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Impact of intravenous laser blood irradiation on the time course of changes in some cytokine profile indicators and cortisol and melatonin levels in patients with rheumatoid arthritis

DOI: https://doi.org/10.29296/25877305-2022-10-17

Z. Tsagaraeva, Candidate of Medical Sciences; N. Burduli, Candidate of Medical Sciences; Professor N. Burduli, MD; Z. Brtsieva, Candidate of Medical Sciences; M. Brtsieva; D. Bestaev, MD
North Ossetian State Medical Academy, Ministry of Health of Russia, Vladikavkaz

Rheumatoid arthritis (RA) lowers quality of life and contributes to early disability in able-bodied patients. Non-drug therapy for RA, which includes intravenous laser blood irradiation, is an additional procedure that can improve the patient’s health and functional status. Objective. To study the time course of changes in some cytokine profile indicators and melatonin and cortisol levels in patients with RA when intravenous laser blood irradiation is incorporated into the therapy. Subjects and methods. A total of 112 patients with RA were examined. The diagnosis was established according to the ACR/EULAR criteria. The patients were divided into 2 groups: a study group of patients who received an intravenous laser therapy cycle in addition to intravenous laser therapy and a control group of those who had traditional drug therapy only. The cycle of intravenous laser therapy was performed using a Matrix-ILBI device (Matrix, Russia) and consisted of 10 sessions. Conclusion. The findings may state that combination therapy using intravenous laser blood irradiation is accompanied by the elimination of an imbalance ratio of pro-inflammatory to anti-inflammatory cytokines and also causes a decrease in melatonin levels and an increase in cortisol ones.

rheumatoid arthritis
intravenous laser blood irradiation

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