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Optimization of treatment for postoperative peritonitis in patients with Stage IV cancer

DOI: https://doi.org/10.29296/25877305-2021-05-08
Issue: 
5
Year: 
2021

A.K. Antonov(1), Candidate of Medical Sciences; D. Vychuzhanin(2), Candidate of Medical
Sciences; A. Filimonyuk-Smelkov(3), MD; E. Solod(4), MD; K. Antonov(4); A.A. Antonov(4); R. Gorenkov(1, 2),
MD; Professor A. Simonova(1), MD; P. Ovchinnikova(2) (1)M.F. Vladimirsky Moscow Regional Research Clinical
Institute, Moscow (2)I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of
Health of Russia (3)Hospital of the Research Center, Russian Academy of Sciences, Chernogolovka (4)N.N.
Priorov National Medical Research Center for Traumatology and Orthopedics, Moscow

Treatment for postoperative peritonitis in patients with Stage IV cancer is an urgent and considerable problem. In the cancer patients, the mortality rate from postoperative peritonitis without treatment reaches almost 100%; that after treatment is 60-90%. Despite the currently used powerful modern antibiotics and antiseptics, the results of treatment for postoperative peritonitis, especially in advanced cancer patients, remain disappointing. Continuous search is underway toward effective methods of accompanying therapy, along with basic one, to improve the treatment of postoperative peritonitis in cancer patients and to accelerate recovery in the early postoperative period (fast-track surgery). The authors have developed a unique accompanying therapy for the surgical treatment of postoperative peritonitis in patients with Stage IV cancer, by using an adaptogenic immunomodulator (Altai extract) along with the neutral anolyte – a metastable mixture of peroxides formed during electrochemical reactions.

Keywords: 
surgery
oncology
therapy
postoperative peritonitis in patients with Stage IV cancer
Altai extract
neutral anolyte – a metastable mixture of peroxides formed during electrochemical reactions



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