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Non-alcoholic fatty liver disease: its risk factors and it is as a risk factor

DOI: https://doi.org/10.29296/25877305-2019-12-22

Yu. Evsyutina, Candidate of Medical Sciences; National Medical Research Center for Preventive Medicine, Ministry of Health of Russia, Moscow

The prevalence of non-alcoholic fatty liver disease (NAFLD) worldwide is 25%; this rate is much higher in the Russian Federation. NAFLD is closely associated with obesity, type 2 diabetes mellitus, metabolic syndrome, and cardiovascular diseases. Patients with NAFLD have a significantly increased risk for cirrhosis, terminal liver failure requiring liver transplantation, as well as hepatocellular carcinoma and mortality (overall, cardiovascular and liver-related). The prevention and treatment of NAFLD are aimed at correcting modifiable risk factors, primarily at losing weight (by 7–10% of the baseline value) through moderate physical activity per day and a low-calorie diet.

non-alcoholic fatty liver disease
non-alcoholic steatohepatitis
hepatocellular carcinoma
physical activity

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