GENOTOXICITY ANALYSIS IN MISCARRIAGE

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Issue: 
3
Year: 
2016

V. Goncharova (1); A. Zhanataev (2), Candidate of Biological Sciences; Z. Chaika (2); Professor A. Durnev (2), MD, Corresponding Member of the Russian Academy of Sciences; N. Bogdan (2); N. Lutsenko (1), Candidate of Medical Sciences; K. Morozova (1), Candidate of Medical Sciences; S. Lunina (1); Professor Yu. Dobrokhotova (1), MD; Professor O. Makarov (1), MD 1 -N.I. Pirogov Russian National Research Medical University, Moscow 2 -V.V. Zakusov Research Institute of Pharmacology, Moscow

The performed clinical trial has investigated venous blood genotoxicity indicators (DNA comet level, extracellular DNA, p53 protein level, and leukocyte susceptibility to a prooxidant) in miscarriage.
Keywords: 
obstetrics and gynecology
miscarriage
oxidative stress
DNA damage
p53 protein

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