The Journal is included in Russian and International Library and Abstract Databases
Russain Science Index (Russia)
EBSCO
DOI Registration Agency (USA)

Treatment for neonatal respiratory distress syndrome in extremely low-birth weight prema-ture infants: selection of respiratory support

DOI: https://doi.org/10.29296/25877305-2020-08-09
Issue: 
8
Year: 
2020

O. Zavyalov(1, 2); V. Marenkov(1); A. Dementyev(1, 3), Candidate of Medical Sciences; Professor
I. Pasechnik(2), MD (1)S.S. Yudin City Clinical Hospital, Moscow (2)Central State Medical Academy,
Presidential Administration of the Russian Federation, Moscow (3)Russian Medical Academy of Continuing
Professional Education, Moscow

The paper deals with the urgent problem of perinatology and neonatal resuscitation - the treatment of extremely premature infants with neonatal respiratory distress syndrome (NRDS). It discusses the epidemiology, survival, and perinatal outcomes in premature babies. NRDS is a se-vere respiratory disorder in premature babies due to immaturity of the lungs and primary surfac-tant deficiency. The paper shows the high sociomedical significance of the impact of gestational age and extremely low-birth weight on the severity and progression of respiratory failure in ex-tremely premature infants. It presents the clinical manifestations and features of the diagnosis of NRDS. The Silverman-Andersen respiratory severity score is applied. The paper discusses the modern principles of and approaches to performing a starting and prolonged respiratory therapy as mechanical ventilation with biphasic positive airway pressure (BIPAP). The authors give their preliminary results of using non-invasive mechanical ventilation in the duoPAP mode, an analogue of BIPAP through nasal cannulas. They consider indications, contraindications, and predictors of effective use of duoPAP in a in extremely low-birth weight premature infant within the first hours and days.

Keywords: 
perinatology
neonatology
premature newborns
extremely low-birth weight
neonatal respiratory distress syndrome
respiratory failure
non-invasive mechanical ventilation
neonatal intensive care
respiratory support
surfactant
premature birth



References: 
  1. Neonatologija: Natsional'noe rukovodstvo. Pod red. N.N. Volodina. M.: GEOTAR-Media, 2009; 848 s. [Neonatology: national leadership. Ed. N.N.Volodin. M.: GEOTAR-Media, 2009; 848 r. (in Russ.)].
  2. Akusherstvo: uchebnik. Pod red. V.E. Radzinskogo, A.M. Fuksa. M.: GEOTAR-Media, 2016; 1040s. [Obstetrics: a textbook. Ed. V.E. Radzinsky, A.M. Fuchs. M.: GEOTAR-Media, 2016; 1040 p. (in Russ.)].
  3. Strizhakov A.N., Ignatko I.V., Davydov A.I. Akusherstvo: uchebnik. M.: GEOTAR-Media, 2020; 1072 s. [Ctrizhakov A.N., Ignatko I.V., Davydov A.I. Obstetrics: a textbook. M.: GEOTAR-Media, 2020; 1072 pp. (in Russ.)]. DOI: 10.33029/9704-5396–4-2020-AKU-I-1072
  4. Shabalov N.P. Neonatologija: ucheb posobie: v 2 t. 6-e izd. ispr. i dop. M.: GEOTAR-Media, 2019; T.1; 707 s. [Shabalov N.P. Neonatology: textbook: in 2 volumes. 6th ed. M.: GEOTAR-Media, 2019; V.1; 704 p. (in Russ.)].
  5. Patofiziologija: uchebnik po spetsial'nosti «Pediatrija». Pod red P.F. Litvitskogo. M.: GEOTAR-Media, 2020; 856 s. [Pathophysiology: A Textbook in the Speciality «Pediatrics». Ed. P.F. Litvitsky. M.: GEOTAR-Media, 2020; 856 pp. (in Russ.)]. DOI: 10.33029/9704-5365-O-PAT-2020-I-856
  6. Dudenhauzen J.V. Prakticheskoe akusherstvo. Rukovodstvo dlja vrachej. Per s angl. Pod red. A.D. Makatsarija. 21 izd. M.: OOO «Izdatel'stvo «Meditsinskoe informatsionnoe agenstvo», 2019; XVI + 592 s. [Dudenhausen J.W. Practical obstetrics. Aquide for physicians. Transl. From English. Ed. A.D. Macatsaria. 21st ed. M.: LLS Publishing House Medical Information Agency, 2019; XVI + 592 pp. (in Russ.)].
  7. Ovsjannikov D.Ju., Bolibok A.M., Krsheminskaja I.V. i dr. Dokazatel'naja pul'monologija novorozhdennyh i grudnyh detej: uchebnoe posobie. Pod red. D.Ju. Ovsjannikova. 2-e izd., pererab i dop. M.: RUDN, 2017; 168 s. [Ovsyannikov D.Yu., Bolibok A.M., Krsheminskaya I.V. et al Evidence-based pulmonology of newborns and infants:atraining manual. Ed. D.Yu. Ovsyannicov. 2nd ed., rev. and add. M.: RUDN, 2017; 168 p. (in Russ.)].
  8. Vedenie novorozhdennyh s respiratornym distress-sindromom 2015. Klinicheskie rekomendatsii (protokoly) po neonatologii. Red. D.O. Ivanov. SPb: Inform–Navigator, 2016; 464 s. [Management of newborns witn respiratory distress syndrome 2015. Clinical recommendations (Protocols) on neonatology. Ed. D.O. Ivanov. SPb: Inform–Nawigator, 2016; 464 p. (in Russ.)].
  9. Mezhinskij S.S., Karpova A.L., Mostovoj A.V. i dr. Obzor Evropejskih soglasitel'nyh rekomendatsij po vedeniju novorozhdennyh s respiratornym distress sindromom – 2019. Neonatologija: novosti, mnenija, obuchenie. 2019; 7 (3): 46–58 [Mezhinsky S.S, Karpova A.L., Mostovoy A.V. et al. Overview of the European consensus quidelines on tne management of respiratory distress syndrome – 2019. Neonatology: novosti, mneniya, obuchenie = Neonatology: News, Opinions, Training. 2019; 7 (3): 46–58 (in Russ.)]. DOI: 10.24411/ 2308-2402-2019-13006
  10. Kuznetsova I.V., Kolesnichenko A.P., Gritsan A.I. i dr.Osobennosti intensivnoj terapii ostrogo respiratornogo sindroma novorozhdennyh: metodicheskie rekomendatsii dlja IPO. Krasnojarsk: KrasGMU, 2011; 67 s. [Kuznetsova I.V., Kolesnichenko A.P., Gritsan A.I. et al Features of intensive care of acute respiratory distress syndrome of newborn: quidelines for IPO. Krasniyarsk: KrasGMU, 2011; 67 p. (in Russ.)].
  11. Shabalov N.P. Neonatologija: uchebnoe posobie: v 2 t. 6-e izd., ispr. i dop. M.: GEOTAR-Media, 2019; T.2; 736 s. [Shabalov N.P. Neonatology: studygvide: in 2 volumes. 6th ed. M.: GEOTAR-Media, 2019; T.2; 736 p. (in Russ.)].
  12. Respiratornyj distress u novorozhdennyh. Pod red. M.V. Fomicheva. M.: MEDpress-inform, 2017; 504 s. [Respiratory distress in infants. Ed. M.V. Fomicheva. M.: MEDpress-inform, 2017; 504 p. (in Russ.)].
  13. Aleksandrovich Ju.S., Pshenisnov K.V. Respiratornaja podderzhka pri kriticheskih sostojanijah v pediatrii i neonatologii: rukovodstvo dlja vrachej. M.: GEOTAR-Media, 2020; 272 s. [Aleksandrovich Yu.S., Pshenisnov K.V. Respiratory support for critical conditions in pediatrics and neonatology: a quide for doctors. M.: GEOTAR-Media, 2020; 272 pp. (in Russ.)]. DOI: 10.33029/9704-5418-3-IVL-2020-1-272
  14. Gorjachev A.S., Savin I.A. Osnovy IVL. M.: OOO «Aksiom Grafiks Junion», 2019; 287 s. [Goryachev A.S., Savin I.A. Basics of mechanical ventilation. M.: Axiom Graphics Union LLC, 2019; 287 p. (in Russ.)].
  15. Kulen R., Gutmann J., Rossent R. Novye metody vspomogatel'noj ventiljatsii legkih. Per. s nemets. M.: Meditsina, 2004; 160 s. [Coulin R., Guttmann J., Rossent R. New methods of assisted ventilation. Trans from German. M.: Meditsina, 2004; 160 p. (in Russ.)].
  16. Kassil' V.L., Eremenko A.A., Sapicheva Ju.Ju. i dr. Printsipy mehanicheskoj ventiljatsii legkih v intensivnoj terapii. M: MEDpress-inform, 2017; 488 s. [Kassil V.L., Eremenko A.A., Sapicheva Yu.Yu. et al. The principles of mechanical ventilation in intensive care. M.: MEDpress-inform, 2017; 488 pp. (in Russ.)].
  17. Hienas V. Rannjaja neinvazivnaja respiratornaja podderzhka v intensivnoj terapii respiratornogo distressa u novorozhdennyh. Avtoref. diss. … kand. med. nauk. SPb, 2018; 19 s. [Hienas V. Early non – invasive respiratory support in intensive care of respiratory distress in nevborns. An abstract of the diss. … cand. med. sci. SPb, 2018; 19 p. (in Russ)].
  18. Intensivnaja terapija. Novoe kratkoe rukovodstvo. Pod red. Pola L. Marino. Per. s angl. M.: BINOM, 2019; 754 s. [Intensive therapy. New quick start quide. Ed. Paula L. Marino. Trans. From English. M.: BINOM, 2019; 754 p. (in Russ.)].
  19. Tsarenko S.V. Prakticheskij kurs IVL. M.: Meditsina, 2007; 160 s. [Tsarenko S.V. Practical IVL course. M.: Meditsina, 2007; 160 p. (in Russ.)].
  20. Metodicheskoe pis'mo «Pervichnaja i reanimatsionnaja pomosch' novorozhdennym detjam» №15–4/10/2-3204 ot 21.04.2010 g. Kollektiv avtorov veduschih NII. Utverzhdeno zam ministra zdravoohranenija i sotsial'nogo razvitija Rossijskoj Federatsii Skvortsovoj V.I. [Methodical Letter «Primary and resuscitation care assistance to newborn clidren» No 15-4/10/2-3204 of 04/21/2010. Team of authors. Approved by Deputy Minister of Health and Social Development of the Russian Federation V. Skvortsova (in Russ.)].