.2020.02.014
  8. Kabak S.L., Mel'nichenko Ju.M., Gordionok D.M. i dr. Miokardial'nye mostiki i obstruktivnyj ateroskleroz venechnyh arterij. Izvestija Natsional'noj akademii nauk Belarusi. Serija meditsinskih nauk. 2020; 17 (1): 38–48 [Kabak S.L., Melnichenko Yu.M., Gordionok D.M. et al. Myocardial bridges and obstructive coronary atherosclerosis. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2020; 17 (1): 38–48 (in Russ.)]. DOI: 10.29235/1814-6023-2020-17-1-38-48
  9. Bokerija L.A., Suhanov S.G., Sternik L.I. i dr. Miokardial'nye mostiki. M.: NTsSSH im. A.N. Bakuleva RAMN, 2013; 158 s. [Bokeriya L.A., Sukhanov S.G., Sternik L.I. et al. Miokardial’nye mostiki. M.: NTsSSKh im. A.N. Bakuleva RAMN, 2013; 158 s. (in Russ.)].