PRECISION MEDICINE AND MOLECULAR THERANOSTICS

Download full text PDF
Issue: 
12
Year: 
2016

A. Melerzanov (1), Candidate of Medical Sciences; A. Moskalev (1), V. Zharov (2) 1 -Moscow Institute of Physics and Technology 2 -Center of Nanomedicine, University of Arkansas for Medical Sciences

Modern medical science is developing rapidly; new knowledge, approaches, and their new definitions are emerging. The term «precision medicine» has appeared relatively recently and combined the approaches of classical medicine with current approaches based on genetic and molecular diagnosis.

Keywords: 
precision medicine
molecular theranostics
personalized therapy



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Kim J., Galanzha E., Zaharoff D. et al. Nanotheranostics of circulating tumor cells, infections and other pathological features in vivo // Mol. Pha. – 2013; 10: 813–30.
  2. Zharov V. Revolutionising blood testing // Intern. Innovatn EU. – 2010; 97–9.
  3. Galanzha E., Zharov V. Circulating tumor cell detection and capturing using photoacoustic flow cytometry in vivo and ex vivo (review) // Cancers. – 2013; 5: 1691–738.
  4. Galanzha E., Shashkov E., Kim J.-W. et al. In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells // Nat. Nanotechnol. – 2009; 4: 855–60.
  5. Galanzha E., Viegas M., Malinsky T. et al. In vivo acoustic and photoacoustic focusing of circulating cells // Scientific Reports. – 2016; 16 (6): 21531. doi: 10.1038/srep21531.
  6. Menyaev Y., Carey K., Nedosekin D. et al. Preclinical photoacoustic models: application for ultrasensitive single cell malaria diagnosis in large vein and artery // Biomed. Opt. Express. – 2016; 7 (8): 3151–62. doi: 10.1364/BOE.7.003151
  7. Juratli M., Menyaev Y., Sarimollaoglu M. et al. Real-time embolus detection during surgery using in vivo photoacoustic flow cytometry // PLoS One. – 2016; 11: e0156269. doi: 0.1371/journal.pone.0156269
  8. Genetic predisposition vs Modifiers: https://cpmc.coriell.org
  9. Moskalev A.A. Konferentsii «Fiztehmed-3». Materialy prezentatsii «Geroprotektory». – FBMF MFTI, 2016.