Gut dysbiosis: state-of-the-art

DOI: https://doi.org/10.29296/25877305-2022-10-06
Issue: 
10
Year: 
2022

Professor V. Skvortsov(1), MD; A. Sabanov(1), MD; Professor B. Levitan(2), MD; Candidate of Medical Sciences; G. Malyakin(1), R. Tinaeva(1),
1-Volgograd State Medical University, Ministry of Health of Russia
2-Astrakhan State Medical University, Ministry of Health of Russia

Maintaining the balanced gut microbial community is critical to maintaining gut health and preventing chronic inflammation. It is important that the impact of the microbiota on gut function and health depends on its constituent microbes. Dysbiosis (dysbacteriosis) means any changes in the composition of resident commensal communities compared to those found in healthy individuals. Microbial dysbiosis is characterized by a decrease in beneficial microbes, overgrowth of harmful microbes, and loss of microbial diversity. It is important to emphasize that dysbiosis is not a well-defined condition; the dysbiosis indices vary in methodology and clinical context and have been designed for different groups of people to describe many different conditions.
Keywords: 
dysbiosis
irritable bowel syndrome
gastrointestinal tract
intestinal microflora
bacteria
probiotics
prebiotics

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