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HEMOCORRECTION METHODS IN THE TREATMENT OF PSORIASIS

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Issue: 
8
Year: 
2015

V. Baityakov (1), MD; N. Filimonkova (2), MD; L. Novikova (1), Candidate of Medical Sciences 1 -N.P. Ogarev Mordovian State University, Saransk 2 -Ural Research Institute of Dermatovenereology and Immunopathology, Ministry of Health of Russia, Yekaterinburg

A total of 150 patients (mean age 37.5 years) with an exacerbation of generalized psoriasis vulgaris were examined to investigate the impact of plasmapheresis, ozone therapy, and their combination on its clinical course and some parameters of humoral immunity. A hyperactive humoral immune response with the high level of circulating immune complexes and the increased levels of IgM, IgA, and proinflammatory cytokines was found in the patients with psoriasis. Hemocorrection methods used in patients with psoriasis contributed to the enhanced clinical efficiency of treatment, better quality of life in the patients, and selective correction of impaired immunological parameters.

Keywords: 
psoriasis vulgaris
humoral immunity
cytokines
plasmapheresis
ozone therapy



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References: 
  1. Lepahin V.K., Astahova A.V., Ovchinnikova E.A. i dr. Vrachebnye oshibki kak prichina oslozhnenij lekarstvennoj terapii // Kachestvennaja klin. prak-tika. – 2002; 1: 71–7.
  2. Krueger J., Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis // Ann. Rheumat. Dis. – 2005; 64: 1130–6.
  3. Piksin I.N., Fedosejkin I.V., Bjakin S.P. Kvantovye i efferentnye metody lechenija v hirurgii / M.: Nauka, 2010; 248 s.
  4. Veksler N.Ju., Bojarinov G.A., Makarov N.A. i dr. Taktika intensivnoj terapii bol'nyh s ostrym destruktivnym pankreatitom // Vestnik intensiv-noj terapii. – 2004; 5: 180–3.
  5. Danilov A.Ju. Kliniko-patogeneticheskoe obosnovanie primenenija efferentnyh metodov i ozonoterapii v rannej reabilitatsii bol'nyh, perenesshih miomektomiju. Avtoref. dis. … d-ra med. nauk. M., 2009; 48 s.
  6. Maslennikov O.V., Kontorschikova K.N., Gribkova I.A. Rukovodstvo po ozonoterapii / N. Novgorod: Vektor-TiS, 2008; 326 s.
  7. Znamenskaja L.F., Egorova Ju.Ju., Zitner S.V. Mehanizm realizatsii bio logicheskogo dejstvija faktora nekroza opuholi pri psoriaze // Vestn. derma-tol. i venerol. – 2011; 2: 13–7.
  8. Belova O.V., Arion V.Ja., Sergienko V.I. Rol' tsitokinov v immunologicheskoj funktsii kozhi // Immunopatol., allergol., infektol. – 2008; 1: 41–55
  9. Bitkina O., Kosheleva I., Baityakov V. Ozone therapy using in dermatological practice. Russian experience // Revista Española de Ozonoterapia. – 2014; 4 (3): 62.
  10. Bocci V. Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today // J. Biolog. Regulators and Homeostatic agents. – 1997; 10 (2/3): 31–53.
  11. Furusawa K., Hasegawa T., Ikeda S. Immunosuppressant and infliximabresistant generalized pustular psoriasis successfully treated with granulocyte and monocyte adsorption apheresis // Ther. Apher. Dial. – 2012; 16 (4): 379–80.
  12. Liumbruno G., Centoni P., Molfettini P. et al. Lymphocytapheresis in the treatment of psoriasis vulgaris // J. Clin. Apher. – 2006; 21: 158–64.