Новая коронавирусная инфекция: селен, селенсодержащие препараты, профилактика осложнений

DOI: https://doi.org/10.29296/25877305-2022-04-13
Номер журнала: 
4
Год издания: 
2022

Д.В. Дедов, доктор медицинских наук, профессор
Тверской государственный медицинский университет
Тверской областной клинический кардиологический диспансер
E-mail: dedov_d@inbox.ru

В статье представлен обзор российских и зарубежных исследований, посвященных изучению значения селена и селенсодержащих препаратов в профилактике осложнений новой коронавирусной инфекции.
Ключевые слова: 
новая коронавирусная инфекция
профилактика
осложнение
селен
селеноцистин
SELENBIO for women
селеноцистеин
астрагал шерстистоцветковый
Для цитирования
Дедов Д.В. Новая коронавирусная инфекция: селен, селенсодержащие препараты, профилактика осложнений . Врач, 2022; (4): 85-88 https://doi.org/10.29296/25877305-2022-04-13

Список литературы: 
  1. Авдеев С.Н., Адамян Л.В., Алексеева Е.И. и др. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Временные методические рекомендации. М.: Минздрав России, 2021; 260 с.
  2. Calder P.C., Carr A.C., Gombart A.F. et al. Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients. 2020; 12 (4): 1181. DOI: 10.3390/nu12041181
  3. Stratton C.W., Tang Y.W., Lu H. Pathogenesis-directed therapy of 2019 novel coronavirus disease. J Med Virol. 2021; 93 (3): 1320–42. DOI: 10.1002/jmv.26610
  4. Barazzoni R., Bischoff S.C., Breda J. et al. Еndorsed by the ESPEN Council. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection. Clin Nutr. 2020; 39 (6): 1631–8. DOI: 10.1016/j.clnu.2020.03.022
  5. Berger M.M., Herter-Aeberli I., Zimmermann M.B. et al. Strengthening the immunity of the Swiss population with micronutrients: A narrative review and call for action. Clin Nutr ESPEN. 2021; 43: 39–48. DOI: 10.1016/j.clnesp.2021.03.012
  6. Fakhrolmobasheri M., Mazaheri-Tehrani S., Kieliszek M. et al. COVID-19 and Selenium Deficiency: a Systematic Review. Biol Trace Elem Res. 2021: 1–12. DOI: 10.1007/s12011-021-02997-4
  7. James P.T., Ali Z., Armitage A.E. et al. The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review. J Nutr. 2021; 151 (7): 1854–78. DOI: 10.1093/jn/nxab059
  8. Fairweather-Tait S.J., Bao Y., Broadley M.R. et al. Selenium in human health and disease. Antioxid Redox Signal. 2011; 14 (7): 1337–83. DOI: 10.1089/ars.2010.3275
  9. Prabhu K.S., Lei X.G. Selenium. Adv Nutr. 2016; 7 (2): 415–7. DOI: 10.3945/an.115.010785
  10. BourBour F., Mirzaei Dahka S., Gholamalizadeh M. et al. Nutrients in prevention, treatment, and management of viral infections; special focus on Coronavirus. Arch Physiol Biochem. 2020; 9: 1–10. DOI: 10.1080/13813455.2020.1791188
  11. Bae M., Kim H. Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19. Molecules. 2020; 25 (22): 5346. DOI: 10.3390/molecules25225346
  12. Galmés S., Serra F., Palou A. Current State of Evidence: Influence of Nutritional and Nutrigenetic Factors on Immunity in the COVID-19 Pandemic Framework. Nutrients. 2020; 12 (9): 2738. DOI: 10.3390/nu12092738
  13. Loffredo F., Giampieri E., Corazza I. et al. Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy. Aging Clin Exp Res. 2020; 32 (10): 2115–31. DOI: 10.1007/s40520-020-01669-y
  14. Alexander J., Tinkov A., Strand T.A. et al. Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19. Nutrients. 2020; 12 (8): 2358. DOI: 10.3390/nu12082358
  15. Liu Q., Zhao X., Ma J. et al. Selenium (Se) plays a key role in the biological effects of some viruses: Implications for COVID-19. Environ Res. 2021; 196: 110984. DOI: 10.1016/j.envres.2021.110984
  16. Majeed M., Nagabhushanam K., Gowda S. et al. An exploratory study of selenium status in healthy individuals and in patients with COVID-19 in a south Indian population: The case for adequate selenium status. Nutrition. 2021; 82: 111053. DOI: 10.1016/j.nut.2020.111053
  17. Younesian O., Khodabakhshi B., Abdolahi N. et al. Decreased Serum Selenium Levels of COVID-19 Patients in Comparison with Healthy Individuals. Biol Trace Elem Res. 2021: 1–6. DOI: 10.1007/s12011-021-02797-w
  18. Moghaddam A., Heller R.A., Sun Q. et al. Selenium Deficiency Is Associated with Mortality Risk from COVID-19. Nutrients. 2020; 12 (7): 2098. DOI: 10.3390/nu12072098
  19. Razeghi Jahromi S., Moradi Tabriz H., Togha M. et al. The correlation between serum selenium, zinc, and COVID-19 severity: an observational study. BMC Infect Dis. 2021; 21 (1): 899. DOI: 10.1186/s12879-021-06617-3
  20. Gorini F., Sabatino L., Pingitore A. et al. Selenium: An Element of Life Essential for Thyroid Function. Molecules. 2021; 26 (23): 7084. DOI: 10.3390/molecules26237084
  21. Zhang J., Saad R., Taylor E.W. et al. Selenium and selenoproteins in viral infection with potential relevance to COVID-19. Redox Biol. 2020; 37: 101715. DOI: 10.1016/j.redox.2020.101715
  22. Kieliszek M., Lipinski B. Selenium supplementation in the prevention of coronavirus infections (COVID-19). Med Hypotheses. 2020; 143: 109878. DOI: 10.1016/j.mehy.2020.109878
  23. Khatiwada S., Subedi A. A Mechanistic Link Between Selenium and Coronavirus Disease 2019 (COVID-19). Curr Nutr Rep. 2021; 10 (2): 125–36. DOI: 10.1007/s13668-021-00354-4
  24. Manzanares W., Moreira E., Hardy G. Pharmaconutrition revisited for critically ill patients with coronavirus disease 2019 (COVID-19): Does selenium have a place? Nutrition. 2021; 81: 110989. DOI: 10.1016/j.nut.2020.110989
  25. Wrobel J.K., Power R., Toborek M. Biological activity of selenium: Revisited. IUBMB Life. 2016; 68 (2): 97–105. DOI: 10.1002/iub.1466
  26. Полубояринов П.А., Елистратов Д.Г., Швец В.И. Метаболизм и механизм токсичности селенсодержащих препаратов, используемых для коррекции дефицита микроэлемента селена. Тонкие химические технологии. 2019; 14 (1): 5–24. DOI: 10.32362/2410-6593-2019-14-1-5-24
  27. Mangiapane E., Pessione A., Pessione E. Selenium and selenoproteins: an overview on different biological systems. Curr Protein Pept Sci. 2014; 15 (6): 598–607. DOI: 10.2174/1389203715666140608151134
  28. Hossain A., Skalicky M., Brestic M. et al. Selenium Biofortification: Roles, Mechanisms, Responses and Prospects. Molecules. 2021; 26 (4): 881. DOI: 10.3390/molecules26040881
  29. Zhang J., Taylor E.W., Bennett K. et al. Association between regional selenium status and reported outcome of COVID-19 cases in China. Am J Clin Nutr. 2020; 111 (6): 1297–9. DOI: 10.1093/ajcn/nqaa095
  30. Hargreaves I.R., Mantle D. COVID-19, Coenzyme Q10 and Selenium. Adv Exp Med Biol. 2021; 1327: 161–8. DOI: 10.1007/978-3-030-71697-4_13
  31. Shakoor H., Feehan J., Al Dhaheri A.S. et al. Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas. 2021; 143: 1–9. DOI: 10.1016/j.maturitas.2020.08.003
  32. Zhang H.Y., Zhang A.R., Lu Q.B. et al. Association between fatality rate of COVID-19 and selenium deficiency in China. BMC Infect Dis. 2021; 21 (1): 452. DOI: 10.1186/s12879-021-06167-8
  33. Bermano G., Méplan C., Mercer D.K. et al. Selenium and viral infection: are there lessons for COVID-19? Br J Nutr. 2021; 125 (6): 618–27. DOI: 10.1017/S0007114520003128
  34. Palakshappa J.A., Krall J.T.W., Belfield L.T. et al. Long-Term Outcomes in Acute Respiratory Distress Syndrome: Epidemiology, Mechanisms, and Patient Evaluation. Crit Care Clin. 2021; 37 (4): 895–911. DOI: 10.1016/j.ccc.2021.05.010
  35. Seyed Hosseini E., Riahi Kashani N., Nikzad H. et al. The novel coronavirus Disease-2019 (COVID-19): Mechanism of action, detection and recent therapeutic strategies. Virology. 2020; 551: 1–9. DOI: 10.1016/j.virol.2020.08.011
  36. Елистратов Д.Г. Остео-Вит D3 и СЕЛЕНБИО фо вумен в профилактике COVID-19 и постковидных осложнений. Медицинская сестра. 2022; 24 (2): 42–8. DOI: 10.29296/25879979-2022-02-10