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CLINICAL EFFECTIVENESS OF THE MEDICINE ALLERGOFERON IN THE TREATMENT OF INTERMITTENT RHINOCONJUNCTIVITIS IN PATIENTS OF DIFFERENT AGE GROUPS

DOI: https://doi.org/10.29296/25877305-2021-08-16
Issue: 
8
Year: 
2021

Professor A. Shavrin, Dr Med. Sci. Perm State Medical University named after E.A. Wagner

Objective: to assess the clinical effectiveness of the combined medicine Allergoferon (recombinant interferon alpha-2b + loratadine) in the form of gel for the treatment of allergic rhinoconjunctivitis in young and middle-aged adult patients. Materials and methods. The study included 56 patients with allergic rhinoconjunctivitis. They were divided into two groups according to their age: group 1 – 22–45 years and group 2 – 45–60 years. All patients received the combined medicine Allergoferon for the treatment of allergic rhinoconjunctivitis. The gel was applied to the skin of the upper and lower eyelids and to the nasal mucous membranes four times a day. Analysis of the treatment effectiveness was based on the assessment of the positive symptom dynamics. The symptoms were scored on a 4-point scale: 1 – not expressed; 2 – mild; 3 – moderate; 4 – severe. Results. During topical treatment with the medicine Allergoferon the severity of all evaluated symptoms was statistically significantly reduced: in 41–64% of patients already on the 7th treatment day (p

Keywords: 
pollinosis
rhinoconjunctivitis
treatment
interferon
Allergoferon
clinical effectiveness



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