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Anticancer diet, or principles of rational nutrition in gynecological cancer patients during rehabilitation

DOI: https://doi.org/10.29296/25877305-2020-04-01
Issue: 
4
Year: 
2020

A. Vlasina; Professor A. Solopova, MD; E. Ivanova; T. Blbulyan I.M. Sechenov First Moscow State Medical University (Sechenov University)

Objective: to demonstrate the relevance of the nutritional problem in gynecological cancer patients in the rehabilitation period; to formulate the goals and objectives of anticancer diet; and to highlight the most important principles of nutrition support for patients with the early stages of the disease. Basic provisions. The authors consider the scientific basis of rational nutrition in women with malignant neoplasms of the reproductive system in the rehabilitation period. Based on their significant clinical experience, the authors propose their view of the problem. The importance of nutrition support is much great that it is the latter that governs the prognosis of the disease and the risk of recurrence. Eating disorders substantially worsen the results of antitumor therapy and quality of life in gynecological cancer patients. Anticancer diet implies a multidisciplinary approach to providing good nutrition due to the diet that is optimally balanced in chemical composition and energy value, which contributes to the effective recovery of patients, to the improvement of their general condition, and to the increase in relapse-free survival. An individual selection of foods and their cooking methods, dietary pattern and water load are recommended, by taking into account calories and adequate provision of the body with micro- and macronutrients. It is important to remember the possible synergistic effects of biologically active substances and to correctly combine them. Dishes can vary in composition; however, food should provide the body’s energy needs, eliminate toxins, stimulate the immune system, promote physical performance, improve mood, and therefore increase quality of life in a woman. Conclusion. The development of an individual rational nutrition program and its compliance should be considered an important component of treatment and rehabilitation measures aimed at achieving the maximum quality of life in gynecological cancer patients.

Keywords: 
gynecologic oncology
anti-cancer diet
nutrition support
antitumor treatment
rehabilitation
quality of life
micronutrients
macronutrients



References: 
  1. Kaprin A.D., Starinskij V.V., Petrova G.V. (red.). Zlokachestvennye novoobrazovanija v Rossii v 2018 godu (zabolevaemost' i smertnost') / M.: MNIOIim. P.A. Gertsena – filial FGBU «NMITs radiologii» Minzdrava Rossii, 2019; 236 s. [Kaprin A.D., Starinskij V.V., Petrova G.V. (red.). Malignant neoplasms in Russia in 2018 (morbidity and mortality) / M.: P.A. Hertsen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of Russia Publ., 2019; 236 s. (in Russ.)].
  2. Runowicz C., Leach C., Henry N. et al. American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline // CA Cancer J. Clin. – 2016; 66 (1): 43–73. DOI: 10.3322/caac.21319
  3. Sibeoni J., Picard C., Orri M. et al. Patients’ quality of life during active cancer treatment: a qualitative study // BMC Cancer. – 2018; 18 (1): 951. DOI: 10.1186/s12885-018-4868-6
  4. Idrisova L.E., Solopova A.G., Achkasov E.E.i dr. Otsenka vlijanija reabilitatsii na kachestvo zhizni onkoginekologicheskih bol'nyh // Vopr. ginekol., akush. i perinatol. – 2019; 18 (6): 41–5 [Idrisova L.E., Solopova A.G., Achkasov E.E. et al. Assessment of the impact of rehabilitation on the quality of life of gynaecologicaloncology patients // Vopr. ginekol. akus. perinatol. = Gynecology, Obstetrics and Perinatology. – 2019; 18 (6): 41–5 (in Russ.)]. DOI: 10.20953/1726-1678-2019-6-41-45
  5. Koshiyama M. The Effects of the Dietary and Nutrient Intake on Gynecologic Cancers // Healthcare. – 2019; 7 (3): 88. DOI: 10.3390/healthcare7030088
  6. Sorokina A. Vlijanie kishechnoj mikroflory na metabolizm estrogenov i razvitie disgormonal'nyh ginekologicheskih zabolevanij // Vrach. – 2019; 30 (1): 9–15 [Sorokina A. The effect of the intestinal microflora on the metabolismof estrogens and the development of dyshormonal gynecological diseases // Vrach. – 2019; 30 (1): 9–15 (in Russ)]. https://doi.org/10.29296/25877305-2019-01-02
  7. Koutoukidis D., Beeken R., Lopes S. et al. Attitudes, challenges and needs about diet and physical activity in endometrial cancer survivors: a qualitative study // Eur. J. Cancer Care. – 2016; 26 (6): e12531. DOI: 10.1111/ecc.12531.
  8. Obuhova O.A., Kurmukov I.A., Kashija Sh.R. Pitatel'naja podderzhka v onkologii // Onkoginekologija. – 2014; 1: 34–45 [Obukhova O.A., Kurmukov I.A., Kasiya Sh.R. Nutritional support in oncology // Onkoginekologiya. – 2014; 1: 34–45 (in Russ.)].
  9. Kupchak D.V., Ljubimova O.I., Ljubimova A.A. Osnovy organizatsii lechebnogo pitanija v onkologicheskih lechebnyh uchrezhdenijah // Vestnik Habarovskogo gosudarstvennogo universiteta ekonomiki i prava. – 2017; 3 (89): 106–13. [Kupchak D.V., Lyubimova O.I., Lyubimova A.A. The basics of the organization of clinical nutrition in oncological hospitals // Bulletin of the Khabarovsk State University of Economics and Law. – 2017; 3 (89): 106–13 (in Russ.)].
  10. Runowicz C., Leach C., Henry N. et al. American Cancer Society/American Society of Clinical Oncology Breast Guideline // J. Clin. Oncol. – 2016; 34: 611–35. https://doi.org/10.1200/JCO.2015.64.3809
  11. Koshiyama M. The Effects of the Dietary and Nutrient Intake on Gynecologic Cancers // Healthcare (Basel). – 2019; 7 (3): 88. DOI: 10.3390/healthcare7030088
  12. Crane T., Khulpateea B., Alberts D. et al. Dietary intake and ovarian cancer risk: a systematic review // Cancer Epidemiol. Biomarkers Prev. – 2014; 23 (2): 255–73. DOI: 10.1158/1055-9965.EPI-13-0515
  13. Seiler A., Chen M., Brown R. et al. Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk // Curr. Breast Cancer Rep. – 2018; 10 (1): 14–27. DOI: 10.1007/s12609-018-0264-0.
  14. Hernando Requejo O., Rubio Rodriguez M. Nutrition and cancer // Nutr. Hosp. – 2015; 32 (Suppl. 1): 67–72. DOI: 10.3305/nh.2015.32.sup1.9483
  15. Gnagnarella P., Dragà D., Baggi F. et al.Promoting weight loss through diet and exercise in overweight or obese breast cancer survivors (InForma): study protocol for a randomized controlled trial // Trials. – 2016; 17: 363. DOI: 10.1186/s13063-016-1487-x
  16. Smits A., Lopes A., Das N. et al. The effect of lifestyle interventions on the quality of life of gynaecological cancer survivors // Gynecologic Oncology. – 2015; 139 (3): 546–52. DOI: 10.1016/j.ygyno.2015.10.002
  17. Arends J., Bachmann P., Baracos V. et al. ESPEN guidelines on nutrition in cancer patients // Clinical Nutrition. – 2017; 36 (1): 11–48. DOI: 10.1016/j.clnu.2016.07.015
  18. Aktas A., Walsh D., Galang M. et al. Underrecognition of malnutrition in advanced cancer: the role of the dietitian and clinical practice variations // Am. J. Hosp. Palliat. Care. – 2016; 34 (6): 547–55. https://doi.org/10.1177/1049909116639969
  19. Koshimoto S., Arimoto M., Saitou K. et al. Need and demand for nutritional counselling and their association with quality of life, nutritional status and eating-related distress among patients with cancer receiving outpatient chemotherapy: a cross-sectional study // Support Care Cancer. – 2019; 27: 3385. https://doi.org/10.1007/s00520-018-4628-9
  20. Zelenskaja E.M., Koh N.V., Slepuhina A.A. i dr. Nutrigeneticheskij test v klinicheskoj praktike: tseli i vozmozhnosti // Klinicheskaja praktika. – 2017; 3 (31): 76–82 [Zelenskaya E.M., Kokh N.V., Slepukhina A.A. et al. Nutriogenetic test in clinical practice: goals and opportunities // Klinicheskaya praktika. – 2017; 3 (31): 76–82 (in Russ.)].
  21. Gajvoronskij I.V. Nichiporuk G.I., Gajvoronskij I.N. i dr. Bioimpedansometrija kak metod otsenki komponentnogo sostava tela cheloveka (obzor literatury) // Vestnik Sankt-Peterburgskogo universiteta. – 2017; 12 (4): 365–84 [Gaivoronskiy I.V., Nichiporuk G.I. Gaivoronskiy I.N. et al. Bioimpedansometry as a method of the component bodystructure assessment (review) // Vestnik Sankt-Peterburgskogo universiteta. – 2017; 12 (4): 365–84 (in Russ)]. DOI: 10.21638/11701/spbu11.2017.406
  22. Tutel'jan V.A., Gapparov M.G., Pogozheva A.V. i dr. Metodicheskie rekomendatsii «Organizatsija lechebnogo pitanija v lechebno-profilakticheskih uchrezhdenijah» [Tutel’yan V.A., Gapparov M.G., Pogozheva A.V. et al. Metodicheskie rekomendacii «Organizaciya lechebnogo pitaniya v lechebno-profilakticheskih uchrezhdeniyah» (in Russ)]. Dostupno na / Available at: http://docs.cntd.ru/document/499029491. Data obraschenija 19.01.2020 / Accessed 19 January, 2020.
  23. Solopova A.G., Vlasina A.Ju., Idrisova L.E. i dr. Reabilitatsija onkoginekologicheskih bol'nyh: aktual'nye problemy i vozmozhnye reshenija // Vestnik vosstanovitel'noj meditsiny. – 2019; 5 (93): 87–96 [Solopova A.G., Vlasina A.Y., Idrisova L.E. et al. Rehabilitation of oncogynecological patients: current problems and possible solutions rehabilitation of oncogynecological patients: current problems and possible solutions // Vestnik vosstanovitel’noj mediciny = Journal of restorative medicine & rehabilitation. – 2019; 5 (93): 87–96 (in Russ)].
  24. Gröber U., Holzhauer P., Kisters K. et al. Micronutrients in Oncological Intervention // Nutrients. – 2016; 8 (3): 163. DOI: 10.3390/nu8030163
  25. Printsipy dieticheskogo pitanija onkologicheskih bol'nyh. Metodicheskie rekomendatsii №375 – PD/609 (Utv. Minzdravsotsrazvitija RF 20.12.06) [Principy dieticheskogo pitaniya onkologicheskih bol’nyh. Metodicheskie rekomendacii №375 – PD/609 (Utv. Minzdravsocrazvitiya RF 20.12.06) (in Russ)].
  26. Jurchenko I.A., Geras'kin V.N. Predlozhenie i obosnovanie metoda rascheta individual'nogo pitanija, pozvoljajuschego sozdat' uslovija dlja izlechivanija hronicheskih zabolevanij cheloveka v period ih remissii // Vestnik OGU. – 2011; 15 (134): 172–6 [Yurchenko I.A., Geras’kin V.N. Predlozhenie i obosnovanie metoda rascheta individual’nogo pitaniya, pozvolyayushchego sozdat’ usloviya dlya izlechivaniya khronicheskikh zabolevanii cheloveka v period ikh remissii // Vestnik OGU. – 2011; 15 (134): 172–6 (in Russ.)].
  27. Matrenitskij V.L. Zabytaja psihoonkologija: o neobhodimosti psihoterapii i psihosotsial'noj reabilitatsii v profilaktike retsidivov i metastazov onkozabolevanij // Klinicheskaja onkologija. – 2018; 8 (1): 46–52 [Matrenitsky V.L. Forgotten psycho-oncology: the need for psychotherapy and psychosocial rehabilitation in the prevention of cancer recurrence and metastases // Klinicheskaya onkologiya. – 2018; 8 (1): 46–52 (in Russ.)].
  28. Salauen H., Thariat, J., Vignot, M. et al. Obésité et cancer // Bulletin du cancer. – 2017; 104 (1): 30–41. DOI: 10.1016/j.bulcan.2016.11.012
  29. Bershtejn L.M. Epidemija «nesteroidnoj triady» (ozhirenie, diabet, metabolicheskij sindrom) i rak molochnoj zhelezy // Zlokachestvennye opuholi. – 2018; 8 (3s1): 5–8 [Bershtein L.M. Epidemiya «nesteroidnoi triady» (ozhirenie, diabet, metabolicheskii sindrom) i rak molochnoi zhelezy // Malignant tumours. – 2018; 8 (3s1): 5–8 (in Russ.)].
  30. Babaeva N.A., Ashrafjan L.A., Antonova I.B. i dr. Rol' gormonal'nyh narushenij v kantserogeneze opuholej zhenskoj reproduktivnoj sistemy // Akusherstvo i ginekologija: Novosti. Mnenija. Obuchenija. – 2017; 1 (15): 76–82 [Babaeva N.A., Ashrafyan L.A., Antonova I.B. et al. The role of hormonal disbalance in the carcinogenesis of tumors of the female reproductive system // Akusherstvo i ginekologiya: Novosti. Mneniya. Obucheniya. – 2017; 1 (15): 76–82 (in Russ.)].
  31. Terehova A.A., Neljubina E.G., Bobkova E.Ju i dr. Osnovnye printsipy organizatsii pitanija onkologicheskih bol'nyh // Paradigma. – 2019; 2: 183–90 [Terekhova A.A., Nelyubina E.G., Bobkova E.Yu et al. Osnovnye printsipy organizatsii pitaniya onkologicheskikh bol’nykh // Paradigma. – 2019; 2: 183–90 (in Russ.)].
  32. Egorova S.V., Kulakov V.G., Utjusheva E.M. i dr. Semena chia – innovatsionnyj produkt v funktsional'nom i spetsializirovannom pitanii // Pischevaja promyshlennost'. – 2018; 3: 26–7 [Egorova S.V., Kulakov V.G., Utyusheva E.M. et al. Chia seeds are an innovative product a functional and specialized nutrition // Pishchevaya promyshlennost. – 2018; 3: 26–7 (in Russ.)].
  33. Semenova E.V., Bilimenko A.S., Chebotok V.V. Ispol'zovanie morskih vodoroslej v meditsine i farmatsii // Sovremennye problemy nauki i obrazovanija. – 2019; 5: 118 [Semenova E.V., Bilimenko A.S., Chebotok V.V. The use of seaweed in medicine and pharmacy // Sovremennye problem nauki i obrazovaniya. – 2019; 5: 118 (in Russ.)].
  34. Kell G. et al. Affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial // Complement. Ther. Med. – 2017; 33: 58–64. DOI: 10.1016/j.ctim.2017.06.001
  35. Flaskerud J. Mood and food // Issues in mental health nursing. – 2015; 36 (4): 307–10. https://doi.org/10.3109/01612840.2014.962677