Vascular endothelial dysfunction as a risk factor for excessive blood pressure elevation in response to stress in young people

DOI: https://doi.org/10.29296/25877305-2021-04-09
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Issue: 
4
Year: 
2021

E. Sklyannaya, Candidate of Medical Sciences M. Gorky Donetsk National Medical University,
Donetsk People’s Republic/Ukraine

Objective. To identify the relationship blood pressure (BP) elevation during stress and the endothelial functional in young people. Materials and methods. The investigation enrolled 980 Gorky Donetsk National Medical University students. Blood pressure was measured by the standard method 30 minutes before and during stress. Еxamination was a stressful factor. The stress-induced increase in systolic and/or diastolic blood pressures (SBP and DBP) by >25% of the initial level was considered excessive. The brachial artery reactive hyperemia test was used to evaluate endothelial function. The increase in the brachial artery diameter by 25% stress-induced increase in SBP was detected in 50 (6.5%) examined patients and that in DBP was found in 53 (6.9%). In general, there was a pathological stress-induced blood pressure reaction in 59 (7.7%) examined patients. Ninety (11.8%) examined patients demonstrated an insufficient (
Keywords: 
cardiology
hypertension
stress
endothelial dysfunction
endothelium-dependent vasodilation in the brachial artery

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