Bioimpedance method as a tool for early detection of the risk of neoplasms in the mammary gland

DOI: https://doi.org/10.29296/25877305-2021-10-13
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Issue: 
10
Year: 
2021

Associate Professor P. Seliverstov(1), Candidate of Medical Sciences; N. Gavrilova(2),
Candidate of Medical Sciences; L. Savina(3, 4); О. Аmosova(5); A. Yastrebov(6, 7); I. Chizh(5), Candidate of
Medical Sciences; Associate Professor A. Тishkov(5), Candidate of Physical and Mathematical Sciences (1)I.I.
Mechnikov North-Western State Medical University, Ministry of Health of Russia, Saint Petersburg;
(2)«Medical center «MSCh-24»», Saint Petersburg; (3)Marine Medical Center, Saint Petersburg; (4)Obstetric
College, Saint Petersburg; (5)The First St. Petersburg State Medical University named after Academician I.P.
Pavlov Ministry of Health of Russia, Saint Petersburg; (6)Saint Petersburg State Electrotechnical University
(LETI), Ministry of Science and Higher Education of Russia; (7)Intelligent software systems, Saint
Petersburg

The widespread increase in the number of breast cancer patients, the relevance of prevention and timely therapy issues determine the need to search for a new strategy in the diagnosis of the disease at the preclinical stage. One of the promising directions is the use of a portable mammography for both mass examinations and self-examination of women. The purpose of the study. Evaluation of the effectiveness of the bioimpedance method for detecting the risk of breast neoplasms in accordance with established standards (BIRADS scale) using a portable «smart» mammography. Materials and methods. The study was conducted with the participation of 78 women with breast cancer, who were additionally examined using a portable bioimpedance mammography specially designed for rapid breast screening and identifying the risk of neoplasms without the participation of a specialist (doctor) and complex data decoding. The results of the studies showed a high informative value of the method, sufficient sensitivity and specificity (more than 0.75). Conclusion. The effectiveness of the use of the bioimpedance method in combination with artificial intelligence (AI) in the examination of women with breast neoplasms was confirmed, which made it possible to create a device for very preventive examinations and for self-examination of women at home.

Keywords: 
oncology
breast cancer
screening
mammography
prevention



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References: 
  1. 1. Bludov A.B., Kochergina N.V., Schipahina Ja.A. i dr. Informatsionnye sistemy i telemeditsina: sovremennye vozmozhnosti uluchshenija skrininga raka molochnoj zhelezy. Diagnosticheskaja i interventsionnaja radiologija. 2017; 11 (4): 16–24 [Bludov A.B., Kochergina N.V., Schipahina Ya.A. et al. Information systems and telemedicine: modern possibilities for improving of breast cancer screening. Journal Diagnostic & interventional radiology. 2017; 11 (4); 16–24 (in Russ.)]. DOI: 10.25512/DIR.2017.11.4.02
  2. 2. Bludov A.B., Kochergina N.V., Schipahina Ja.L. i dr. Komp'juterizovannaja sistema mammograficheskogo skrininga. Meditsinskaja fizika. 2017; 76 (4): 65–74 [Bludov A.B., Kochergina N.V., Schipahina Y.A. et al. Computerized mammographic screening system. Meditsinskaya fizika. 2017; 76 (4): 65–74 (in Russ.)].
  3. 3. Zaharova N.A., Semiglazov V.F., Duffy S.W. Skrining raka molochnoj zhelezy: problemy i reshenija. M.: GEOTAR-Media, 2011; 176 s. [Zakharova N.A., Semiglazov V.F., Duffy S.W. Skrining raka molochnoi zhelezy: problemy i resheniya. M.: GEOTAR-Media, 2011; 176 s. (in Russ.)].
  4. 4. Ivanov V.G. Epidemiologicheskie faktory riska, rannjaja diagnostika raka molochnoj zhelezy. Prakticheskaja onkologija. 2002; 3 (1): 1–5 [Ivanov V.G. Epidemiologicheskie faktory riska, rannyaya diagnostika raka molochnoi zhelezy. Prakticheskaya onkologiya. 2002; 3 (1): 1–5 (in Russ.)].
  5. 5. Kaprin A.D., Starinskij V.V., Petrova G.V. (red.). Zlokachestvennye novoobrazovanija v Rossii v 2016 godu (zabolevaemost' i smertnost'). M.: MNIOI im. P.A. Gertsena – filial FGBU «NMITs radiologii» Minzdrava Rossii, 2018 [Kaprin A.D., Starinskii V.V., Petrova G.V. (red.). Zlokachestvennye novoobrazovaniya v Rossii v 2016 godu (zabolevaemost’ i smertnost’). M.: MNIOI im. P.A. Gertsena – filial FGBU «NMITs radiologii» Minzdrava Rossii, 2018 (in Russ.)].
  6. 6. Kochergina N.V., Ivankina O.V., Zamogil'naja Ja.A. i dr. Pervye rezul'taty distantsionnogo mammograficheskogo skrininga raka molochnoj zhelezy. Rossijskij onkologicheskij zhurnal. 2014; 19 (3): 15–8 [Kochergina N.V., Ivankina O.V., Zamogilnaya Y.A. et al. The initial results of remote mammography breast cancer screening. Russian Journal of Oncology. 2014; 19 (3): 15–8 (in Russ.)]. DOI: 10.17816/onco40041
  7. 7. Kochergina N.V., Bludov A.B., Schipahina Ja.A. i dr. Novye napravlenija uluchshenija skrininga raka molochnoj zhelezy. Vestnik rentgenologii i radiologii. 2016; 97 (6): 333–9 [Kochergina N.V., Bludov A.B., Shchipakhina Ya.A. et al. New directions for improvement of breast cancer screening. Journal of radiology and nuclear medicine. 2016; 97 (6): 333–9 (in Russ.)]. DOI: 10.20862/0042-4676-2016-97-6-333-339
  8. 8. Mammologija. Natsional'noe rukovodstvo. Pod red. A.D. Kaprina, N.I. Rozhkova. M.: GEOTAR-Media, 2016; 483 s. [Mammologiya. Natsional’noe rukovodstvo. Pod red. A.D. Kaprina, N.I. Rozhkova. M.: GEOTAR-Media, 2016; 483 s. (in Russ.)].
  9. 9. Morozov S.P., Vladzimirskij A.V., Ledihova N.V. i dr. Telemeditsinskie tehnologii (teleradiologija) v sluzhbe luchevoj diagnostiki. Serija «Luchshie praktiki luchevoj i instrumental'noj diagnostiki». M., 2018; 58 s. [Morozov S.P., Vladzimirskii A.V., Ledikhova N.V. et al. Telemeditsinskie tekhnologii (teleradiologiya) v sluzhbe luchevoi diagnostiki. Seriya «Luchshie praktiki luchevoi i instrumental’noi diagnostiki». M., 2018; 58 s. (in Russ.)].
  10. 10. Podchinenova D.V., Samojlova Ju.G., Kobjakova O.S. i dr. Neinvazivnyj sposob prognozirovanija insulinorezistentnosti na osnovanii dannyh bioimpedansometrii. Pediatrija. 2019; 98 (6): 86–90 [Podchinenova D.V., Samoilova Yu.G., Kobyakova O.S. et al. Method for non invasive screening of insulin resistance based on bioimpedance measurement data. Pediatria. 2019; 98 (6): 86–90 (in Russ.)]. DOI: 10.24110/0031-403X-2019-98-6-86-90
  11. 11. Samojlova Ju.G., Kudlaj D.A., Podchinenova D.V. i dr. Bioimpedansometrija kak metod diagnostiki vistseral'nogo ozhirenija v pediatricheskoj praktike. Molekuljarnaja meditsina. 2019; 17 (6): 26–31 [Samoilova Yu.G., Kudlay D.A., Podchinenova D.V. et al. Bioimpendancemetria as a method for diagnosis of visceral obesity in pediatric practice. Molecular medicine. 2019; 17 (6): 26–31 (in Russ.)]. DOI: 10.29296/24999490-2019-06-05
  12. 12. Jastrebov A.V., Gavrilova N.P. Novye podhody k profilaktike raka molochnoj zhelezy s ispol'zovaniem bytovogo portativnogo mammografa. Sb. mat-lov VIII Vseross. s mezhdunar. uchast. zaochnoj nauchno-prakt. konf. Pod red. V.S. Luchkevicha. Ch.2. SPb, 2021; s. 425 [Yastrebov A.V., Gavrilova N.P. Novye podkhody k profilaktike raka molochnoi zhelezy s ispol’zovaniem bytovogo portativnogo mammografa. Sb. mat-lov VIII Vseross. s mezhdunar. uchast. zaochnoi nauchno-prakt. konf. Pod red. V.S. Luchkevicha. Ch.2. SPb, 2021; s. 425 (in Russ.)].
  13. 13. Portnoj S.M. Osnovnye riski razvitija raka molochnoj zhelezy i predlozhenija po ego profilaktike. Opuholi zhenskoj reproduktivnoj sistemy. 2018; 14 (3): 25–39 [Portnoy S.M. Main risk factors for breast cancer and proposals for its prevention. Tumors of female reproductive system. 2018; 14 (3): 25–39 (in Russ.)]. DOI: 10.17650/1994-4098-2018-14-3-25-39
  14. 14. Jastrebov A.V., Trofimov P.M., Amosova O.V. i dr. Raspredelenija bioimpedansa v tkanjah molochnoj zhelezy s novoobrazovaniem (modelirovanie i eksperiment). Voprosy radioelektroniki. 2020; 2: 16–22 [Yastrebov A.V., Trofimov P.M., Amosova O.V. et al. Distributions of bioimpedance in breast tissue with neoplasm (modeling and experiment). Issues of radio electronics. 2020; 2: 16–22 (in Russ.)]. DOI: 10.21778/2218-5453-2020-2-16-22
  15. 15. Seliverstov P.V., Bakaeva S.R., Shapovalov V.V. Otsenka riskov sotsial'no znachimyh hronicheskih neinfektsionnyh zabolevanij c ispol'zovaniem telemeditsinskoj sistemy. Vrach. 2020; 31 (10): 68–73 [Seliverstov P., Bakaeva S., Shapovalov V. A telemedicine system in the assessment of risks for socially significant chronic non-communicable diseases. Vrach. 2020; 31 (10): 68–73 (in Russ.)]. DOI: 10.29296/25877305-2020-10-13
  16. 16. Rozhkova N.I., Kaprin A.D. (red.). Profilaktika – prioritet klinicheskoj mammologii. M.: SIMK, 2015 [Rozhkova N.I., Kaprin A.D. (red.). Profilaktika – prioritet klinicheskoi mammologii. M.: SIMK, 2015 (in Russ.)].
  17. 17. Stenina M. B., Zhukova L. G., Koroleva I. A. i dr. Prakticheskie rekomendatsii po lekarstvennomu lecheniju raka molochnoj zhelezy. Zlokachestvennye opuholi. 2020; 10 (3s2-1): 145–82 [Stenina M. B., Zhukova L. G., Koroleva I. A. et al. Prakticheskie rekomendatsii po lekarstvennomu lecheniyu raka molochnoi zhelezy. Malignant Tumours. 2020; 10 (3s2-1): 145–82 (in Russ.)]. DOI: 10.18027/2224-5057-2020-10-3s2-09
  18. 18. Fisenko E.P. Metodika provedenija UZI molochnyh zhelez. Serija «Luchshie praktiki luchevoj i instrumental'noj diagnostiki». M., 2019; 36 s. [Fisenko E.P. Metodika provedeniya UZI molochnykh zhelez. Seriya «Luchshie praktiki luchevoi i instrumental’noi diagnostiki». M., 2019; 36 s. (in Russ.)].
  19. 19. Chesnokova N.P., Barsukov V.Ju., Plohov V.N. Faktory riska razvitija raka molochnoj zhelezy. Uspehi sovremennogo estestvoznanija. 2008; 1: 30–6 [Chesnokova N.P., Barsukov V.Yu., Plokhov V.N. Risk factors of breast cancer development. Advances in current natural sciences. 2008; 1: 30–6 (in Russ.)].
  20. 20. Amin A., Sbriver C., Henry L. et al. Breast cancer screening compliance among young women in a free access healthcare system. J Surg Oncol. 2008; 97 (1): 20–4. DOI: 10.1002/jso.20895
  21. 21. Mainiero M.V., Lourenco A., Mahoney M.S. et al. ACR Appropriateness Criteria Breast Cancer Screening. J Am Coll Radiol. 2016; 13 (11S): R45–R49. DOI: 10.1016/j.jacr.2016.09.021
  22. 22. Monticciolo D.L., Newell M.S., Moy L. et al. Breast Cancer Screening in Women at Higher-Than-Average Risk; Recommendations From the ACR. J Am Coll Radiol. 2018; 15 (3 Pt A): 408–14. DOI: 10.1016/j.jacr.2017.11.034
  23. 23. Yastrebov A.V., Trofimov P.M., Osadchy V.N. et al. Portable home use mammograph for detection breast tumors. AIP Conference Proceedings. 2019; 2140 (1): 020079. DOI: 10.1063/1.5122004
  24. 24. Tabar L., Vitak B., Chen H.H. et al. The Swedish two-country trial twenty longs term follow up. Radiol Clin North Am. 2000; 38 (4): 625–51. DOI: 10.1016/s0033-8389(05)70191-3