VITAMIN U (S-METHYLMETHIONINE): METABOLIC EFFECTS AND CLINICAL EFFICACY

DOI: https://doi.org/10.29296/25877305-2022-10-10
Issue: 
10
Year: 
2022

A. Astapovskiy; O. Zhukova, Сandidate of Medical Sciences; Professor V. Drozdov, MD; Professor E. Shikh, MD
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Aim: to provide a brief overview of the metabolic effects of vitamin U, as well as current clinical studies on its effectiveness in various pathological conditions. Key points. S-methylmethionine, better known as vitamin U, is a metabolic substrate that affects many metabolic processes in the human body. It was first discovered in the 50s of the last centuries in cabbage juice. Since then, a large number of pre-clinical and clinical studies have been produced that have demonstrated the safety and effectiveness of vitamin U in various diseases. gastroprotective, hypolipidemic, antioxidant and organoprotective properties of vitamin U. In this review, more attention is paid to the gastroprotective properties of S-methylmethionine. Nevertheless, data are presented demonstrating its hypolipidemic, antioxidant and organoprotective properties, which allow the possibility of expanding the scope of its application in the future. Conclusion. The accumulated data on the effectiveness of vitamin U allow us to consider it as an adjunct to the main therapy of gastritis and ulcers in order to increase efficiency, as well as a means to prevent exacerbations.
Keywords: 
gastroenterology
vitamin U
S-methylmethionine
gastroprotection
gastritis
antioxidant

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