The possibilities of using the topical anesthetic cream Anesta-A in cosmetology

DOI: https://doi.org/10.29296/25877305-2021-02-13
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Issue: 
2
Year: 
2021

T. Potupchik(1), Candidate of Medical Sciences, E. Kangun(2), E. Shpakova(2) (1)Prof. V.F.
Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia 2«Triumph» Aesthetic
Medicine Clinic, Krasnoyarsk

The paper analyzes the mechanism of action, efficacy, and safety of the topical anesthetic Anesta®-A for topical local application in cosmetology. It gives the data of a comparative study of using the drug in various cosmetic manipulations and shows the advantages of the cream with lidocaine/prilocaine combination versus other topical local anesthetics (TLA). The proven analgesic effect and good safety profile of the cream Anesta®-A allow the latter to be considered as a first-line and optimal drug from the TLA group for various invasive procedures.
Keywords: 
dermatology
topical local anesthetics
invasive cosmetic manipulations
lidocaine/prilocaine
Anesta-A

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References: 
  1. Gosudarstvennyj reestr lekarstvennyh sredstv. Elektronnyj resurs. [State Register of medicinal products. Electronic resource (in Russ.)]. Rezhim dostupa / Access mode: https://grls.rosminzdrav.ru/Default.aspx
  2. Zhigul'tsova T.I., Parkaeva L.V., Il'ina E.E. i dr. Opyt primenenija 5% krema Emla v praktike dermatokosmetologa. Russkij meditsinskij zhurnal. 2008; 16 (8): 570–1 [Zhigultsova T.I., Parkaeva L.V., Ilina E.E. et al. Experience of using 5% Emla cream in the practice of a dermatocosmetologist. Russian Medical Journal. 2008; 16 (8): 570–1 (in Russ.)].
  3. Zaradej I.I., Ljutsko V.V. Metodiki provedenija anestezii pri vypolnenii diagnosticheskih i lechebnyh manipuljatsij v dermatologii. Sovremennye problemy zdravoohranenija i meditsinskoj statistiki. 2015; 4: 33–44 [Zaradey I.I., Lutsko V.V. The techniques of anesthesia when performing diagnostic and therapeutic procedures in dermatology. Sovremennye problemy zdravookhraneniya i meditsinskoi statistiki. 2015; 4: 33–44 (in Russ.)].
  4. Kalvi T.N., Uil'jams N.E. Farmakologija dlja anesteziologa. Kniga pervaja. M.? 2007. [Calvey T.N., Williams N.E. Principles and Practice of Pharmacology for Anaesthetists. Blackwell Publishing; M., 2007 (in Russ.)].
  5. Matushevskaja E.V., Svirschevskaja E.V., Matushevskaja Ju.I. i dr. Topicheskie mestnye anestetiki v kosmetologii. Klinicheskaja dermatologija i venerologija. 2017; 3: 89–96 [Matushevskaya E.V., Svirshchevskaya E.V., Matushevskaya Yu.I. et al. Topical local anesthetics in cosmetology. Clinical Dermatology and Venereology. 2017; 3: 89–96 (in Russ.)]. https://doi.org/10.17116/klinderma201716389-96
  6. Oparin R.B. Anesteziologicheskoe soprovozhdenie protsedur v dermatologicheskoj praktike. Russkij meditsinskij zhurnal. 2009; 6: 404 [Oparin R.B. Anesthesiological support of procedures in dermatological practice. Russian Medical Journal. 2009; 6: 404 (in Russ.)].
  7. Ranneva E.A. Primenenie krema Emla v kompleksnoj korrektsii kosmeticheskih nedostatkov. Eksperimental'naja klinicheskaja dermatokosmetologija. 2010; 2: 48–53 [Ranneva E.A. The use of Emla cream in the complex correction of cosmetic defects. Experimental clinical dermatocosmetology. 2010; 2: 48–53 (in Russ.)].
  8. Terent'eva L.V. Anesta®-A: vstrechaem novyj preparat dlja poverhnostnoj anestezii. Kosmetika i meditsina. 2020; 3: 1–6 [Terentyeva L. V. Anesta®-A: we meet a new drug for surface anesthesia. Cosmetics and medicine. 2020; 3: 1–6 (in Russ.)].
  9. Sharova A.A., Lebedjuk V.G. Anestezija v dermatokosmetologii. Eksperimental'naja i klinicheskaja dermatologija. 2010; 5: 36–41 [Sharova A.A., Lebedyuk V.G. Anesthesia in dermatocosmetology. Experimental and clinical dermatology. 2010; 5: 36–41 (in Russ.)].
  10. American Society of Plastic Surgeons ASPS. 2012. URL: https://www.plasticsurgery.org/
  11. Aslaksen P.M., Zwarg M.L., Eilertsen H.I. et al. Opposite effects of the same drug: reversal of topical analgesia by nocebo information. Pain. 2015; 156 (1): 39–46. https://doi.org/10.1016/j.pain.0000000000000004
  12. Greveling K., Prens E.P., Ten Bosch N. et al. Comparison of lidocaine/tetracaine cream and lidocaine/prilocaine cream for local anaesthesia during laser treatment of acne keloidalis nuchae and tattoo removal: results of two randomized controlled trials. Br J Dermatol. 2017; 176 (1): 81–6. https://doi.org/10.1111/bjd.14848.
  13. Horikiri M., Ueda K., Sakaba T. Comparison of Emla cream and topical lidocaine tape for pain relief of V-beam laser treatment. J Plast Surg Hand Surg. 2018; 52 (2): 94–6. DOI: 10.1080/2000656X.2017.1342092
  14. Koppel R.A., Coleman K.M., Coleman W.P. The efficacy of EMLA versus ELA Max for pain relief in medium-depth chemical peeling: a clinical and histopathologic evaluation. Dermatol Surg. 2000; 26 (1): 61–4. DOI: 10.1046/j.1524-4725.2000.99211.x
  15. Lee S.H., Pakdeethai J., Toh M.P. et al. A Double-Blind, Randomised, Placebo-Controlled Trial of EMLA Cream (Eutectic Lidocaine/Prilocaine Cream) for Analgesia Prior to Cryotherapy of Plantar Warts in Adults. Ann Acad Med Singapore. 2014; 43 (10): 511–4.
  16. Shamriz O., Cohen-Glickman I., Reif Sh. et al. Methemoglobinemia induced by lidocaine-prilocaine cream. Isr Med Assoc. 2014; 16 (4): 250–4.
  17. You P., Yuan R., Chen C. Design and evaluation of lidocaine- and prilocaine-coloaded nanoparticulate drug delivery systems for topical anesthetic analgesic therapy: a comparison between solid lipid nanoparticles and nanostructured lipid carriers. Drug Des Devel Ther. 2017; 11: 2743–52. DOI: 10.2147/DDDT.S141031