Laboratory indicators of coronАvirus infection COVID-19

DOI: https://doi.org/10.29296/25877305-2020-05-01
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Issue: 
5
Year: 
2020

Professor R. Abdullaev(1), MD; Professor O. Komissarova(1, 2), MD (1)Central Research Institute of Tuberculosis, Moscow (2)N.I. Pirogov Russian National Research Medical University, Moscow

This review provides literature data on the features of changes in the indicators of clinical and biochemical analysis of blood, as well as hemostatic and fibrinolysis systems in patients with new coronavirus infection COVID-19. It was shown that changes in indicators of clinical and biochemical blood analysis, as well as hemostatic and fibrinolysis systems with COVID-19, have their own characteristics and are closely interrelated with the severity of infection. In a clinical blood test, lymphopenia and thrombocytopenia are most common in this category of patients. Among blood biochemical parameters with COVID-19, an increase in CRP and ferritin levels, as well as a decrease in albumin levels, are more often detected. It should be noted that in ⅓ of severe patients with COVID-19 infection, the activity of liver enzymes, ALT and AST, increases. Among the indicators of hemostasis and fibrinolysis systems, an increase in the concentration of D-dimer in blood plasma is more often detected.
Keywords: 
infectious diseases
COVID-19
lymphopenia
thrombocytopenia
CRP
ferritin
D-dimer

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