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The role of diabetes mellitus and a gender factor in the development of a second noncardioembolic ischemic stroke


V. Shishkova(1, 2), Candidate of Medical Sciences; Professor T. Adasheva(2), MD; Professor L.
Stakhovskaya(3), MD (1)Center for Speech Pathology and Neurorehabilitation, Moscow Healthcare Department
(2)A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia (3)N.I.
Pirogov Russian National Research Medical University, Moscow

Objective. To analyze the frequency and date of onset of a secondary noncardioembolic ischemic stroke (IS) over a three-year period according to a patient’s gender and the presence of diabetes mellitus (DM). Subjects and methods. The cohort observational study covered 206 patients who had experienced a first noncardioembolic IS. The clinical and metabolic parameters were studied in the participants, as well as the frequency and date of onset of a secondary IS were assessed using the Cutler-Ederer and Kaplan-Meier methods according to gender and DM. Results. The analysis of the frequency and date of onset of a second noncardioembolic IS over a three-year period showed an increase in the risk of this pathology in both male patients and type 2 diabetes (T2DM) ones. Conclusion. Male patients and T2DM ones are at a high risk for a secondary noncardioembolic IS.

non-cardioembolic ischemic stroke
diabetes mellitus
male sex

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