Возможности применения биологически активной добавки SELENBIO for women при нарушениях репродуктивного здоровья
DOI: https://doi.org/10.29296/25877305-2022-01-04
Номер журнала:
1
Год издания:
2022
Проведен обзор сведений о влиянии микроэлемента селена (Se) на репродуктивное здоровье,
беременность и лактацию. Представлены данные исследований, показавшие, что повышенная потребность в Se
отмечается во время беременности и лактации, а дефицит данного микроэлемента приводит к нарушениям
репродуктивной системы, осложнениям беременности и родов, развитиям нарушений у плода. Показано, что
способом профилактики дефицита Se может быть применение биологически активной добавки SELENBIO for women,
содержащей селен, цинк, витамины С и Е.
Ключевые слова:
терапия
репродуктивное здоровье
беременность
лактация
селен
SELENBIO for women
селеноцистеин
селеноцистин
Для цитирования
Т.В. Потупчик, Е.В. Окладникова, О.Ф. Веселова, Т.В. Дресвянская Возможности применения биологически активной добавки SELENBIO for women при нарушениях репродуктивного
здоровья
. Врач, 2022; (1): 25-31 https://doi.org/10.29296/25877305-2022-01-04Список литературы:
- Борисов В.В. Микроэлементы селен и цинк в организме женщины и мужчины: проблемы и решения. Consilium Medicum. 2018; 20 (7): 63–8 [Borisov V.V. Microelements selenium and zinc in female and male body: problems and solutions. Consilium Medicum. 2018; 20 (7): 63–8 (in Russ.)]. DOI: 10.26442/2075-1753_2018.7.63-68
- Голубкина Н.А. Селен в медицине и экологии. М.: КМК, 2002 [Golubkina N.A. Selenium in medicine and ecology. Moscow: KMK, 2002 (in Russ.)].
- Дедов Д.В. Cелен и селенсодержащие препараты: значение для организма и профилактики различных заболеваний. Фармация. 2021; 70 (8): 54–7 [Dedov D.V. Selenium and selenium-containing drugs: importance for the body and prevention of various diseases. Pharmacy. 2021; 70 (8): 54–7 (in Russ.)]. DOI: 10.29296/25419218-2021-08-09
- Ключников С.О., Дещекина М.Ф., Демин В.Ф. Минеральный состав сыворотки крови новорожденных в раннем неонатальном периоде. Педиатрия. 1995; 3: 28–32 [Klyuchnikov S.O., Deshchekina M.F., Demin V.F. Mineral composition of blood serum of newborns in the early neonatal period. Pediatrics. 1995; 3: 28–32 (in Russ.)].
- Ключников С.О., Дещекина М.Ф., Демин В.Ф. Содержание макро- и микроэлементов в сыворотке крови новорожденных как один из критериев оценки состояния при рождении. Педиатрия. 1994; 6: 53–5 [Klyuchnikov S.O., Deshchekina M.F., Demin V.F. The content of macro- and microelements in the blood serum of newborns as one of the criteria for assessing the condition at birth. Pediatrics. 1994; 6: 53–5 (in Russ.)].
- Полубояринов П.А. Исследование биофортификации растений астрагала Астрагала шерстистоцветкового (Astragalus dasyanthus Pall.) аминокислотой L-селеноцистеином. Вопросы биологической, медицинской и фармацевтической химии. 2019; 22 (12): 64 [Poluboyarinov P.A. Biofortification of Astragalus astragalus woolly-flowered (Astragalus dasyanthus Pall.) plants with the amino acid L-selenocysteine. Problems of biological, medical and pharmaceutical chemistry. 2019; 22 (12): 64 (in Russ.)]. URL: https://www.secret-dolgolet.ru/biofortifikatsiya-rasteniy-astragala-sherstistotsvetkovogo-astragalus-dasyanthus-pall-aminokislotoy-l-selenotsistinom/
- Полубояринов П.А., Елистратов Д.Г., Швец В.И. Метаболизм и механизм токсичности селенсодержащих препаратов, используемых для коррекции дефицита микроэлемента селена. Тонкие химические технологии. 2019; 14 (1): 5–24 [Poluboyarinov P.A., Elistratov D.G., Shvets V.I. Metabolism and mechanism of toxicity of selenium-containing supplements used for optimizing human selenium status. Fine Chemical Technologies. 2019; 14 (1): 5–24 (in Russ.)]. DOI: 10.32362/2410-6593-2019-14-1-5-24
- Сенькевич О.А. Комарова З.А. Дефицит селена в преконцепции и лактации: последствия и пути коррекции. Дальневосточный медицинский журнал. 2016; 2: 42–6 [Senkevich O.A. Komarova Z.A. Selenium deficiency in preception and lactation: consequences and ways of correction. Far Eastern Medical Journal. 2016; 2: 42–6 (in Russ.)].
- Тутельян В.А., Княжев В.А., Хотимченко С.А. и др. Селен в организме человека: метаболизм, антиоксидантные свойства, роль в канцерогенезе. М.: РАМН, 2002 [Tutelyan V.A., Knyazhev V.A., Khotimchenko S.A. et al. Selenium in the human body: metabolism, antioxidant properties, role in carcinogenesis. M.: RAMS, 2002 (in Russ.)].
- Тутельян В.А., Мазо В.К., Ширина Л.И. Значение селена в полноценном питании человека. Гинекология. 2002; 4 (2): 88–90 [Tutelyan V.A., Mazo V.K., Shirota L.I. The importance of selenium in a person’s full nutrition. Gynecology. 2002; 4 (2): 88–90 (in Russ.)].
- Шилин Д.Е., Спиричев В.Б. Минеральный гомеостаз и костный метаболизм в организме беременной, плода, ребенка. Остеопороз и остеопатии. 2006; 6: 26–31 [Shilin D.E., Spirichev V.B. Mineral homeostasis and bone metabolism in the body of a pregnant woman, fetus, child. Osteoporosis and osteopathies. 2006; 6: 26–31. (in Russ.)].
- Alexander J., Tinkov A., Strand T.A. et al. Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19. Aaseth J.Nutrients. 2020; 12 (8): 2358. DOI: 10.3390/nu12082358
- Al-Sheikh Y.A., Al-Zahrani K.Y. The Status of Biochemical and Molecular Markers of Oxidative Stress in Preeclamptic Saudi Patients. Curr Mol Med. 2018; 18 (7): 475–85. DOI: 10.2174/1566524019666190104105843
- Barrington J.W., Linsay P., James D. et al. Selenium deficiency and miscarriage: a possible link? Br J Obstet Gynaecol. 1996; 103 (2): 130–2. DOI: 10.1111/j.1471-0528
- Beno I., Ondreicka R., Magalova T. et al. Precancerous conditions and carcinomas of the stomach and colorectum-blood levels of selected micronutrients. Bratisl Lek Listy. 1997; 98 (12): 674–7.
- Bouvier N., Millart H. Relationships between selenium deficiency and 3,5,3’-triiodothyronine (T3) synthesis. Ann Endocrinol (Paris). 1997; 58 (4): 310–5.
- Daniels L., Gibson R.A., Simmer K. et al. Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial. Am J Clin Nutr. 2008; 88 (1): 70–6. DOI: 10.1093/ajcn/88.1.70
- Dodge M.L., Wander. RC., Xia Y. et al. Glutathione peroxidase activity modulates fatty acid profiles of plasma and breast milk in Chinese women. J Trace Elem Med Biol. 1999; 12 (4): 221–30. DOI: 10.1016/S0946-672X(99)80062-5
- Dorea J.G. Selenium and breast-feeding. Br J Nutr. 2002;88 (5): 443–61. DOI: 10.1079/BJN2002692
- Duntas L.H. Selenium and at-risk pregnancy: challenges and controversies. Thyroid Res. 2020; 13: 16. DOI: 10.1186/s13044-020-00090-x
- Flohe L. Selenium in peroxide metabolism. Med Klin. 1997; 92 (3): 5–7. DOI: 10.1007/BF03041948
- Gać P., Czerwińska K., Macek P. et al. The importance of selenium and zinc deficiency in cardiovascular disorders. Environ Toxicol Pharmacol. 2021; 82: 103553. DOI: 10.1016/j.etap.2020.103553
- Heidar Z., Hamzepour N., Modarres S.Z. et al. The Effects of Selenium Supplementation on Clinical Symptoms and Gene Expression Related to Inflammation and Vascular Endothelial Growth Factor in Infertile Women Candidate for In Vitro Fertilization. Biol Trace Elem Res. 2020; 193 (2): 319–25. DOI: 10.1007/s12011-019-01715-5.
- Hung T.H., Lo L.M., Chiu T.H. et al. A longitudinal study of oxidative stress and antioxidant status in women with uncomplicated pregnancies throughout Gestation. Reprod Sci. 2010; 17 (4): 401–9. DOI: 10.1177/1933719109359704
- Huang X., Dong Y.L., Li T. et al. Dietary Selenium Regulates microRNAs in Metabolic Disease: Recent Progress. Nutrients. 2021; 13 (5): 1527. DOI: 10.3390/nu13051527
- Kvicala J., Zamrazil V., Soutorova M. et al. Correlations between parameters of body selenium status and peripheral thyroid parameters in the low selenium region. Analyst. 1995; 120 (3): 959–65. DOI: 10.1039/an9952000959
- Lee A.S.E., Ji Y., Raghavan R. et al. Maternal prenatal selenium levels and child risk of neurodevelopmental disorders: A prospective birth cohort study. Autism Res. 2021; 14 (12): 2533–43. DOI: 10.1002/aur.2617
- Lewandowska M., Sajdak S., Lubiński J. Serum selenium level in early healthy pregnancy as a risk marker of pregnancy induced hypertension. Nutrients. 2019; 11 (5): 1028. DOI: 10.3390/nu1105102
- Lorenzetti S., Plösch T., Teller I.C. Antioxidative molecules in human milk and environmental contaminants. Antioxidants. 2021; 10: 550. DOI: 10.3390/antiox10040550
- Mantovani G., Isidori A.M., Moretti C. et al. Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the «SERENA study», a randomized, double-blind, placebo-controlled trial. Endocrine. 2019; 66 (3): 542–50. DOI: 10.1007/s12020-019-01958-1
- Mehdi Y., Hornick J.L., Istasse L. et al. Selenium in the environment, metabolism and involvement in body functions. Molecules. 2013; 18: 3292–311. DOI: 10.3390/molecules18033292
- Mihailovic M., Cvetkovic M., Ljubic A. et al. Selenium and malonidialdehyde content and glutathione peroxidase activity in maternal and umbilical cord blood and amniotic fluid. Biol Trace Elem Res. 2000; 73 (1): 47–54. DOI: 10.1385/BTER:73:1:47
- Mirnamniha M., Faroughi F., Tahmasbpour E. et al. An overview on role of some trace elements in human reproductive health, sperm function and fertilization process. Rev Environ Health. 2019; 34 (4): 339–48. DOI: 10.1515/reveh-2019-0008
- Mistry H.D., Pipkin F.B., Redman C.W.G. et al. Selenium in reproductive health. Am J Obstet Gynecol. 2012; 206 (1): 21–30. DOI: 10.1016/j.ajog.2011.07.034
- Mojadadi A., Au A., Salah W. et al. Role for Selenium in Metabolic Homeostasis and Human Reproduction. Nutrients. 2021; 13 (9): 3256. DOI: 10.3390/nu13093256
- Mostafa-Gharehbaghi M., Mostafa-Gharabaghi P., Ghanbari F. et al. Determination of selenium in serum samples of preterm newborn infants with bronchopulmonary dysplasia using a validated hydride generation system. Biol Trace Elem Res. 2012; 147 (1–3): 1–7. DOI: 10.1007/s12011-011-9270-z
- Na J.Y., Seok J., Park S. et al. Effects of selenium on the survival and invasion of trophoblasts. Clin Exp Reprod Med. 2018; 45 (1): 10–6. DOI: 10.5653/cerm.2018.45.1.10
- Nikniaz L., Mahavi R., Ostadrahimi A. et al. Synbiotic supplementation is not effective on breast milk selenium concentrations and growth of exclusively breast fed infants: a pilot study. Int J Vitam Nutr Res. 2019; 89 (1–2): 73–9. DOI: 10.1024/0300-9831/a000549
- Oropeza-Moe M., Wisløff H., Bernhoft A. Selenium deficiency associated porcine and human cardiomyopathies. J Trace Elem Med Biol. 2015; 31: 148–56. DOI: 10.1016/j.jtemb.2014.09.011
- Pi X., Wei Y., Li Z. et al. Higher concentration of selenium in placental tissues is associated with reduced risk for orofacial clefts. Clin Nutr. 2019; 38 (5): 2442–8. DOI: 10.1016/j.clnu.2018.11.002
- Pieczynska J., Grajeta H. The role of selenium in human conception and pregnancy. J Trace Elem Med Biol. 2015; 29 (1): 31–8. DOI: 10.1016/j.jtemb.2014.07.003
- Qazi I.H., Angel C., Yang H. et al. Selenium, Selenoproteins, and Female Reproduction: A Review. Molecules. 2018; 23 (12): 3053. DOI: 10.3390/molecules23123053
- Rashidi B.H., Hosseinzadeh F.M., Alipoor E. et al. Effects of Selenium Supplementation on Asymmetric Dimethylarginine and Cardiometabolic Risk Factors in Patients with Polycystic Ovary Syndrome. Biol Trace Elem Res. 2020; 196 (2): 430–7. DOI: 10.1007/s12011-019-01954-6
- Rayman M.P. Selenium and human health. Lancet. 2012; 379 (9822): 1256–68. DOI: 10.1016/S0140-6736(11)61452-9
- Rayman M.P., Bath S.C., Westaway J. et al. Selenium status in U.K. pregnant women and its relationship with hypertensive conditions of pregnancy. Br J Nutr. 2015; 113 (2): 249–58. DOI: 10.1017/S000711451400364X
- Rayman M.P., Searle E., Kelly L. et al. Effect of selenium on markers of risk of preeclampsia in UK pregnant women: a randomised, controlled pilot trial. Br J Nutr. 2014; 112 (1): 99–111. DOI: 10.1017/S0007114514000531
- Schomburg L., Orho-Melander M., Struck J. et al. Selenoprotein-P Deficiency Predicts Cardiovascular Disease and Death. Nutrients. 2019; 11 (8): 1852. DOI: 10.3390/nu11081852
- Shahidi F., De Camargo A.C. Tocopherols and tocotrienols in common and emerging dietary sources: Occurrence, applications, and health benefits. Int J Mol Sci. 2016; 17 (10): 1745. DOI: 10.3390/ijms17101745
- Shimada B.K., Alfulaij N., Seale L.A. The Impact of Selenium Deficiency on Cardiovascular Function. Int J Mol Sci. 2021; 22 (19): 10713. DOI: 10.3390/ijms221910713
- Skröder H.M., Hamadani J.D., Tofail F. et al. Selenium status in pregnancy influences children’s cognitive function at 1.5 years of age. Clin Nutr. 2015; 34 (5): 923–30. DOI: 10.1016/j.clnu.2014.09.020
- Song M., Kumaran M.N., Gounder M. et al. Phase I trial of selenium plus chemotherapy in gynecologic cancers. Gynecol Oncol. 2018; 150 (3): 478–86. DOI: 51.1016/j.ygyno.2018.07.001
- Tara F., Maamouri G., Rayman M.P. et al. Selenium supplementation and the incidence of preeclampsia in pregnant Iranian women: a randomized, double-blind, placebo-controlled pilot trial. Taiwan J Obstet Gynecol. 2010; 49 (2): 181–7. DOI: 10.1016/S1028-4559(10)60038-1
- Tara F., Rayman M.P., Boskabadi H. et al. Selenium supplementation and premature (pre-labour) rupture of membranes: a randomised double-blind placebo-controlled trial. J Obstet Gynaecol. 2010; 30 (1): 30–4. DOI: 10.3109/01443610903267507
- Veisa V., Kalere I., Zake T. et al. Assessment of Iodine and Selenium Nutritional Status in Women of Reproductive Age in Latvia. Medicina (Kaunas). 2021; 57 (11): 1211. DOI: 10.3390/medicina57111211
- Wąsowicz W., Wolkanin P., Bednarski M. et al. Plasma trace element (Se, Zn, Cu) concentration in maternal and umbilical cord blood in Poland. Biol Trace Elem Res. 1993; 38 (2): 205–15. DOI: 10.1007/BF02784053
- Xu M., Guo D., Gu H. et al. Selenium and Preeclampsia: a Systematic Review and Meta-analysis. Biol Trace Elem Res. 2016; 171 (2): 283–92. DOI: 10.1007/s12011-015-0545-7
- Zheng G.X., Lin J.T., Zheng W.H. et al. Energy intake, oxidative stress and antioxidant in mice during lactation. Dongwuxue Yanjiu. 2015;36: 95–102. DOI: 10.13918/j.issn.2095-8137.2015.2.95