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Restoration of female sexual function in the rehabilitation program after surgical treatment for endometrial cancer

DOI: https://doi.org/10.29296/25877305-2022-10-12

L. Sandzhieva(1), D. Blinov, Candidate of Medical Sciences(2–4), Professor
A. Solopova(1), MD, Professor E. Achkasov(1), MD; Professor V. Galkin(5), MD;
D. Korabelnikov(4), Candidate of Medical Sciences; D. Petrenko1
1-I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
2-Institute of Preventive and Social Medicine, Moscow
3-Lapino Clinical Hospital, Village of Lapino, Moscow Region
4-F.P. Gaaz Moscow Sociomedical Institute, Moscow
5-City Clinical Oncology Hospital One, Moscow Healthcare Department

Objective. To evaluate the effectiveness of the developed comprehensive personalized rehabilitation program in restoring sexual function in female patients after radical treatment for endometrial cancer (EC). Subjects and methods. The investigation involved 61 reproductive-aged patients with histologically verified endometrioid carcinoma after radical surgery. The women were randomized into 2 groups: 1) 29 patients treated with an active rehabilitation through a comprehensive restorative program; 2) 32 patients treated with a passive rehabilitation, whose management corresponded to clinical recommendations. Follow-ups were performed at 1 week and 3, 6, and 12 months after surgery. Each visit included clinical examination and assessment of sexual function, by using the FSFI questionnaire. Results. Statistically significant differences between the groups were obtained after 6 and 12 months. At the end of the study, the total FSFI score showed an almost complete recovery of sexual function in the active rehabilitation group (a total FSFI score of 24.93±2.86), unlike the comparison group (a total FSFI score of 13.39±2.55; p < 0.001). Conclusion. Comprehensive personalized rehabilitation mitigates the consequences of radical surgery in patients with EC, contributing to the restoration of sexual function within 1 year after surgery.

endometrial cancer
sexual dysfunction
quality of life

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