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DETECTION RATES OF ANTI-CYCLIC CITRULLINATED PEPTIDE (anti-CCP and anti-MCV) ANTIBODIES IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS AND CLINICAL CHARACTERISTICS OF SEROPOSITIVE PATIENTS

DOI: https://doi.org/10.29296/25877305-2018-05-16
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Issue: 
5
Year: 
2018

T. Shilova, Candidate of Medical Sciences; A. Pishchalnikov, MD; D. Volosnikov, MD; E. Serebryakova, Candidate of Medical Sciences South Ural State Medical University, Chelyabinsk

The paper provides data on the detection rates of antibodies against anti-cyclic citrullinated peptide (anti-CCP) and modified citrullinated vimentin (anti-MCV) in children with juvenile idiopathic arthritis and gives the clinical characteristics of seropositive patients. By and large, anti-CCP antibodies were found in 25.4% of cases. At the time of examination more than 70% of patients seropositive for anti-CCP and anti-MCV developed symmetric polyarthritis, regardless of the type of disease onset.

Keywords: 
juvenile idiopathic arthritis
anti-cyclic citrullinated peptide (anti-CCP) antibodies
modified citrullinated vimentin (anti-MCV) antibodies



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