Osteoporosis in postmenopausal women: sociomedical significance, prevention of fractures with Osteomed and Osteomed Forte
DOI: https://doi.org/10.29296/25877305-2022-01-11
Issue:
1
Year:
2022
The paper presents data from Russian and foreign studies on the sociomedical significance of
osteoporosis (OP) as a systemic disease of the skeleton. Women over 50 years of age in Russia are shown to
have OP and osteopenia in 34 and 43%, respectively. The pathogenesis of OP is depicted in women in
postmenopause. At this time the risk of osteoporotic fractures at different sites is noted to increase. The
paper considers various strategies for complex prevention and treatment of OP, including those with Osteomed
and Osteomed Forte.
Keywords:
women
osteoporosis
fractures
prevention
treatment
Osteomed
Osteomed Forte
References:
- Mel'nichenko G.A., Belaja Zh.E., Rozhinskaja L.Ja. i dr. Federal'nye klinicheskie rekomendatsii po diagnostike, lecheniju i profilaktike osteoporoza. Problemy endokrinologii. 2017; 63 (6): 392–426 [Melnichenko G.A., Belaia Zh.E., Rozhinskaia L.Ia. et al. Russian federal clinical guidelines on the diagnostics, treatment, and prevention of osteoporosis. Problemy Endokrinologii. 2017; 63 (6): 392–426 (in Russ.)]. DOI: 10.14341/probl2017636392-426
- Bojtsov S.A., Drapkina O.M., Shljahto E.V. i dr. Issledovanie ESSE-RF (Epidemiologija serdechno-sosudistyh zabolevanij i ih faktorov riska v regionah Rossijskoj Federatsii). Desjat' let spustja. Kardiovaskuljarnaja terapija i profilaktika. 2021; 20 (5): 3007 [Boytsov S.A., Drapkina O.M., Shlyakhto E.V. et al. Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Ten years later. Cardiovascular Therapy and Prevention. 2021; 20 (5): 3007 (in Russ.)]. DOI: 10.15829/1728-8800-2021-3007
- Shishkova V.N., Kosmatova O.V., Skripnikova I.A. i dr. Aktual'nye voprosy diagnostiki i terapii osteoporoza v praktike terapevta. Lechebnoe delo. 2021; 1: 52–61 [Shishkova V.N., Kosmatova O.V., Skripnikova I.A. et al. Topical issues of diagnosis and treatment of osteoporosis in the practice of general practitioner. Lechebnoe delo. 2021; 1: 52–61 (in Russ.)]. DOI: 10.24412/2071-5315-2021-12284
- Trifonov V., Elistratov D. Rekomendatsii po lecheniju osteoporoza v uslovijah komorbidnosti i polipragmazii s pomosch'ju preparata «Osteomed Forte» i fitopreparatov. Vrach. 2018; 29 (5): 87–8 [Trifonov V., Elistratov D. Recommendations for the treatment of osteoporosis with the drug «Osteomed Forte» and phytopreparations. Vrach. 2018; 29 (5): 87–8 (in Russ.)].
- Ismailova O., Eremina N., Strukov V. i dr. Kliniko-patogeneticheskie osobennosti hronicheskogo generalizovannogo parodontita u zhenschin v menopauze i ego morfometricheskie projavlenija na fone kompleksnoj terapii s primeneniem preparata Osteomed Forte. Vrach. 2019; 30 (10): 40–3 [Ismailova O., Eremina N., Strukov V. et al. Clinical and pathogenetic features of chronic generalized periodontitis in menopausal women and its morphometric manifestations during combination therapy using Osteomed Forte. Vrach. 2019; 30 (10): 40–43 (in Russ.)]. DOI: 10.29296/25877305-2019-10-08.
- Yong E.L., Logan S. Menopausal osteoporosis: screening, prevention and treatment. Singapore Med J. 2021; 62 (4): 159–66. DOI: 10.11622/smedj.2021036
- Bulgakova S.V., Treneva E.V., Zaharova N.O. i dr. Profilaktika osteoporoticheskih perelomov u lits pozhilogo i starcheskogo vozrasta. Vrach. 2020; 31 (9): 22–7 [Bulgakova S., Treneva E., Zakharova N. et al. Prevention of osteoporotic fractures in the elderly. Vrach. 2020; 31 (9): 22–27 (in Russ.)]. DOI: 10.29296/25877305-2020-09-04
- Lin S.Y., Hung M.C., Chang S.F. et al. Efficacy and Safety of Postmenopausal Osteoporosis Treatments: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Clin Med. 2021; 10 (14): 3043. DOI: 10.3390/jcm10143043
- Tan X., Wen F., Yang W. et al. Comparative efficacy and safety of pharmacological interventions for osteoporosis in postmenopausal women: a network meta-analysis (Chongqing, China). Menopause. 2019; 26 (8): 929–39. DOI: 10.1097/GME.0000000000001321
- Anagnostis P., Gkekas N.K., Potoupnis M. et al. New therapeutic targets for osteoporosis. Maturitas. 2019; 120: 1–6. DOI: 10.1016/j.maturitas.2018.11.010
- Perl'mutter O.A., Jarikov A.V., Lobanov I.A. i dr. Osteoporoz: tekuschee sostojanie problemy, sovremennye metody nejrovizualizatsii i printsipy lechenija. Vrach. 2020; 31 (12): 52–60 [Perlmutter O., Yarikov A., Lobanov I. et al. Osteoporosis: the current state of the problem, modern neuroimaging techniques, and treatment principles. Vrach. 2020; 31 (12): 52–60 (in Russ.)]. DOI: 10.29296/25877305-2020-12-11
- John Cecily H.S. Early Detection and Prevention of Osteoporosis Among Pre- and Postmenopausal Women in Saudi Arabia. Clin Nurs Res. 2020; 29 (1): 48–55. DOI: 10.1177/1054773818769209
- Leder B.Z., Clarke B.L., Shane E. et al. A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report «Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention». J Bone Miner Res. 2019; 34 (9): 1549–51. DOI: 10.1002/jbmr.3823
- Boudin E., Van Hul W. Genetics of human bone formation. 2017. Eur J Endocrinol. 2017; 177 (2): R69–R83. DOI: 10.1530/EJE-16-0990
- Compston J.E., McClung M.R., Leslie W.D. Osteoporosis. Lancet. 2019; 393 (10169): 364–76. DOI: 10.1016/S0140-6736(18)32112-3
- Yang L., Kang N., Yang J.C. et al. Drug efficacies on bone mineral density and fracture rate for the treatment of postmenopausal osteoporosis: a network meta-analysis. Eur Rev Med Pharmacol Sci. 2019; 23 (6): 2640–68. DOI: 10.26355/eurrev_201903_17414
- Wen F., Du H., Ding L. et. al. Clinical efficacy and safety of drug interventions for primary and secondary prevention of osteoporotic fractures in postmenopausal women: Network meta-analysis followed by factor and cluster analysis. PLoS One. 2020; 15 (6): e0234123. DOI: 10.1371/journal.pone.0234123
- Ding L.L., Wen F., Wang H. et al. Osteoporosis drugs for prevention of clinical fracture in white postmenopausal women: a network meta-analysis of survival data. Osteoporos Int. 2020; 31 (5): 961–71. DOI: 10.1007/s00198-019-05183-4
- Hernandez A.V., Pérez-López F.R., Piscoya A. et al. Comparative efficacy of bone anabolic therapies in women with postmenopausal osteoporosis: A systematic review and network meta-analysis of randomized controlled trials. Maturitas. 2019; 129: 12–22. DOI: 10.1016/j.maturitas.2019.08.003
- Jin Y.Z., Lee J.H., Xu B. et al. Effect of medications on prevention of secondary osteoporotic vertebral compression fracture, non-vertebral fracture, and discontinuation due to adverse events: a meta-analysis of randomized controlled trials. BMC Musculoskelet Disord. 2019; 20 (1): 399. DOI: 10.1186/s12891-019-2769-8
- Jurova O., Marchenkova L. Opyt primenenija BAD Osteomed Forte v kompleksnoj programme reabilitatsii patsientov s perelomom distal'nogo otdela predplech'ja na fone sistemnogo osteoporoza. Vrach. 2020; 31 (2): 47–52 [Yurova O., Marchenkova L. The experience of using of comprehensive rehabilitation program with dietary supplements Osteomed Forte in patients with a jsteoporotic distal forearm fracture. Vrach. 2020; 31 (2): 47–52 (in Russ.)]. DOI: 10.29296/25877305-2020-02-11
- Jarmolovich R.A., Salaev A.V. Uluchshenie regeneratornogo sposobnosti kostnoj tkani pri diafizarnyh perelomah trubchatyh kostej na fone primenenija Osteomed Forte. Vrach. 2020; 31 (5): 63–6 [Yarmolovich R., Salaev A. Osteomed Forte used to improve the regenerative capacity of bone tissue in diaphyseal tubular bone fractures. Vrach. 2020; 31 (5): 63–6 (in Russ.)]. DOI: 10.29296/25877305-2020-05-14
- Romanov D.V., Polikarpochkin A.N., Polikarpochkina E.V. Osteomed Forte v lechenii patsientov s travmami golenostopnogo sustava. Vrach. 2020; 31 (8): 70–4 [Romanov D., Polikarpochkin A., Polikarpochkina E. Osteomed Forte in the treatment of patients with ankle injuries. Vrach. 2020; 31 (8): 70–4 (in Russ.)]. DOI: 10.29296/25877305-2020-08-11
- Pavlova T., Bashuk I. Kliniko-morfologicheskie osobennosti degenerativnyh izmenenij kostnoj tkani na fone osteoporoza v vozrastnom aspekte. Vrach. 2019; 30 (6): 47–50 [Pavlova T., Bashuk I. Clinical and morphological features of degenerative changes in bone tissue with osteoporosis in age aspects. Vrach. 2019; 30 (6): 47–50 (in Russ.)]. DOI: 10.29296/25877305-2019-06-11
- Volotskaja N.I., Sulima A.N., Rumjantseva Z.S. Menopauza: sovremennye standarty diagnostiki i korrektsii narushenij. Vrach. 2021; 32 (3): 66–72 [Volotskaya N., Sulima A., Rumyantseva Z. Menopause: modern standards of diagnosis and correction of disorders. Vrach. 2021; 32 (3): 66–72 (in Russ.)]. DOI: 10.29296/25877305-2021-03-12
- Stepan J.J., Hruskova H., Kverka M. Update on Menopausal Hormone Therapy for Fracture Prevention. Curr Osteoporos Rep. 2019; 17 (6): 465–73. DOI: 10.1007/s11914-019-00549-3
- Strukov V., Elistratov D., Kislov A. i dr. Osteoporoz v geriatricheskoj praktike. Vrach. 2018; 29 (6): 26–30 [Strukov V., Elistratov D., Kislov A. et al. Osteoporosis in geriatric practice. Vrach. 2018; 29 (6): 26–30 (in Russ.)]. https://doi.org/10.29296/25877305-2018-06-05
- Jarikov A.V., Smirnov I.I., Pavlinov S.E. i dr. Osteoporoz pozvonochnika: epidemiologija, sovremennye metody diagnostiki i printsipy lechenija. Vrach. 2020; 31 (11): 21–8 [Yarikov A., Smirnov I., Pavlinov S. et al. Osteoporosis of the vertebral column: epidemiology, current diagnostic methods, and treatment principles. Vrach. 2020; 31 (11): 21–8 (in Russ.)]. DOI: 10.29296/25877305-2020-11-04
- Esedova A., Idrisova M. Korrektsija kostno-metabolicheskih narushenij v postmenopauze na fone tireoidnoj patologii. Vrach. 2017; 9: 41–6 [Esedova A., Idrisova M. Postmenopausal correction of bone metabolic disorders in the presence of thyroid diseases. Vrach. 2017; 9: 41–6 (in Russ.)].
- Migliorini F., Maffulli N., Colarossi G. et al. Effect of drugs on bone mineral density in postmenopausal osteoporosis: a Bayesian network meta-analysis. J Orthop Surg Res. 2021; 16 (1): 533. DOI: 10.1186/s13018-021-02678-x
- Prohorov M., Kislov A., Elistratov D. i dr. Vlijanie Osteomeda na konsolidatsiju perelomov kostej. Vrach. 2016; 2: 68–9 [Prokhorov M., Kislov A., Elistratov D. et al. Effect of Osteomed on consolidation of bone fractures. Vrach. 2016; 2: 68–9 (in Russ.)].
- Strukov V., Elistratov D., Balykova L. i dr. Vlijanie Osteomed Forte na gormonal'nyj status i techenie osteoporoza u zhenschin s defitsitom androgenov v postmenopauze. Vrach. 2015; 3: 28–32 [Strukov V., Elistratov D., Balykova L. et al. Effect of Osteomed Forte on hormonal status and course of osteoporosis in postmenopausal women with androgen deficiency. Vrach. 2015; 3: 28–32 (in Russ.)].
- Ismailova O., Eremina N., Strukov V. i dr. Lechenie hronicheskogo generalizovannogo parodontita u zhenschin v postmenopauzal'nom periode s uchetom mineral'noj plotnosti kostnoj tkani. Vrach. 2015; 10: 56–8 [Ismailova O., Eremina N., Strukov V. et al. Treatment for chronic generalized periodontitis in postmenopausal women in terms of bone mineral density. Vrach. 2015; 10: 56–8 (in Russ.)].
- Lubenets A. Lechenie povrezhdenij proksimal'nogo otdela bedrennoj kosti u bol'nyh starshej vozrastnoj gruppy. Vrach. 2017; 7: 65–7 [Lubenets A. Treatment of proximal femur injuries in older age group patients. Vrach. 2017; 7: 65–7 (in Russ.)].
- Strukov V., Kislov A., Elistratov D. i dr. Personifitsirovannyj podhod v terapii osteoporoza u pozhilyh. Vrach. 2015; 6: 51–3 [Strukov V., Kislov A., Elistratov D. et al. Personified approach in the therapy of osteoporosis in elderly patients. Vrach. 2015; 6: 51–3 (in Russ.)].