Quality of life and rehabilitation technologies in patients with external genital endometriosis

DOI: https://doi.org/10.29296/25877305-2021-08-02
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Issue: 
8
Year: 
2021

E. Begovich(1); Professor A. Solopova(1), MD; L. Idrisova(1), Candidate of Medical Sciences; S.
Khlopkova(2) (1)I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of
Health of Russia (2)L.A. Vorokhobov City Clinical Hospital Sixty-Seven, Moscow Healthcare Department

External genital endometriosis is a disease that requires the timely integration of complex treatment and personalized rehabilitation technologies that allow not only to restore lost body functions, but also to improve psycho-emotional, sexual and social status, as well as improve the quality of life. The purpose of this review is to analyze modern scientific medical literature, both domestic and foreign, to systematize data on the use of new methods of patient management and rehabilitation. For all patients with external genital endometriosis, it is necessary to develop long-term management programs and full-scale restorative and recreational methods, as part of a multidisciplinary approach.
Keywords: 
gynecology
endometriosis
rehabilitation
quality of life

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References: 
  1. Pérez-López F.R., Lia O., Perez-Roncero G.R. et al. The effect of endometriosis on sexual function as assessed with the Female Sexual Function Index: systematic review and meta-analysis. Gynecol Endocrinol. 2020; 36 (11): 1015–23. DOI: 10.1080/09513590.2020.1812570
  2. Tovmach L.N., Mihina I.V. Problemy i perspektivy razvitija i finansirovanija zdravoohranenija v Rossijskoj Federatsii. Vestnik TGU. 2015; 20 (4): 795–7 [Tovmach L.N., Mikhina I.V. Problems and prospects of public health development and financing in Russian Federation. Vestnik TGU. 2015; 20 (4): 795–7 (in Russ.)].
  3. Mishra V.V., Pradeep B., Ritu A. et al. Prevalence, clinical and laparoscopic features of endometriosis among infertile women. J Obstet Gynaecol India. 2017; 67 (3): 208–12. DOI: 10.1007/s13224-016-0931-x
  4. Mozokina S.L. Meditsinskaja reabilitatsija i sanatorno-kurortnoe lechenie. Teorija i praktika servisa: ekonomika, sotsial'naja sfera, tehnologii. 2015; 4 (26): 65–8 [Mozokina S.L. Medical rehabilitation and sanatorium treatment. Teoriya i praktika servisa: ekonomika, sotsialnaya sfera, technologii. 2015; 4 (26): 65–8 (in Russ.)].
  5. Vlasina A.Ju., Solopova A.G., Son E.A. i dr. Psihoemotsional'noe blagopoluchie i seksual'naja funktsija bol'nyh pogranichnymi opuholjami jaichnikov. Akusherstvo, ginekologija i reproduktsija. 2020; 14 (5): 551–67 [Vlasina A.Yu., Solopova A.G., Son E.A. et al. Psycho-emotional well-being and sexual function of patients with borderline ovarian tumors. Obstetrics, Gynecology and Reproduction. 2020; 14 (5): 551–67 (in Russ.)]. DOI: 10.17749/2313-7347/ob.gyn.rep.2020.147
  6. Solopova A.G., Vlasina A.Ju., Idrisova L.E. Reabilitatsija onkoginekologicheskih bol'nyh: aktual'nye problemy i vozmozhnye reshenija. Vestnik vosstanovitel'noj meditsiny. 2019; 5 (93): 87–96 [Solopova A.G., Vlasina A.Y., Idrisova L.E. et al. Rehabilitation of oncogynecological patients: current problems and possible solutions rehabilitation of oncogynecological patients: current problems and possible solutions. Vestnik vosstanovitel’noy medicini. 2019; 5 (93): 87–96 (in Russ.)].
  7. Soliman A.M., Coyne K.S., Zaiser E. et al. The burden of endometriosis symptoms on health- related quality of life in women in the United States: a cross-sectional study. J Psychosom Obstet Gynaecol. 2017; 38 (4): 238–48. DOI: 10.1080/0167482X.2017.1289512
  8. Orazov M.R., Nosenko E.N., Pokul' L.V. Seksual'naja funktsija zhenschin s endometriozom. «Kogda ljubov' prichinjaet bol'»: sistematicheskij obzor vlijanija hirurgicheskogo i medikamentoznyh metodov lechenija endometrioza na seksual'nuju funktsiju zhenschin. Akusherstvo i ginekologija. Novosti. Mnenija. Obuchenie. 2017; 3 (17): 133–43 [Orazov M.R., Nosenko E.N., Pokul’ L.V. Sexual function of women with endometriosis. «When love hurts»: a systematic review of the impact of surgical and medical methods of the treatment sexual function of women with endometriosis. Akusherstvo i ginekologiya. Novosti. Mneniya. Obucheniye. 2017; 3 (17): 133–43 (in Russ.)]. DOI: 10.24411/2303-9698-2017-00046
  9. Fassbender A., Burney R.O., Dorien F.O. et al. Update on biomarkers for the detection of endometriosis. Biomed Res Int. 2015; 2015: 130854. DOI: 10.1155/2015/130854
  10. Balan V.E., Orlova S.A., Titchenko Ju.P. i dr. Neinvazivnye markery endometrioza i dinamika ih urovnja na fone gormonal'noj terapii. Problemy reproduktsii. 2018; 24 (5): 77–81 [Balan V.E., Orlova S.A., Titchenko Iu.P. et al. Noninvasive markers of endometriosis and their dynamics during hormone therapy. Russian Journal of Human Reproduction. 2018; 24 (5): 77–81 (in Russ.)]. DOI: 10.17116/repro20182405177
  11. Dorien F.O., Fassbender A., Van Bree R. et al. Technical verification and assessment of independent validation of biomarker models for endometriosis. Biomed Res Int. 2019; 2019: 367306. DOI: 10.1155/2019/3673060
  12. Lee Y., Lee Y., Lee S. et al. Correlation of preoperative biomarkers with severity of adhesion in endometriosis. J Gynecol Obstet Hum Reprod. 2020; 49 (1): 101637. DOI: 10.1016/j.jogoh.2019.101637
  13. Sulima A.N., Davydova A.A., Jakovchuk E.K. Provospalitel'nye tsitokiny v tkani tazovyh peritoneal'nyh spaek u zhenschin reproduktivnogo vozrasta s naruzhnym genital'nym endometriozom. Krymskij zhurnal eksperimental'noj i klinicheskoj meditsiny. 2015; 4 (20): 39–42 [Sulima A.N., Davydova A.A., Yakovchuk E.K. Proinflammatory cytokines in the pelvic peritoneal adhesions tissues’ of reproductive age women with external genital. Krymskiy zhurnal eksperimental’noj i klinicheskoy mediciny. 2015; 4 (20): 39–42 (in Russ.)].
  14. Jiang J., Jiang Zh., Xue M. Serum and peritoneal fluid levels of interleukin-6 and interleukin-37 as biomarkers for endometriosis. Gynecol Endocrinol. 2019; 35 (7): 571–5. DOI: 10.1080/09513590.2018.1554034
  15. Orazov M.R., Radzinskij V.E., Hamoshina M.B. i dr. Kontsentratsija vitamina D u zhenschin s tazovoj bol'ju, obuslovlennoj ovarial'nym endometriozom. Akusherstvo i ginekologija Sankt-Peterburga. 2017; 4: 57–61 [Orazov M.R., Radzinskiy V.Y., Khamoshina M.B. et al. The concentration of vitamin d in women with pelvic pain caused by ovarian endometriosis. Obstetrics and Gynaecology of Saint-Petersburg. 2017; 4: 57–61 (in Russ.)].
  16. Collinet P., Fritel X., Revel-Delhom C. et al. Management of endometriosis: CNGOF/HAS clinical practice guidelines - short version. J Gynecol Obstet Hum Reprod. 2018; 47 (7): 265–74. DOI: 10.1016/j.jogoh.2018.06.003
  17. Kozachenko A.V. Gormonal'naja terapija bol'nyh endometriozom – sovremennoe sostojanie problemy (obzor literatury). Meditsinskij sovet. 2020; 13: 116–23 [Kozachenko A.V. Hormone therapy for patients with endometriosis: status update on the problem (literature review). Meditsinskiy sovet = Medical Council. 2020; 13: 116–23 (in Russ.)]. DOI: 10.21518/2079-701X-2020-13-116-123
  18. Lagana A.S., La Rosa V.L., Rapisarda A.M.C. et al. Anxiety and depression in patients with endometriosis: impact and management challenges. Int J Womens Health. 2017; 9: 323–30. DOI: 10.2147/IJWH.S119729
  19. Caruso S., Iraci M, Cianci S. et al. Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest. J Endocrinol Invest. 2015; 38 (11): 1211–8. DOI: 10.1007/s40618-015-0383-7
  20. Taylor H.S., Giudice L.C., Lessey B.A. et al. Treatment of endometriosis-associated pain with elagolix, an oral GnRH antagonist. N Engl J Med. 2017; 377: 28–40. DOI: 10.1056/NEJMoa1700089
  21. Nicholas L., Hugh S.T., David F.A. et al. Elagolix reduced dyspareunia and improved health-related quality of life in premenopausal women with endometriosis-associated pain. JEPPD. 2019; 11 (4): 171–80. DOI: 10.1177/2284026519872401
  22. Lukic A., Di Properzio M., De Carlo S. et al. Quality of sex life in endometriosis patients with deep dyspareunia before and after laparoscopic treatment. Arch Gynecol Obstet. 2016; 293 (3): 583–90. DOI: 10.1007/s00404-015-3832-9
  23. Leonardo-Pinto J.P., Benetti-Pinto C.L., Yela D.A. When solving dyspareunia is not enough to restore sexual function in women with deep infiltrating endometriosis treated with dienogest. J Sex Marital Ther. 2019; 45 (1): 44–9. DOI: 10.1080/0092623X.2018.1474411
  24. Del Forno S., Arena A., Alessandrini M. et al. Transperineal ultrasound visual feedback assisted pelvic floor muscle physiotherapy in women with deep infiltrating endometriosis and dyspareunia: a pilot study. J Sex Marital Ther. 2020; 46 (7): 603–11. DOI: 10.1080/0092623X.2020.1765057
  25. Farshi N., Hasanpour S., Mirghafourvand M. et al. Effect of self-care counselling on depression and anxiety in women with endometriosis: a randomized controlled trial. BMC Psychiatry. 2020; 20 (1): 391. DOI: 10.1186/s12888-020-02795-7
  26. van Aken M.A.W., Oosterman J.M., van Rijn C.M. et al. Pain cognition versus pain intensity in patients with endometriosis: toward personalized treatment. Fertil Steril. 2017; 108 (4): 679–86. DOI: 10.1016/j.fertnstert.2017.07.016
  27. Alshehre S.M., Duffy Sh., Jones G. et al. A prospective, single-centre, single-arm, open label study of the long-term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain. Reprod Biol Endocrinol. 2020; 18 (1): 28. DOI: 10.1186/s12958-020-00586-z
  28. Yang Xu, Wenli Zhao, Te Li et al. Effects of acupuncture for the treatment of endometriosis-related pain: a systematic review and meta-analysis. PLoS One. 2017; 12 (10): 0186616. DOI: 10.1371/journal.pone.0186616
  29. Ruining Liang, Peishuang Li, Xuemei Peng et al. Efficacy of acupuncture on pelvic pain in patients with endometriosis: study protocol for a randomized, single-blind, multi-center, placebo-controlled trial. Trials. 2018; 19 (1): 314. DOI: 10.1186/s13063-018-2684-6
  30. de Sousa T.R., de Souza B.C., Zomkowisk K. et al. The effect of acupuncture on pain, dyspareunia, and quality of life in Brazilian women with endometriosis: A randomized clinical trial. Complement Ther Clin Pract. 2016; 25: 114–21. DOI: 10.1016/j.ctcp.2016.09.006
  31. Vasconcelos Goncalves A., Makuch M.Y., Setubal M.S. et al. A qualitative study on the practice of yoga for women with pain-associated endometriosis. J Altern Complement Med. 2016; 22 (12): 977–82. DOI: 10.1089/acm.2016.0021
  32. Kononov S.N., Shkljar A.A., Kozachenko A.V. i dr. Formirovanie spaek pri endometrioze i puti ih profilaktiki (obzor literatury). Problemy reproduktsii. 2015; 21 (2): 82–7 [Kononov S.N., Shklyar A.A., Kozachenko A.V. et al. Endometriosis adhesions formation and their prevention (a review). Russian Journal of Human Reproduction. 2015; 21 (2): 82–7 (in Russ.)]. DOI: 10.17116/repro201521282-87
  33. El-Monsif Thabet A.A., Alshehri M.A. Effect of pulsed high-intensity laser therapy on pain, adhesions, and quality of life in women having endometriosis: a randomized controlled trial. Photomed Laser Surg. 2018; 36 (7): 363–9. DOI: 10.1089/pho.2017.4419
  34. Rindos N.B., Fulcher I.R., Donnellan N.M. Pain and quality of life after laparoscopic excision of endometriosis. J Minim Invasive Gynecol. 2020; 27 (7): 1610–7. DOI: 10.1016/j.jmig.2020.03.013
  35. Mira T.A.A., Giraldo P.C., Yela D.A. et al. Effectiveness of complementary pain treatment for women with deep endometriosis through transcutaneous electrical nerve stimulation (TENS): randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2015; 194: 1–6. DOI: 10.1016/j.ejogrb.2015.07.009
  36. Mira T.A.A., Yela D.A., Podgaec S. et al. Hormonal treatment isolated versus hormonal treatment associated with electrotherapy for pelvic pain control in deep endometriosis: randomized clinical trial. Eur J Obstet Gynecol Reprod Biol. 2020; 255: 134–41. DOI: 10.1016/j.ejogrb.2020.10.018
  37. En'kova E.V., Korotkih I.N., Frolov M.V. Issledovanie fagotsitarnoj aktivnosti naruzhnogo genital'nogo endometrioza kak markera kletochnogo zvena immuniteta. Meditsinskij vestnik severnogo Kavkaza. 2015; 10 (4): 376–9 [Enkova E.V., Korotkikh I.N., Frolov M.V. Investigation of the exturnal genital endometriosis fagocite activity as the cellular immunity marker. Medical news of North Caucasus. 2015; 10 (4): 376–9 (in Russ.)]. DOI: 10.14300/mnnc.2015.10092
  38. Ahkubekova N.K., Ovsienko A.B., Tereshin A.T. i dr. Dinamika pokazatelej tsitokinovogo statusa u bol'nyh naruzhnym genital'nym endometriozom v rannem posleoperatsionnom periode pod vozdejstviem radonoterapii i agonistov gonadoliberina. Meditsinskij vestnik severnogo Kavkaza. 2018; 13 (1.1): 32–5 [Ahkubekova N.K., Ovsienko A.B., Tereshin A.T. et al. Dynamics of the cytokine status indicators in patients with external genital endometriosis in early postoperative period under the influence of radon theraphy and gnrh agonists. Medical news of North Caucasus. 2018; 13 (1.1): 32–5 (in Russ.)]. DOI: 10.14300/mnnc.2018.13009
  39. Ahkubekova N.K., Kajsinova A.S., Fedorov A.A. i dr. Kompleksnoe bal'neolechenie v kachestve terapii prikrytija na fone antigormonal'nogo vozdejstvija agonistami gonadotropin-rilizing gormona u zhenschin s naruzhnym endometriozom. Voprosy kurortologii, fizioterapii i lechebnoj fizicheskoj kul'tury. 2018; 95 (5): 31–9 [Akhkubekova N.K., Kaisinova A.S., Fedorov A.A. et al. The role of the combined balneotherapeutic treatment as the «add-back therapy» against the background of the anti-hormonal effects of the agonists of gonadotropin-releasing hormone in the women suffering from endometriosis genitalis externa. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury. 2018; 95 (5): 31–9 (in Russ.)]. DOI: 10.17116/kurort20189505131