The role of proinflammatory cytokines in the development of renal dysfunction

DOI: https://doi.org/10.29296/25877305-2020-02-07
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Issue: 
2
Year: 
2020

I. Murkamilov(1, 2), Candidate of Medical Sciences; Professor I. Sabirov(2), MD; Professor K. Aitbaev(3), MD; Professor V. Fomin(4), MD, Corresponding Member of the Russian Academy of Sciences (1)I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan (2)First President of Russia B.N. Yeltsin Kyrgyz-Russian Slavic University, Bishkek, Kyrgyzstan (3)Research Institute of Molecular Biology and Medicine, Bishkek, Kyrgyzstan (4)I.M. Sechenov First Moscow State Medical University (Sechenov University)

The relationship of proinflammatory cytokines to glomerular filtration rate was studied in therapeutic patients at high risk for renal dysfunction.

Keywords: 
урология
почечная дисфункция
интерлейкин-6
фактор некроза опухоли-α
скорость клубочковой фильтрации



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References: 
  1. Moiseev V.S., Muhin N.A., Smirnov A.V. i dr. Serdechno-sosudistyj risk i hronicheskaja bolezn' pochek: strategii kardio-nefroprotektsii // Ros. kardiol. zhurn. – 2014; 8: 7–37 [Moiseev V.S., Mukhin N.A., Smirnov A.V. et al. Cardiovascular risk and chronic kidney disease: cardio-nephroprotection strategies // Russian Journal of Cardiology. – 2014; 8: 7–37 (in Russ.)]. https://doi.org/10.15829/1560-4071-2014-8-7-37.
  2. Bobkova I.N., Gussaova S.S., Stavrovskaja E.V. i dr. Nefrologicheskie aspekty hirurgicheskoj korrektsii massy tela pri morbidnom ozhirenii // Ter. arh. – 2018; 6 (90): 98–104 [Bobkova I.N., Gussaova S.S., Stavrovskaya E.V. et al. Nephrological aspects of surgical weight correction in morbid obesity // Therapeutic archive. – 2018; 6 (90): 98–104 (in Russ.)]. DOI: 10.26442/terarkh201890698-104.
  3. Evangelista L., Cho W., Kim Y. Obesity and chronic kidney disease: A population-based study among South Koreans // PloS One. – 2018; 13 (2): e0193559. DOI: 10.1371/journal.pone.0193559.
  4. Sharipova G.H., Chazova I.E. Narushenija funktsii pochek u bol'nyh pri metabolicheskom sindrome v sochetanii s arterial'noj gipertoniej // Ros. kardiol. zhurn. – 2009; 3: 89–95 [Sharipova G.K., Chazova I.E. Renal dysfunction in patients with metabolic syndrome and arterial hypertension // Russian Journal of Cardiology. – 2009; 3: 89–95 (in Russ.)]. https://doi.org/10.15829/1560-4071-2009-3-89-95.
  5. Shestakova M.V. Saharnyj diabet i hronicheskaja bolezn' pochek: sovremennaja diagnostika i lechenie // Vestn. RAMN. – 2012; 67 (1): 45–9 [ShestakovaM.V. Diabetes mellitus and chronic kideny disease: modern diagnostics and treatment // Vestnik Rossiiskoi akademii medetsinskikh nauk = Annals of the Russian academy of medical sciences. – 2012; 67 (1): 45–9 (in Russ.)].
  6. Losito A., Nunzi E., Pittavini L. et al. Cardiovascular morbidity and long term mortality associated with in hospital small increases of serum creatinine // J. Nephrol. – 2018; 31 (1): 71–7. https://doi.org/10.1007/s40620-017-0413-y.
  7. Eriksson J., Neovius M., Jacobson S. et al. Healthcare costs in chronic kidney disease and renal replacement therapy: a population-based cohort study in Sweden // BMJ Open. – 2016; 6 (10): e012062. https://dx.doi.org/10.1136/bmjopen-2016-012062.
  8. Luyckx V. Tonelli M., Stanifer J. The global burden of kidney disease and the sustainable development goals // Bull. WHO. – 2018; 96: 414–22D. http://dx.doi.org/10.2471/BLT.17.206441.
  9. Zahed N., Chehrazi S. The evaluation of the relationship between serum levels of Interleukin-6 and Interleukin-10 and metabolic acidosis in hemodialysis patients // Saudi J. Kidney Dis. Transpl. – 2017; 28 (1): 23–9. DOI: 10.4103/1319-2442.198106.
  10. Desjardins M., Sidibé A., Fortier C. et al. Association of interleukin-6 with aortic stiffness in end-stage renal disease // J. Am. Soc. Hypertens. – 2018; 12 (1): 5–13. https://doi.org/10.1016/j.jash.2017.09.013.
  11. Ajtbaev K.A., Murkamilov I.T., Fomin V.V. i dr. Vospalenie pri hronicheskoj bolezni pochek: istochniki, posledstvija i protivovospalitel'naja terapija // Klinicheskaja meditsina. – 2018; 96 (4): 314–20 [Aitbaev K.A., Murkamilov I.T., Fomin V.V. et al. Inflammation in chronic kidney disease: sources, consequences and anti-inflammatory therapy // Clinical medicine. – 2018; 96 (4): 314–20 (in Russ.)]. DOI: 10.18821/0023-2149-2018-96-4-314-320.
  12. Dragunov D.O., Sokolova A.V., Arutjunov G.P. i dr. Vzaimosvjaz' urovnja IL-18, IL-6 i urovnja potreblenija natrija u patsientov s gipertonicheskoj bolezn'ju i saharnym diabetom // Kardiologija. – 2017; 57 (1S): 355–9 [Dragunov D.O., Sokolova A.V., Arutyunov G.P. et al. Correlations of IL-18 and IL-6 with sodium consumption in patients with arterial hypertension and diabetes mellitus // Kardiologiia. – 2017; 57 (1S): 355–9 (in Russ.)]. https://doi.org/10.18087/cardio.2389.
  13. Kudlaj D.A. Immunometabolicheskie aspekty patogeneza politravmy. Avtoref. … diss. d-ra med. nauk. Novosibirsk: Novosibirskij gosudarstvennyj meditsinskij universitet Federal'nogo agentstva po zdravoohraneniju i sotsial'nomu razvitiju RF, 2007 [Kudlay D.A. Immunometabolicheskie aspekty patogeneza politravmy. Avtoref. … diss. d-ra med. nauk. Novosibirsk: Novosibirskii gosudarstvennyi meditsinskii universitet Federal’nogo agentstva po zdravookhraneniyu i sotsial’nomu razvitiyu RF, 2007 (in Russ.)].
  14. Gordeeva O.M., Telepnev M.V., Nikitina I.Ju. Primenenie immunologicheskih metodov v kompleksnoj diagnostike tuberkuleza u bol'nyh hronicheskoj bolezn'ju pochek v terminal'noj stadii // Vestnik TsNIIT. – 2019; S1: 55–6 [Gordeeva O.M., Telepnev M.V., Nikitina I.Yu. Primenenie immunologicheskikh metodov v kompleksnoi diagnostike tuberkuleza u bol’nykh khronicheskoi bolezn’yu pochek v terminal’noi stadii // Vestnik TsNIIT. – 2019; S1: 55–6 (in Russ.)]. DOI: 10.7868/S2587667819050273
  15. Gordeeva O.M., Telepnev M.V., Panteleev A.V. i dr. Effektivnost' immunologicheskih metodov v kompleksnoj diagnostike tuberkuleza u bol'nyh hronicheskoj bolezn'ju pochek v terminal'noj stadii // Vestnik TsNIIT. – 2018; 4: 51–7 [Gordeeva O.M., Telepnev M.V., Panteleev A.V. et al. Effectiveness of immunological methods in the complex diagnostics of tb in patients with the terminal stage of chronic renal failure // Vestnik TsNIIT. – 2019; 1: 55–6 (in Russ.)]. DOI: 10.7868/S2587667818040076
  16. Smirnov A.V., Shilov E.M., Dobronravov V.A. i dr. Natsional'nye rekomendatsii. Hronicheskaja bolezn' pochek: osnovnye printsipy skrininga, diagnostiki, profilaktiki i podhody k lecheniju // Nefrologija. – 2012; 16 (1): 89–115 [Smirnov A.V., Shilov E.M., Dobronravov V.A. et al. National guidelines. chronic kidney disease: basic principles of screening, diagnosis, prevention and treatment approaches // Nephrology (Saint-Petersburg). – 2012; 16 (1): 89–115 (in Russ.)]. https://doi.org/10.24884/1561-6274-2012-16-1-89-115.
  17. Hoek F., Kemperman F., Krediet R. A comparison between cystatin C, plasma creatinine and the Cockcroft and Gault formula for the estimation of glomerular fi ltration rate // Nephrol. Dial. Transplant. – 2003; 18 (10): 2024–31. DOI: 10.1093/ndt/gfg349.
  18. Hasan M., Sutradhar I., Gupta R. et al. Prevalence of chronic kidney disease in South Asia: a systematic review // BMC Nephrol. – 2018; 19 (1): 291. DOI: 10.1186/s12882-018-1072-5.
  19. Kato S., Chmielewski M., Honda H. et al. Aspects of immune dysfunction in end-stage renal disease // Clin. J. Am. Soc. Nephrol. – 2008; 3 (5): 1526–33. https://doi.org/10.2215/CJN.00950208.
  20. Kartamysheva N.N., Chumakova O.V., Kucherenko A.G. Faktory progressirovanija hronicheskogo pielonefrita i hronicheskogo interstitsial'nogo nefrita // Pediatrija. – 2004; 5: 50–3 [Karamysheva N.N., Chumakova O.V., Kucherenko A.G. Factors of progression of chronic pyelonephritis and chronic interstitial nephritis // Pediatrics. – 2004; 5: 50–3 (in Russ.)].
  21. Kudrjashova I.P., Ospel'nikova T.P., Ershov F.I. Dinamika pokazatelej tsitokinovogo profilja pri hronicheskom pielonefrite // Klinicheskaja nefrologija. – 2012; 4: 39–41 [Kudryashova I.P., Ospelnikova T.P., Ershov F.I. Dynamics of cytokine profile in chronic pyelonephritis // Clinical nephrology. – 2012; 3: 39–41 (in Russ.)].
  22. Malyshev M.E., Bel'skih O.A., Sorokina A.A. i dr. Informativnost' pokazatelej tsitokinovogo profilja syvorotki krovi i sljunnoj zhidkosti u bol'nyh hronicheskimi boleznjami pochek // Kurskij nauchno-prakticheskij vestnik «Chelovek i ego zdorov'e». – 2016; 1: 44–9 [Malyshev M.E., Bel’skikh O.A., Sorokina A.A. et al. Information value of indicators of serum cytokine profile and saliva in patients with chronic kidney diseases // Kursk Scientific and Practical Bulletin «Man and His Health». – 2016; 1: 44–9 (in Russ.)].
  23. Majanskij A.N. Tsitokiny i mediatornye funktsii uroepitelija v vospalitel'nyh reaktsijah mochevyvodjaschej sistemy // Tsitokiny i vospalenie. – 2003; 2 (4): 1–9 [Mayansky A.N. Cytokines and mediator functions of uroepithelial cells in inflammatory reactions of urinary tract // Cytokines and inflammation. – 2003; 2 (4): 1–9 (in Russ.)].
  24. Hénaut L., Massy Z. New insights into the key role of interleukin 6 in vascular calcification of chronic kidney disease // Nephrol. Dial. Transpl. – 2018; 33 (4): 543–8. https://doi.org/10.1093/ndt/gfx379.
  25. Bongartz G., Cramer M., Doevendans P. et al. The severe cardiorenal syndrome: Guyton revisited // Eur. Heart J. – 2005; 26 (1): 11–7. https://doi.org/10.1093/eurheartj/ehi020.
  26. Kamei N., Yamashita M., Nishizaki Y. et al. Association between circulating tumor necrosis factor-related biomarkers and estimated glomerular filtration rate in type 2 diabetes // Sci. Rep. – 2018; 8 (1): 15302. DOI: 10.1038/s41598-018-33590-w.
  27. Sonkar G., Singh R. Evaluation of serum tumor necrosis factor α and its correlation with histology in chronic kidney disease, stable renal transplant and rejection cases // Saudi J. Kidney Dis. Transpl. – 2009; 20 (6): 1000–4. URL: http://www.sjkdt.org/text.asp?2009/20/6/1000/57253
  28. Bae E., Cha R., Kim Y. et al. Circulating TNF receptors predict cardiovascular disease in patients with chronic kidney disease // Medicine. – 2017; 96 (19): e6666. DOI: 10.1097/MD.0000000000006666.
  29. An J., Yoo K., Hwang J. et al. Circulating tumour necrosis factor receptors 1 and 2 predict contrast-induced nephropathy and progressive renal dysfunction: a prospective cohort study // Nephrology (Carlton). – 2015; 20 (8): 552–9. DOI: 10.1111/nep.12448.
  30. Konenkov V.I., Klimontov V.V., Mjakina N.E. i dr. Povyshennaja kontsentratsija vospalitel'nyh tsitokinov v syvorotke krovi u bol'nyh saharnym diabetom 2-go tipa s hronicheskoj bolezn'ju pochek // Ter. arh. – 2015; 87 (6): 45–9 [Konenkov V.I., Klimontov V.V., Myakina N.E. et al. Increased serum concentrations of inflammatory cytokines in type 2 diabetic patients with chronic kidney disease // Therapeutic archive. – 2015; 87 (6): 45–9 (in Russ.)]. DOI: 10.17116/terarkh201587645-49.
  31. Crosswhite P., Sun Z. Ribonucleic Acid Interference Knockdown of Interleukin 6 Attenuates Cold-Induced Hypertension // Hypertension. – 2010; 55 (6): 1484–91. DOI: 10.1161/HYPERTENSIONAHA.109.146902.
  32. Marusanov V.E., Koren'kov D.G., Mishina T.P. i dr. Provospalitel'nye tsitokiny v opredelenii tjazhesti obostrenija hronicheskogo pielonefrita v otdelenijah skoroj meditsinskoj pomoschi statsionara // Skoraja meditsinskaja pomosch'. – 2015; 16 (4): 72–6 [Marusanov V.E., Koren’Kov D.G., Michina T.P. et al. Proinflammatory cytokines in operedelenii severity of the exacerbation of chronic pyelonephritis // Emergency medical care. – 2015; 16 (4): 72–6 (in Russ)]. https://doi.org/10.24884/2072-6716-2015-16-4-72-76.
  33. Ballardie F., Gordon M., Sharpe P. et al. Intrarenal cytokine mRNA expression and location in normal and IgA nephropathy tissue: TGF-alpha, TGF-beta, IGF-1, IL-4 and IL-6 // Nephrol. Dial. Transplant. – 1994; 9 (11): 1545–52.
  34. Murkamilov I.T., Ajtbaev K.A., Fomin V.V. i dr. Tsitokiny i arterial'naja zhestkost' na rannej stadii hronicheskoj bolezni pochek: vzaimosvjaz' i prognosticheskaja rol' // Klinicheskaja nefrologija. – 2018; 4: 25–32 [Murkamilov I.T., Aitbaev K.A., Fomin V.V. et al. Cytokines and arterial stiffness at the early stage of chronic kidney disease: the relationship and prognostic role // Clinical Nephrology. – 2018; 4: 25–32 (in Russ.)]. DOI: 10.18565/nephrology.2018.4.25-32.
  35. Murkamilov I.T., Fomin V.V., Ajtbaev K.A. i dr. Tsitokinovaja model' razvitija serdechno-sosudistyh oslozhnenij pri hronicheskoj bolezni pochek // Klinicheskaja nefrologija. – 2017; 2: 71–5 [Murkamilov I.T., Aitbaev K.A., Fomin V.V. et al. Cytokine model of the development of cardiovascular complications in chronic kidney disease // Clinical Nephrology. – 2017; 2: 71–5 (in Russ.)].