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COVID-19: pathogenetic aspects

DOI: https://doi.org/10.29296/25877305-2022-10-01

Professor M. Akhmedova(1), MD; Professor O. Burgasova(2), MD; I. Imamova(1), Candidate of Medical Sciences; M. Maksudova(1), Candidate of Medical Sciences
1-Tashkent Medical Academy, Tashkent, Uzbekistan
2-Peoples’ Friendship University of Russia, Moscow

Understanding the pathogenetic aspects of COVID-19, which affect the development of the disease and its complications, will be able to improve the medical care provided. The paper considers a relationship between the trigger of release of pro-inflammatory cytokines and the development of infiltration in endothelial cells and between microvascular dysfunction and an increase in respiratory failure. Based on the data available in the literature, the authors describe the trigger of respiratory tract diseases and multiple organ failure, which contribute to COVID-19 progression

infectious diseases

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